Search Results - "Simons, ER"

Changes in monocyte functions of astronauts by Kaur, Indreshpal, Simons, Elizabeth R., Castro, Victoria A., Ott, C. Mark, Pierson, Duane L.

“…As part of the systematic evaluation of the innate immune system for long duration missions, this study focused on the antimicrobial functions of monocytes in…”
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Changes in neutrophil functions in astronauts by Kaur, Indreshpal, Simons, Elizabeth R, Castro, Victoria A, Mark Ott, C, Pierson, Duane L

“…Exploration class human spaceflight missions will require astronauts with robust immune systems. Innate immunity will be an essential element for the…”
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IL-33 Is Produced And Responded To At Elevated Levels In Peanut Allergic Humans by HayGlass, K.T, Xie, J, Chooniedass, R, Becker, A.B, Simons, E.R

“…Objectives: Test the hypothesis that peripheral blood mononuclear cells from peanut allergic humans exhibit elevated production of, and responsiveness to,…”
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Epinephrine Autoinjectors For The First-aid Treatment Of Anaphylaxis: Epinephrine Dose Ejected After 11-13 Years In Controlled Storage Conditions by Simons, K.J, Rachid, O.M, Rawas-Qalaji, M.M, Simons, E.R

“…Injection of epinephrine (E) from autoinjectors (E-autos) is the recommended first-aid treatment of anaphylaxis in community settings. Modifications to delay E…”
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Cryptococcus neoformans Resides in an Acidic Phagolysosome of Human Macrophages by LEVITZ, S. M, NONG, S.-H, SEETOO, K. F, HARRISON, T. S, SPEIZER, R. A, SIMONS, E. R

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Human Neutrophil-Mediated Nonoxidative Antifungal Activity against Cryptococcus neoformans by MAMBULA, Salamatu S, SIMONS, Elizabeth R, HASTEY, Ryan, SELSTED, Michael E, LEVITZ, Stuart M

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Distinct Roles of IL-10 in Regulation of Peanut Allergy in Humans by HayGlass, K.T, Lotoski, L.C, Xie, J, Chooniedass, R, Liem, J, Becker, A.B, Simons, E.R

“…IL-10 and the IL-10R play no detectable role in regulating peanut specific food allergy associated cytokine responses in healthy individuals, but may be…”
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Clinical pharmacology of levocetirizine, the active enantiomer of cetirizine, in children age 6-11 years by Simons, E.R., Goritz, S.S., Simons, K.J.

“…The clinical pharmacology of levocetirizine, used for allergic rhinitis and urticaria treatment in Europe, has not been studied prospectively in school-age…”
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Stability of epinephrine over five months at four different non-optimal storage conditions by Rawas-Qalaji, M.M., Simons, E.R., Simons, K.J.

“…Storage of PFES at high temperature plus low humidity appeared to compromise stability more than high temperature plus high humidity, or dark or light did…”
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Non-age related differences in thrombin responses by platelets from male patients with advanced Alzheimer's disease by Davies, T A, Fine, R E, Johnson, R J, Levesque, C A, Rathbun, W H, Seetoo, K F, Smith, S J, Strohmeier, G, Volicer, L, Delva, L

“…Alzheimer's Disease(AD), characterized by a deposition of beta-amyloid peptide (beta/A4) in the brain and in the cerebral microvasculature of affected…”
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Simultaneous measurements of cytoplasmic Ca2+ responses and intracellular pH in neutrophils of localized aggressive periodontitis (LAP) patients by Herrmann, Jens Martin, Kantarci, Alpdogan, Long, Heidi, Bernardo, John, Hasturk, Hatice, Wray, Lewis V., Simons, Elizabeth R., Van Dyke, Thomas E.

“…In view of the reports that polymorphonuclear leukocytes (PMN) of patients with localized aggressive periodontitis (LAP) exhibit hyper‐responsiveness to…”
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Human Platelets Damage Aspergillus fumigatus Hyphae and May Supplement Killing by Neutrophils by CHRISTIN, L, WYSONG, D. R, MESHULAM, T, HASTEY, R, SIMONS, E. R, DIAMOND, R. D

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Differential Responses of Human Mononuclear Phagocytes to Mycobacterial Lipoarabinomannans: Role of CD14 and the Mannose Receptor by BERNARDO, J, BILLINGSLEA, A. M, BLUMENTHAL, R. L, SEETOO, K. F, SIMONS, E. R, FENTON, M. J

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Hydroxyzine from various topical phospholipid liposomal formulations: Evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model by Elzainy, A.A.W., Gu, X., Simons, E.R., Simons, K.J.

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Cetirizine from topical rigid liposomal formulations: Evaluation of peripheral antihistaminic activity and systemic absorption in a rabbit model by Simons, K.J., Elzainy, A.A.W., Gu, X., Simons, E.R.

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Immune complex stimulation of human neutrophils involves a novel Ca2+/H+ exchanger that participates in the regulation of cytoplasmic pH: flow cytometric analysis of Ca2+/pH responses by subpopulations by Bernardo, John, Hartlaub, Hilary, Yu, Xin, Long, Heidi, Simons, Elizabeth R.

“…The activation of human phagocytic leukocytes by immune complexes (IC) or opsonized microbes via their Fc and complement receptors has been well‐described (for…”
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Opsonized Zymosan-Stimulated Granulocytes—Activation and Activity of the Superoxide-Generating System and Membrane Potential Changes by Cohen, Harvey J., Newburger, Peter E., Chovaniec, Margaret E., Whitin, John C., Simons, Elizabeth R.

“…Phagocytic cells generate superoxide in response to stimulation by opsonized particles. A continuous assay for opsonized zymosan-stimulated granulocyte…”
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Subcellular Localization of the b-Cytochrome Component of the Human Neutrophil Microbicidal Oxidase: Translocation during Activation by Borregaard, Niels, Heiple, Jeanne M., Simons, Elizabeth R., Clark, Robert A.

“…We describe a new method for subcellular fractionation of human neutrophils. Neutrophils were disrupted by nitrogen cavitation and the nuclei removed by…”
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Phospholipase D mediates Fc gamma receptor activation of neutrophils and provides specificity between high-valency immune complexes and fMLP signaling pathways by Gewirtz, Andrew T., Simons, Elizabeth R.

“…Neutrophils phagocytize high‐valency immune complexes (HIC) by an Fcγ receptor‐mediated mechanism, activating an oxidative burst and initiating degranulation…”
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Neutrophil degranulation and phospholipase D activation are enhanced if the Na+/H+ antiport is blocked by Gewirtz, Andrew T., Seetoo, Kurt F., Simons, Elizabeth R.

“…Neutrophils phagocytize high‐valency immune complexes (HIC) by an Fc receptor‐mediated mechanism. Engaging Fc receptors in this manner induces PMN to generate…”
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