Search Results - "Simonen, M"
-
1
Human enterovirus infections in children at increased risk for type 1 diabetes: the Babydiet study
Published in Diabetologia (01-12-2011)“…Aims/hypothesis The aim of this study was to examine human enteroviruses (HEVs) and other intestinal viruses derived from children who participated in the…”
Get full text
Journal Article -
2
Early life determinants of frailty in old age: the Helsinki Birth Cohort Study
Published in Age and ageing (01-07-2018)“…Abstract Background there is evidence suggesting that several chronic diseases have their origins in utero and that development taking place during sensitive…”
Get full text
Journal Article -
3
Conjugated Bile Acids Associate with Altered Rates of Glucose and Lipid Oxidation after Roux-en-Y Gastric Bypass
Published in Obesity surgery (01-09-2012)“…Background Laparoscopic Roux-en-Y gastric bypass (RYGB) induces a more favorable metabolic profile than expected by weight loss alone. In this study, we…”
Get full text
Journal Article -
4
Early life stress and frailty in old age: the Helsinki birth cohort study
Published in BMC geriatrics (13-08-2018)“…Evidence suggests that early life stress (ELS) may extend its effect into adulthood and predispose an individual to adverse health outcomes. We investigated…”
Get full text
Journal Article -
5
Infant and childhood growth and frailty in old age: the Helsinki Birth Cohort Study
Published in Aging clinical and experimental research (01-05-2019)“…Background Evidence from life course studies highlights the importance of infant and childhood growth as risk factors for adulthood chronic diseases. Methods…”
Get full text
Journal Article -
6
Relationship between physical activity and physical performance in later life in different birth weight groups
Published in Journal of developmental origins of health and disease (01-02-2018)“…There is strong evidence that physical activity (PA) has an influence on physical performance in later life. Also, a small body size at birth has been…”
Get more information
Journal Article -
7
Protein secretion in Bacillus species
Published in Microbiological reviews (01-03-1993)“…Bacilli secrete numerous proteins into the environment. Many of the secretory proteins, their export signals, and their processing steps during secretion have…”
Get full text
Journal Article -
8
Upregulation of alpha globin promotes apoptotic cell death in the hematopoietic cell line FL5.12
Published in Apoptosis (London) (01-10-2005)“…The function of alpha globin in the context of oxygen transport in erythroid cells is well described. Recently the expression of alpha globin was shown to be…”
Get full text
Journal Article -
9
Hematopoietic transcription factor GATA-2 promotes upregulation of alpha globin and cell death in FL5.12 cells
Published in Apoptosis (London) (01-10-2005)“…Recently we showed that alpha globin is a novel pro-apoptotic factor in programmed cell death in the pro-B cell line, FL5.12. Alpha globin was also upregulated…”
Get full text
Journal Article -
10
Hypothyroidism after radiotherapy for laryngeal cancer
Published in Radiotherapy and oncology (01-10-2000)“…Purpose: To investigate the incidence of hypothyroidism after radiotherapy of laryngeal cancer, including the possible factors that could predict the onset of…”
Get full text
Journal Article -
11
Enteric Viruses in a Large Waterborne Outbreak of Acute Gastroenteritis in Finland
Published in Food and environmental virology (01-03-2009)“…In Nokia city about 450,000 l of treated sewage water was for 2 days allowed to run into the drinking water supplies of the city due to a personal error of one…”
Get full text
Journal Article -
12
The role of the carrier protein and disulfide formation in the folding of beta-lactamase fusion proteins in the endoplasmic reticulum of yeast
Published in The Journal of biological chemistry (13-05-1994)“…We have studied the relationship between folding and secretion competence of hsp150-beta lactamase fusion proteins in Saccharomyces cerevisiae. hsp150 is a…”
Get full text
Journal Article -
13
Systemic Deletion of the Myelin-Associated Outgrowth Inhibitor Nogo-A Improves Regenerative and Plastic Responses after Spinal Cord Injury
Published in Neuron (Cambridge, Mass.) (24-04-2003)“…To investigate the role of the myelin-associated protein Nogo-A on axon sprouting and regeneration in the adult central nervous system (CNS), we generated…”
Get full text
Journal Article -
14
Nogo-A Inhibits Neurite Outgrowth and Cell Spreading with Three Discrete Regions
Published in The Journal of neuroscience (02-07-2003)“…Nogo-A is a potent neurite growth inhibitor in vitro and plays a role both in the restriction of axonal regeneration after injury and in structural plasticity…”
Get full text
Journal Article -
15
Physicochemical properties of bitumens modified with bioflux
Published in Road materials and pavement design (01-03-2013)“…Five laboratory-produced cut-back bitumens with same target viscosity of 600 mm 2 /s at 60°C were investigated to determine the effect of chemical composition…”
Get full text
Journal Article -
16
Curing and ageing of biofluxed bitumen: a physicochemical approach
Published in Road materials and pavement design (01-03-2013)“…Bitumen solutions, comprising of four bioflux-modified bitumens and one traditional slow-curing cut-back bitumen as a reference, were stabilised with…”
Get full text
Journal Article -
17
Synthesis of OmpA Protein of Escherichia coli K12 in Bacillus subtilis
Published in Journal of general microbiology (01-03-1986)“…Recombinant DNA Laboratory, University of Helsinki, SF-00380 Helsinki, Finland National Public Health Institute, SF-00280 Helsinki, Finland ABSTRACT SUMMARY:…”
Get full text
Journal Article -
18
Nogo-A Expressed in Schwann Cells Impairs Axonal Regeneration after Peripheral Nerve Injury
Published in The Journal of cell biology (14-10-2002)“…Injured axons in mammalian peripheral nerves often regenerate successfully over long distances, in contrast to axons in the brain and spinal cord (CNS)…”
Get full text
Journal Article -
19
SH3GLB, a New Endophilin-Related Protein Family Featuring an SH3 Domain
Published in Genomics (San Diego, Calif.) (15-01-2001)“…A new cDNA encoding a protein of 362 amino acids designated SH3GLB1, for SH3 domain GRB2-like endophilin B1, was identified in a yeast two-hybrid screen…”
Get full text
Journal Article -
20
Protein secretion in Bacillus species
Published in Microbiological reviews (01-03-1993)“…Bacilli secrete numerous proteins into the environment. Many of the secretory proteins, their export signals, and their processing steps during secretion have…”
Get full text
Journal Article