Search Results - "Simonian, Aleksandr L."

Special Issue-Biosensors and Neuroscience: Is Biosensors Engineering Ready to Embrace Design Principles from Neuroscience? by Hwang, Grace M, Simonian, Aleksandr L

“…In partnership with the Air Force Office of Scientific Research (AFOSR), the National Science Foundation's (NSF) Emerging Frontiers and Multidisciplinary…”
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Immobilizing Enzymes onto Electrode Arrays by Hydrogel Photolithography to Fabricate Multi-Analyte Electrochemical Biosensors by Yan, Jun, Pedrosa, Valber A., Simonian, Aleksandr L., Revzin, Alexander

“…This paper describes a biomaterial microfabrication approach for interfacing functional biomolecules (enzymes) with electrode arrays. Poly (ethylene glycol)…”
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Stabilization and anomalous hydration of collagen fibril under heating by Gevorkian, Sasun G, Allahverdyan, Armen E, Gevorgyan, David S, Simonian, Aleksandr L, Hu, Chin-Kun

“…Type I collagen is the most common protein among higher vertebrates. It forms the basis of fibrous connective tissues (tendon, chord, skin, bones) and ensures…”
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CRISPR/Cas Technology: The Unique Synthetic Biology Genome-Editing Tool Shifting the Paradigm in Viral Diagnostics, Defense, and Therapeutics by Zhou, Lang, Simonian, Aleksandr L

“…The emergence of the COVID-19 pandemic has starkly exposed our significantly limited ability to promptly identify and respond to emergent biological threats…”
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Lysozyme-mediated formation of protein–silica nano-composites for biosensing applications by Ramanathan, Madhumati, Luckarift, Heather R., Sarsenova, Ainur, Wild, James R., Ramanculov, Erlan K., Olsen, Eric V., Simonian, Aleksandr L.

“…We demonstrate a rapid method for enzyme immobilization directly on a waveguide surface by encapsulation in a silica matrix. Organophosphate hydrolase (OPH),…”
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A novel layer-by-layer assembled multi-enzyme/CNT biosensor for discriminative detection between organophosphorus and non-organophosphrus pesticides by Zhang, Yuanyuan, Arugula, Mary A, Wales, Melinda, Wild, James, Simonian, Aleksandr L

“…Organophosphate compounds are heavily used in agriculture and military activities, while non-organophosphate pesticides are mostly used in agriculture and home…”
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Strong Antimicrobial Coatings: Single-Walled Carbon Nanotubes Armored with Biopolymers by Nepal, Dhriti, Balasubramanian, Shankar, Simonian, Aleksandr L, Davis, Virginia A

“…Large scale biomimetic single-walled carbon nanotube (SWNT) coatings with significant antimicrobial activity, high Young’s Modulus, and controlled morphology…”
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Enzyme-encapsulated silica monolayers for rapid functionalization of a gold surface by Luckarift, Heather R., Balasubramanian, Shankar, Paliwal, Sheetal, Johnson, Glenn R., Simonian, Aleksandr L.

“…We report a simple and rapid method for the deposition of amorphous silica onto a gold surface. The method is based on the ability of lysozyme to mediate the…”
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Lytic phage as a specific and selective probe for detection of Staphylococcus aureus—A surface plasmon resonance spectroscopic study by Balasubramanian, Shankar, Sorokulova, Iryna B., Vodyanoy, Vitaly J., Simonian, Aleksandr L.

“…Rapid and reliable detection of harmful pathogens at low levels are vital due to the related environmental and economical impact. While antibodies (monoclonal…”
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Simultaneous Surface Plasmon Resonance/Fluorescence Spectroelectrochemical in Situ Monitoring of Dynamic Changes on Functional Interfaces: A Study of the Electrochemical Proximity Assay Model System by Zhou, Lang, Arugula, Mary A, Chin, Bryan A, Simonian, Aleksandr L

“…Understanding the chemical composition and morphology of interfaces plays a vital role in the development of sensors, drug delivery systems, coatings for…”
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Electrochemical properties of interface formed by interlaced layers of DNA- and lysozyme-coated single-walled carbon nanotubes by Pedrosa, Valber A., Gnanaprakasa, Tony, Balasubramanian, Shankar, Olsen, Eric V., Davis, Virginia A., Simonian, Aleksandr L.

