Search Results - "Simonian, A. L."

Array biosensor based on enzyme kinetics monitoring by fluorescence spectroscopy: Application for neurotoxins detection by Ramanathan, M., Simonian, A.L.

“…The aim of the present work is to develop an evanescence wave array biosensor exploiting the “kinetic” approach of enzymatic reaction and further detection of…”
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Nanoparticle-based optical biosensors for the direct detection of organophosphate chemical warfare agents and pesticides by Simonian, A.L., Good, T.A., Wang, S.-S., Wild, J.R.

“…Neurotoxic organophosphates (OP) have found widespread use in the environment for insect control. In addition, there is the increasing threat of use of OP…”
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Thermal (in)stability of type I collagen fibrils by Gevorkian, S G, Allahverdyan, A E, Gevorgyan, D S, Simonian, A L

“…We measured the Young's modulus at temperatures ranging from 20 to 100 degrees C for a collagen fibril that is taken from a rat's tendon. The hydration change…”
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FET-Based Biosensors for The Direct Detection of Organophosphate Neurotoxins by Simonian, A. L., Flounders, A. W., Wild, J. R.

“…Recent world‐wide terrorist events associated with the threat of hazardous chemical agent proliferation, and outbreaks of chemical contamination in the food…”
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The development of a new biosensor based on recombinant E. coli for the direct detection of organophosphorus neurotoxins by Rainina, E.I., Efremenco, E.N., Varfolomeyev, S.D., Simonian, A.L., Wild, J.R.

“…A new biosensor for the direct detection of organophosphorus (OP) neurtoxins has been developed utilizing cryoimmobilized, recombinant E. coli cells capable of…”
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Poly(ethylene glycol) Hydrogel-Encapsulated Fluorophore−Enzyme Conjugates for Direct Detection of Organophosphorus Neurotoxins by Russell, Ryan J, Pishko, Michael V, Simonian, Aleksandr L, Wild, James R

“…A simple approach is described for preparing poly(ethylene glycol) hydrogel materials with encapsulated seminapthofluorescein (SNAFL)−organophosphorus…”
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Enzyme-based biosensor for the direct detection of fluorine-containing organophosphates by Simonian, A.L, Grimsley, J.K, Flounders, A.W, Schoeniger, J.S, Cheng, Tu-Chen, DeFrank, J.J, Wild, J.R

“…The ability of the enzyme organophosphorus acid anhydrolase (OPAA) to selectively hydrolyze the PF bond of fluorine containing organophosphates has been used…”
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Discriminative detection of neurotoxins in multi-component samples by Simonian, A.L, Efremenko, E.N, Wild, J.R

“…In order to develop a new strategy for the detection and discrimination of neurotoxins, the competing anti-acetylcholinesterase activities of mixtures of…”
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An enzyme based biosensor for the direct determination of diisopropyl fluorophosphate by Simonian, A.L, diSioudi, B.D, Wild, J.R

“…The ability of organophosphate hydrolase (OPH, EC 3.1.8.1) from Pseudomonas diminuta to hydrolyze diisopropyl fluorophosphate (DFP) was used to develop a…”
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The influence of external environment fluctuations on the signal formation of microbiosensors by Arakelian, V.B., Wild, J.R., Simonian, A.L.

“…This part of theoretical analysis describes the fluctuations of output signal of microbiosensors when the number of accessible molecular recognition elements…”
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Lysozyme-mediated formation of protein–silica nano-composites for biosensing applications by Ramanathan, Madhumati, Luckarift, Heather R., Sarsenova, Ainur, Wild, James R., Ramanculov, Erlan K., Olsen, Eric V., Simonian, Aleksandr L.

“…We demonstrate a rapid method for enzyme immobilization directly on a waveguide surface by encapsulation in a silica matrix. Organophosphate hydrolase (OPH),…”
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A tryptophan-2-monooxygenase based amperometric biosensor for L-tryptophan determination: use of a competitive inhibitor as a tool for selectivity increase by Simonian, A.L, Rainina, E.I, Fitzpatrick, P.F, Wild, J.R

“…A new flow-injection amperometric biosensor based on immobilized tryptophan-2-monooxygenase (TMO) has been developed for reagentless L-tryptophan…”
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Copper nanoparticles and carbon nanotubes-based electrochemical sensing system for fast identification of tricresyl-phosphate in aqueous samples and air by Pedrosa, Valber A., Epur, Rigved, Benton, Jessica, Overfelt, Ruel A., Simonian, Aleksandr L.

“…An electrochemical method has been developed for the determination of tricresyl phosphate (TCP) in aqueous media and air. Although TCP is not an electroactive…”
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A New Approach For Discriminative Detection of Organophosphate Neurotoxins in the Presence of Other Cholinesterase Inhibitors by Simonian, A. L., Rainina, E. I., Wild, J. R.

“…A radically new approach for the discriminative determination of various neurotoxins has been developed. This novel biosensor combines a highly sensitive…”
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Investigation of stochastic fluctuations in the signal formation of microbiosensors by Arakelian, V.B., Wild, J.R., Simonian, A.L.

“…With a decrease in the dimensions of microbiosensors, the stochastic variation in the number of substrate complexes with the molecular recognition elements of…”
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L-Lysine-2-monooxygenase production by strains of Pseudomonas fluorescens and P. putida by KHACHATRIAN, G. E, MKRTCHIAN, N. I, KHACHATRIAN, T. V, SIMONIAN, A. L

“…Twelve strains of Pseudomonas fluorescens and P. putida were grown in a synthetic medium that contained L-lysine as the only source of carbon and nitrogen, and…”
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A biosensor for L-proline determination by use of immobilized microbial cells by Simonian, A L, Rainina, E I, Lozinsky, V I, Badalian, I E, Khachatrian, G E, Tatikian, S Sh, Makhlis, T A, Varfolomeyev, S D

“…A biosensor to quantify L-proline within 10(-5)-10(-3) mole/L concentration is described. Immobilized Pseudomonas sp. cells grown in a medium containing…”
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Thermal (in)stability of type I collagen fibrils by Gevorkian, S. G, Allahverdyan, A. E, Gevorgyan, D. S, Simonian, A. L

“…We measured Young's modulus at temperatures ranging from 20 to 100 ^{\circ}$C for a collagen fibril taken from rat's tendon. The hydration change under heating…”
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Cell biosensor for detection of phenol in aqueous solutions by Rainina, E.I, Badalian, I.E, Ignatov, O.V, Fedorov, A.Y, Simonian, A.L, Varfolomeyev, S.D

“…A microbial sensor for concentration measurement of phenol in aqueous solutions has been developed. Phenol-utilizing cells Pseudomonas putida GFS-8 immobilized…”
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Direct and discriminative detection of organophosphate neurotoxins for food and agriculture products by Kirsch, J., Davis, V. A., Simonian, A. L.

“…Organophosphate neurotoxins are well known as a class of acute toxins with significant immediate and delayed impacts on human health. There is a growing need…”
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