Search Results - "Simonich, Cassandra A."

HIV-1 Neutralizing Antibodies with Limited Hypermutation from an Infant by Simonich, Cassandra A., Williams, Katherine L., Verkerke, Hans P., Williams, James A., Nduati, Ruth, Lee, Kelly K., Overbaugh, Julie

“…HIV-1 broadly neutralizing antibodies (bnAbs) develop in a subset of infected adults and exhibit high levels of somatic hypermutation (SHM) due to years of…”
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Kappa chain maturation helps drive rapid development of an infant HIV-1 broadly neutralizing antibody lineage by Simonich, Cassandra A., Doepker, Laura, Ralph, Duncan, Williams, James A., Dhar, Amrit, Yaffe, Zak, Gentles, Lauren, Small, Christopher T., Oliver, Brian, Vigdorovich, Vladimir, Mangala Prasad, Vidya, Nduati, Ruth, Sather, D. Noah, Lee, Kelly K., Matsen IV, Frederick A., Overbaugh, Julie

“…HIV-infected infants develop broadly neutralizing plasma responses with more rapid kinetics than adults, suggesting the ontogeny of infant responses could…”
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Characteristics of memory B cells elicited by a highly efficacious HPV vaccine in subjects with no pre-existing immunity by Scherer, Erin M, Smith, Robin A, Simonich, Cassandra A, Niyonzima, Nixon, Carter, Joseph J, Galloway, Denise A

“…Licensed human papillomavirus (HPV) vaccines provide near complete protection against the types of HPV that most commonly cause anogenital and oropharyngeal…”
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Neutralizing Antibody Escape during HIV-1 Mother-to-Child Transmission Involves Conformational Masking of Distal Epitopes in Envelope by GOO, Leslie, MILLIGAN, Caitlin, SIMONICH, Cassandra A, NDUATI, Ruth, OVERBAUGH, Julie

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Superinfection Drives HIV Neutralizing Antibody Responses from Several B Cell Lineages that Contribute to a Polyclonal Repertoire by Williams, Katherine L., Wang, Bingjie, Arenz, Dana, Williams, James A., Dingens, Adam S., Cortez, Valerie, Simonich, Cassandra A., Rainwater, Stephanie, Lehman, Dara A., Lee, Kelly K., Overbaugh, Julie

“…Eliciting broad and potent HIV-specific neutralizing antibody responses represents the holy grail of HIV vaccine efforts. Data from singly infected individuals…”
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Epitope-Independent Purification of Native-Like Envelope Trimers from Diverse HIV-1 Isolates by Verkerke, Hans P, Williams, James A, Guttman, Miklos, Simonich, Cassandra A, Liang, Yu, Filipavicius, Modestas, Hu, Shiu-Lok, Overbaugh, Julie, Lee, Kelly K

“…Soluble forms of trimeric HIV-1 envelope glycoprotein (Env) have long been sought as immunogens and as reagents for analysis of Env structure and function…”
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Diversity and Function of Maternal HIV-1-Specific Antibodies at the Time of Vertical Transmission by Doepker, Laura E, Simonich, Cassandra A, Ralph, Duncan, Shipley, Mackenzie M, Garrett, Meghan, Gobillot, Theodore, Vigdorovich, Vladimir, Sather, D Noah, Nduati, Ruth, Matsen, 4th, Frederick A, Overbaugh, Julie M

“…Infants of HIV-positive mothers can acquire HIV infection by various routes, but even in the absence of antiviral treatment, the majority of these infants do…”
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Characteristics of Memory B Cells Elicited by a Highly Efficacious HPV Vaccine in Subjects with No Pre-existing Immunity: e1004461 by Scherer, Erin M, Smith, Robin A, Simonich, Cassandra A, Niyonzima, Nixon, Carter, Joseph J, Galloway, Denise A

“…Licensed human papillomavirus (HPV) vaccines provide near complete protection against the types of HPV that most commonly cause anogenital and oropharyngeal…”
Get full text