“…Multifunctional coatings were produced by the layer by layer assembly of single-walled carbon nanotubes (SWNT) dispersed in DNA and lysozyme (LSZ) on an…”
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Anti-fouling PEDOT:PSS modification on glassy carbon electrodes for continuous monitoring of tricresyl phosphate by Yang, Xiaoyun, Kirsch, Jeffrey, Olsen, Eric V., Fergus, Jeffrey W., Simonian, Aleksandr L.

“…In this paper the application of poly(3,4-ethlenedioxythiophene)-poly(styrene sulphonate) (PEDOT:PSS) as an anti-fouling modification on a glassy carbon…”
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Layer-by-Layer Assembled Carbon Nanotube-Acetylcholinesterase/Biopolymer Renewable Interfaces: SPR and Electrochemical Characterization by Zhang, Yuanyuan, Arugula, Mary A, Kirsch, Jeffrey S, Yang, Xiaoyun, Olsen, Eric, Simonian, Aleksandr L

“…Developing simple, reliable, and cost-effective methods of renewing an inhibited biocatalyst (e.g., enzymatic interfaces) on biosensors is needed to advance…”
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Poly(ethylene glycol) Hydrogel-Encapsulated Fluorophore−Enzyme Conjugates for Direct Detection of Organophosphorus Neurotoxins by Russell, Ryan J, Pishko, Michael V, Simonian, Aleksandr L, Wild, James R

“…A simple approach is described for preparing poly(ethylene glycol) hydrogel materials with encapsulated seminapthofluorescein (SNAFL)−organophosphorus…”
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Phage as a molecular recognition element in biosensors immobilized by physical adsorption by Nanduri, Viswaprakash, Sorokulova, Iryna B., Samoylov, Alexandre M., Simonian, Aleksandr L., Petrenko, Valery A., Vodyanoy, Vitaly

“…Biosensors based on landscape phages immobilized by physical adsorption on the surface of a quartz crystal microbalance was used for detection of…”
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Detecting interferon-gamma release from human CD4 T-cells using surface plasmon resonance by Stybayeva, Gulnaz, Kairova, Markhabat, Ramanculov, Erlan, Simonian, Aleksandr L., Revzin, Alexander

“…Cytokine secretion by leukocytes is an important indicator of immune response to pathogens and therefore has significant implications in disease diagnostics…”
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Micropatterned Nanocomposite Hydrogels for Biosensing Applications by Pedrosa , Valber A., Yan, Jun, Simonian, Aleksandr L., Revzin, Alexander

“…This paper describes the use of Au nanoparticle (NP)‐containing hydrogel microstructures in the development of electrochemical enzyme‐based biosensors. To…”
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Renewable Nanocomposite Layer-by-Layer Assembled Catalytic Interfaces for Biosensing Applications by Mantha, Saroja, Pedrosa, Valber A, Olsen, Eric V, Davis, Virginia A, Simonian, Aleksandr L

“…A novel, easily renewable nanocomposite interface based on layer-by-layer (LbL) assembled cationic/anionic layers of carbon nanotubes customized with…”
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Highly sensitive phage-based biosensor for the detection of β-galactosidase by Nanduri, Viswaprakash, Balasubramanian, Shankar, Sista, Srinivas, Vodyanoy, Vitaly J., Simonian, Aleksandr L.

“…Development of real-time sensor based on the target-specific probe that make possible sensitive, rapid and selective detection and monitoring of the particular…”
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Affinity and enzyme-based biosensors: recent advances and emerging applications in cell analysis and point-of-care testing by Liu, Ying, Matharu, Zimple, Howland, Michael C., Revzin, Alexander, Simonian, Aleksandr L.

“…The applications of biosensors range from environmental testing and biowarfare agent detection to clinical testing and cell analysis. In recent years,…”
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