Search Results - "Simon, Zoltán"
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HISTORICAL FUTURES
Published in History and theory :Studies in the philosophy of history (01-03-2021)“…ABSTRACT This article outlines the agenda of a collective research project that aims to explore modalities of historical futures that constitute our current…”
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TWO CULTURES OF THE POSTHUMAN FUTURE
Published in History and theory :Studies in the philosophy of history (01-06-2019)“…ABSTRACT The posthuman has been looming large on the human horizon lately. Yet there is no shared understanding of what a posthuman future could possibly mean,…”
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THE EXPRESSION OF HISTORICAL EXPERIENCE
Published in History and theory :Studies in the philosophy of history (01-05-2015)“…The theory and philosophy of history (just like philosophy in general) has established a dogmatic dilemma regarding the issue of language and experience:…”
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INTRODUCTION: ASSESSING NARRATIVISM
Published in History and theory :Studies in the philosophy of history (01-05-2015)“…In this introductory essay we briefly discuss three issues. First, we take stock of and pay tribute to the main achievements of narrativism, on the one hand…”
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Drug Effect Prediction by Polypharmacology-Based Interaction Profiling
Published in Journal of chemical information and modeling (23-01-2012)“…Most drugs exert their effects via multitarget interactions, as hypothesized by polypharmacology. While these multitarget interactions are responsible for the…”
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Utopia without us?
Published in Esboços (15-01-2021)“…As the prospect of self-authored human extinction increasingly appears as a plausible scenario of human futures, a growing number of efforts aim at…”
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Virtual Affinity Fingerprints for Target Fishing: A New Application of Drug Profile Matching
Published in Journal of chemical information and modeling (28-01-2013)“…We recently introduced Drug Profile Matching (DPM), a novel virtual affinity fingerprinting bioactivity prediction method. DPM is based on the docking profiles…”
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Contribution of 2D and 3D Structural Features of Drug Molecules in the Prediction of Drug Profile Matching
Published in Journal of chemical information and modeling (23-07-2012)“…Drug Profile Matching (DPM), a novel virtual affinity fingerprinting method capable of predicting the medical effect profiles of small molecules, was…”
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The limits of Anthropocene narratives
Published in European journal of social theory (01-05-2020)“…The rapidly growing transdisciplinary enthusiasm about developing new kinds of Anthropocene stories is based on the shared assumption that the Anthropocene…”
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Temperature dependence of internal friction in enzyme reactions
Published in The FASEB journal (01-08-2011)“…ABSTRACT Our aim was to elucidate the physical background of internal friction of enzyme reactions by investigating the temperature dependence of internal…”
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Domesticating the future through history
Published in Time & society (01-11-2021)“…In the most general sense, the modern idea of history is a conceptual tool deployed in order to domesticate experienced novelty and expectations of the future…”
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THE OPENING OF HISTORICAL FUTURES
Published in History and theory :Studies in the philosophy of history (01-09-2024)“…ABSTRACT With a touch of irony, the project‐closing piece of the “Historical Futures” collective research endeavor pulls together the threads of its four years…”
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The story of humanity and the challenge of posthumanity
Published in History of the human sciences (01-04-2019)“…Today’s technological-scientific prospect of posthumanity simultaneously evokes and defies historical understanding. On the one hand, it implies a historical…”
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Enzyme Kinetics above Denaturation Temperature: A Temperature-Jump/Stopped-Flow Apparatus
Published in Biophysical journal (15-12-2006)“…We constructed a “temperature-jump/stopped-flow” apparatus that allows us to study fast enzyme reactions at extremely high temperatures. This apparatus is a…”
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Temporal comparisons: Evaluating the world through historical time
Published in Time & society (01-11-2021)“…This introduction describes the main themes of the special issue on temporal comparisons. It provides the background for individual contributions by sketching…”
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THE ANTHROPOCENE AND THE PLANET
Published in History and theory :Studies in the philosophy of history (01-06-2023)“…ABSTRACT Dipesh Chakrabarty's The Climate of History in a Planetary Age is, in three respects, far more than a synthesis of over a decade of pioneering…”
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Why the Anthropocene has no history: Facing the unprecedented
Published in The anthropocene review (01-12-2017)“…This paper argues that the tendency to invoke modern historical thinking in trying to make sense of the Anthropocene amounts to an untenable,…”
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Historicism and constructionism: rival ideas of historical change
Published in History of European ideas (17-11-2019)“…A seemingly unitary appeal to history might evoke today two incompatible operations of historicization that yield contradictory results. This article attempts…”
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(The impossibility of) acting upon a story that we can believe
Published in Rethinking history (02-01-2018)“…The historical sensibility of Western modernity is best captured by the phrase 'acting upon a story that we can believe'. Whereas the most famous stories of…”
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Thermodynamic Analysis Reveals Structural Rearrangement during the Acylation Step in Human Trypsin 4 on 4-Methylumbelliferyl 4-Guanidinobenzoate Substrate Analogue
Published in The Journal of biological chemistry (05-05-2006)“…Human trypsin 4 is an unconventional serine protease that possesses an arginine at position 193 in place of the highly conserved glycine. Although this single…”
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