Search Results - "Simons, B"

A population genetic interpretation of GWAS findings for human quantitative traits by Simons, Yuval B, Bullaughey, Kevin, Hudson, Richard R, Sella, Guy

“…Human genome-wide association studies (GWASs) are revealing the genetic architecture of anthropomorphic and biomedical traits, i.e., the frequencies and effect…”
Get full text

Fermionic superradiance in a transversely pumped optical cavity by Keeling, J, Bhaseen, M J, Simons, B D

“…Following the experimental realization of Dicke superradiance in Bose gases coupled to cavity light fields, we investigate the behavior of ultracold fermions…”
Get full text

The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives by Simons, Yuval B, Sella, Guy

“…Over the past decade, there has been both great interest and confusion about whether recent demographic events — notably the Out-of-Africa-bottleneck and…”
Get full text

The deleterious mutation load is insensitive to recent population history by Simons, Yuval B, Turchin, Michael C, Pritchard, Jonathan K, Sella, Guy

“…Jonathan Pritchard, Guy Sella and colleagues report an analysis using population genetic models to show that recent human demography is likely to have had…”
Get full text

Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis by Lohoff, T., Ghazanfar, S., Missarova, A., Koulena, N., Pierson, N., Griffiths, J. A., Bardot, E. S., Eng, C.-H. L., Tyser, R. C. V., Argelaguet, R., Guibentif, C., Srinivas, S., Briscoe, J., Simons, B. D., Hadjantonakis, A.-K., Göttgens, B., Reik, W., Nichols, J., Cai, L., Marioni, J. C.

“…Molecular profiling of single cells has advanced our knowledge of the molecular basis of development. However, current approaches mostly rely on dissociating…”
Get full text

Identification of a regeneration-organizing cell in the Xenopus tail by Aztekin, C, Hiscock, T W, Marioni, J C, Gurdon, J B, Simons, B D, Jullien, J

“…Unlike mammals, tadpoles have a high regenerative potential. To characterize this regenerative response, we performed single-cell RNA sequencing after tail…”
Get full text

Inhomogeneous phase formation on the border of itinerant ferromagnetism by Conduit, G J, Green, A G, Simons, B D

“…A variety of analytical techniques suggest that quantum fluctuations lead to a fundamental instability of the Fermi liquid that drives ferromagnetic…”
Get full text

Holographic superfluids and the dynamics of symmetry breaking by Bhaseen, M J, Gauntlett, J P, Simons, B D, Sonner, J, Wiseman, T

“…We explore the far-from-equilibrium response of a holographic superfluid using the AdS/CFT correspondence. We establish the dynamical phase diagram…”
Get full text

Toward a brain-based componential semantic representation by Binder, Jeffrey R., Conant, Lisa L., Humphries, Colin J., Fernandino, Leonardo, Simons, Stephen B., Aguilar, Mario, Desai, Rutvik H.

“…Componential theories of lexical semantics assume that concepts can be represented by sets of features or attributes that are in some sense primitive or basic…”
Get full text

Collective dynamics of Bose-Einstein condensates in optical cavities by Keeling, J, Bhaseen, M J, Simons, B D

“…Experiments on Bose-Einstein condensates in optical cavities have observed a coherent state of the matter-light system-superradiance. The nature of these…”
Get full text

The role of the interlayer state in the electronic structure of superconducting graphite intercalated compounds by Csányi, Gábor, Littlewood, P. B, Nevidomskyy, Andriy H, Pickard, Chris J, Simons, B. D

“…Although not an intrinsic superconductor, graphite exhibits superconductivity when intercalated with certain dopants. Perhaps the most studied of these…”
Get full text

The petrogenesis of the Early Permian Variscan granites of the Cornubian Batholith: Lower plate post-collisional peraluminous magmatism in the Rhenohercynian Zone of SW England by Simons, B., Shail, Robin K., Andersen, Jens C.Ø.

“…The Early Permian Cornubian Batholith was generated during an extensional regime following Variscan convergence within the Rhenohercynian Zone of SW England…”
Get full text

Finite-temperature phase diagram of a polarized Fermi condensate by Parish, M. M, Marchetti, F. M, Lamacraft, A, Simons, B. D

“…The two-component Fermi gas is the simplest fermion system exhibiting superfluidity, and as such is relevant to topics ranging from superconductivity to…”
Get full text

Correlation of B7-H3 with androgen receptor, immune pathways and poor outcome in prostate cancer: an expression-based analysis by Benzon, B, Zhao, S G, Haffner, M C, Takhar, M, Erho, N, Yousefi, K, Hurley, P, Bishop, J L, Tosoian, J, Ghabili, K, Alshalalfa, M, Glavaris, S, Simons, B W, Tran, P, Davicioni, E, Karnes, R J, Boudadi, K, Antonarakis, E S, Schaeffer, E M, Drake, C G, Feng, F, Ross, A E

“…Background: B7-H3 (CD276) , part of the B7 superfamily of immune checkpoint molecules, has been shown to have an immunomodulatory role. Its regulation,…”
Get full text

A novel tyrosine kinase switch is a mechanism of imatinib resistance in gastrointestinal stromal tumors by MAHADEVAN, D, COOKE, L, NAGLE, R, BEARSS, D, RILEY, C, SWART, R, SIMONS, B, DELLA CROCE, K, WISNER, L, IORIO, M, SHAKALYA, K, GAREWAL, H

“…KIT or alpha-platelet-derived growth factor receptor (alpha-PDGFR) activating mutations are the pathogenic mechanisms that characterize gastrointestinal…”
Get full text

Thermal State, Potential of Natural and Fan-Induced Ventilation in Enhancing Comfort of Nine Office Buildings in Southern Ghana by Koranteng, C, Simons, B, Abrokwa, K. Gyimah

“…Abstract This paper presents the outcome of a long-term study of the thermal conditions in nine office buildings in Accra and Kumasi, Ghana. As part of the…”
Get full text

The population genetics of human disease: The case of recessive, lethal mutations by Amorim, Carlos Eduardo G, Gao, Ziyue, Baker, Zachary, Diesel, José Francisco, Simons, Yuval B, Haque, Imran S, Pickrell, Joseph, Przeworski, Molly

“…Do the frequencies of disease mutations in human populations reflect a simple balance between mutation and purifying selection? What other factors shape the…”
Get full text

Androgen-induced programs for prostate epithelial growth and invasion arise in embryogenesis and are reactivated in cancer by Schaeffer, E M, Marchionni, L, Huang, Z, Simons, B, Blackman, A, Yu, W, Parmigiani, G, Berman, D M

“…Cancer cells differentiate along specific lineages that largely determine their clinical and biologic behavior. Distinct cancer phenotypes from different cells…”
Get full text

A randomized study on the effect of a wearable device using 0.75 Hz transcranial electrical stimulation on sleep onset insomnia by Simons, Stephen B., Provo, Maria, Yanoschak, Alexandra, Schmidt, Calvin, Gerrard, Isabel, Weisend, Michael, Anderson, Craig, Shimizu, Renee, Connolly, Patrick M.

“…Introduction The normal transition to sleep is characterized by a reduction in higher frequency activity and an increase in lower frequency activity in frontal…”
Get full text

Caffeine-induced synaptic potentiation in hippocampal CA2 neurons by Simons, Stephen B, Caruana, Douglas A, Zhao, Meilan, Dudek, Serena M

“…A1 adenosine receptor is antagonized by caffeine and is highly expressed in the CA2 layer of rodent hippocampus. This study now shows that caffeine can induce…”
Get full text