Search Results - "Simonova, Olga"
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Issues concerning legal support of international shipping
Published in SHS web of conferences (2022)“…The article focuses on international shipping governed by regulatory sources of a dual nature. This circumstance is due to the fact that international shipping…”
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Cyclodextrin's Effect on Permeability and Partition of Nortriptyline Hydrochloride
Published in Pharmaceuticals (Basel, Switzerland) (01-07-2023)“…Cyclodextrin-based delivery systems have been intensively used to improve the bioavailability of drugs through the modification of their pharmaceutically…”
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Correction: Volkova et al. Cyclodextrin's Effect on Permeability and Partition of Nortriptyline Hydrochloride. Pharmaceuticals 2023, 16 , 1022
Published in Pharmaceuticals (Basel, Switzerland) (29-12-2023)“…In the original publication [...]…”
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Modulation of Distribution and Diffusion through the Lipophilic Membrane with Cyclodextrins Exemplified by a Model Pyridinecarboxamide Derivative
Published in Pharmaceutics (18-05-2023)“…The main aims of the study were to disclose the influence of the structure on the solubility, distribution and permeability of the parent substances,…”
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Mechanistic Insight in Permeability through Different Membranes in the Presence of Pharmaceutical Excipients: A Case of Model Hydrophobic Carbamazepine
Published in Pharmaceutics (28-01-2024)“…The present study reports the effects of two pharmaceutical excipients of differing natures-non-ionic surfactant pluronic F127 (F127) and anionic…”
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Controlling the Solubility, Release Rate and Permeation of Riluzole with Cyclodextrins
Published in Pharmaceutics (03-06-2024)“…Riluzole (RLZ), a sodium channel-blocking benzothiazole anticonvulsant BCS class II drug, is very slightly soluble in aqueous medium. To improve aqueous…”
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A new insight into the aryl hydrocarbon receptor/cytochrome 450 signaling pathway in MG63, HOS, SAOS2, and U2OS cell lines
Published in Biochimie (01-04-2023)“…Osteosarcoma is the most common malignant tumor of bone, with rapid progressive growth, early distant metastases, and frequent recurrence after surgical…”
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TBP-Related Factor 2 as a Trigger for Robertsonian Translocations and Speciation
Published in International journal of molecular sciences (23-11-2020)“…Robertsonian (centric-fusion) translocation is the form of chromosomal translocation in which two long arms of acrocentric chromosomes are fused to form one…”
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Revisiting the Solubility-Permeability Relationship with Hydrophobic Drug Umifenovir in Pluronic Solutions: Impact of pH and Co-Solvent
Published in Pharmaceutics (27-01-2023)“…This study describes the influence of pluronic F-127 (F-127) and ethanol (EtOH) on the solubility of umifenovir (UMF) in buffer solutions of pH 2.0 and pH 7.4,…”
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New Antifungal Compound: Impact of Cosolvency, Micellization and Complexation on Solubility and Permeability Processes
Published in Pharmaceutics (04-11-2021)“…Poor solubility of new antifungal of 1,2,4-triazole class (S-119)—a structural analogue of fluconazole in aqueous media was estimated. The solubility…”
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Another Move towards Bicalutamide Dissolution and Permeability Improvement with Acetylated β-Cyclodextrin Solid Dispersion
Published in Pharmaceutics (15-07-2022)“…The complex formation of antiandrogen bicalutamide (BCL) with methylated (Me-β-CD) and acetylated (Ac-β-CD) β-cyclodextrins was investigated in buffer solution…”
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Physicochemical Profile of Antiandrogen Drug Bicalutamide: Solubility, Distribution, Permeability
Published in Pharmaceutics (18-03-2022)“…The pharmacologically relevant physicochemical properties of the antiandrogen drug bicalutamide (BCL) have been determined for the first time. Solubility in…”
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Abnormal promoter DNA hypermethylation of the integrin, nidogen, and dystroglycan genes in breast cancer
Published in Scientific reports (26-01-2021)“…Cell transmembrane receptors and extracellular matrix components play a pivotal role in regulating cell activity and providing for the concerted integration of…”
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NAP Family CG5017 Chaperone Pleiotropically Regulates Human AHR Target Genes Expression in Drosophila Testis
Published in International journal of molecular sciences (29-12-2018)“…To study the regulatory mechanism of the Aryl hydrocarbon receptor (AHR), target genes of transcription are necessary for understanding the normal…”
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Formation Thermodynamics of Carbamazepine with Benzamide, Para-Hydroxybenzamide and Isonicotinamide Cocrystals: Experimental and Theoretical Study
Published in Pharmaceutics (01-09-2022)“…Formation thermodynamic parameters for three cocrystals of carbamazepine (CBZ) with structurally related coformers (benzamide (BZA), para-hydroxybenzamide…”
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Chiral Recognition R- and RS- of New Antifungal: Complexation/Solubilization/Dissolution Thermodynamics and Permeability Assay
Published in Pharmaceutics (15-04-2022)“…Novel potential antifungal of 1,2,4-triazole class have been synthesized as pure enantiomer (R-98) and racemic (RS-186). The effect of…”
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DNA methylation markers panel can improve prediction of response to neoadjuvant chemotherapy in luminal B breast cancer
Published in Scientific reports (08-06-2020)“…Despite the advantages of neoadjuvant chemotherapy (NACT), associated toxicity is a serious complication that renders monitoring of the patients’ response to…”
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Emotional Imperatives of Late Modern Society and their Possible Social Consequences
Published in Sot͡s︡iologicheskiĭ zhurnal (29-06-2021)“…The purpose of this article is to examine the main “imperatives” of contemporary emotional culture, which may provide special research optics for a deeper…”
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Combination of hypomorphic mutations of the Drosophila homologues of aryl hydrocarbon receptor and nucleosome assembly protein family genes disrupts morphogenesis, memory and detoxification
Published in PloS one (01-04-2014)“…Aryl hydrocarbon receptor is essential for biological responses to endogenous and exogenous toxins in mammals. Its Drosophila homolog spineless plays an…”
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Antioxidant status of barley seedlings under conditions of excess manganese
Published in E3S Web of Conferences (01-01-2021)“…The system of protection against the effects of heavy metals (TM) can differ not only in different species of plants, but also in different varieties…”
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