Search Results - "Simon, Vernadette"

Quantitative miRNA expression analysis using fluidigm microfluidics dynamic arrays by Jang, Jin Sung, Simon, Vernadette A, Feddersen, Rod M, Rakhshan, Fariborz, Schultz, Debra A, Zschunke, Michael A, Lingle, Wilma L, Kolbert, Christopher P, Jen, Jin

“…MicroRNAs (miRNAs) represent a growing class of small non-coding RNAs that are important regulators of gene expression in both plants and animals. Studies have…”
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Pediatric brain tumor cell lines exhibit miRNA-depleted, Y RNA-enriched extracellular vesicles by Magaña, Setty M., Peterson, Timothy E., Evans, Jared E., Decker, Paul A., Simon, Vernadette, Eckel-Passow, Jeanette E., Daniels, David J., Parney, Ian F.

“…Background Medulloblastoma (MB) and diffuse infiltrative pontine glioma (DIPG) are malignant pediatric tumors. Extracellular vesicles (EVs) and their bioactive…”
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Common Oncogene Mutations and Novel SND1-BRAF Transcript Fusion in Lung Adenocarcinoma from Never Smokers by Jang, Jin Sung, Lee, Adam, Li, Jun, Liyanage, Hema, Yang, Yanan, Guo, Lixia, Asmann, Yan W., Li, Peter W., Erickson-Johnson, Michele, Sakai, Yuta, Sun, ZhiFu, Jeon, Hyo-Sung, Hwang, Hayoung, Bungum, Aaron O., Edell, Eric S., Simon, Vernadette A., Kopp, Karla J., Eckloff, Bruce, Oliveira, Andre M., Wieben, Eric, Aubry, Marie Christine, Yi, Eunhee, Wigle, Dennis, Diasio, Robert B., Yang, Ping, Jen, Jin

“…Lung adenocarcinomas from never smokers account for approximately 15 to 20% of all lung cancers and these tumors often carry genetic alterations that are…”
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Multi-platform analysis of microRNA expression measurements in RNA from fresh frozen and FFPE tissues by Kolbert, Christopher P, Feddersen, Rod M, Rakhshan, Fariborz, Grill, Diane E, Simon, Gyorgy, Middha, Sumit, Jang, Jin Sung, Simon, Vernadette, Schultz, Debra A, Zschunke, Michael, Lingle, Wilma, Carr, Jennifer M, Thompson, E Aubrey, Oberg, Ann L, Eckloff, Bruce W, Wieben, Eric D, Li, Peter, Yang, Ping, Jen, Jin

“…MicroRNAs play a role in regulating diverse biological processes and have considerable utility as molecular markers for diagnosis and monitoring of human…”
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A Protocol for the Cryopreservation of Human Intestinal Mucosal Biopsies Compatible With Single-Cell Transcriptomics and Ex Vivo Studies by McRae, Alison, Ricardo-Silgado, Maria Laura, Liu, Yuanhang, Calderon, Gerardo, Gonzalez-Izundegui, Daniel, Rohakhtar, Fariborz Rakhshan, Simon, Vernadette, Li, Ying, Acosta, Andres

“…The heterogeneity of the human intestinal epithelium has hindered the understanding of the pathophysiology of distinct specialized cell types on a single-cell…”
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Characterization and Optimization of Multiomic Single-Cell Epigenomic Profiling by Sandoval, Leticia, Mohammed Ismail, Wazim, Mazzone, Amelia, Dumbrava, Mihai, Fernandez, Jenna, Munankarmy, Amik, Lasho, Terra, Binder, Moritz, Simon, Vernadette, Kim, Kwan Hyun, Chia, Nicholas, Lee, Jeong-Heon, Weroha, S John, Patnaik, Mrinal, Gaspar-Maia, Alexandre

“…The snATAC + snRNA platform allows epigenomic profiling of open chromatin and gene expression with single-cell resolution. The most critical assay step is to…”
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Protocol for isolating immune cells from human gastric muscularis propria for single-cell analysis by AlAsfoor, Shefaa, Bernard, Cheryl E., Jessen, Erik, Simon, Vernadette A., Rakhshan, Fariborz, Cipriani, Gianluca, Hsi, Linda C., Patraw, Jack A., Carothers, Kari J., Lau, Julie S., McDonough, Samantha J., Dasari, Surendra, Farrugia, Gianrico, Grover, Madhusudan

“…Understanding the diversity of gastrointestinal (GI) immune cells, especially in the muscularis propria, is crucial for understanding their role in the…”
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Noncanonical TRAIL Signaling Promotes Myeloid-Derived Suppressor Cell Abundance and Tumor Growth in Cholangiocarcinoma by Loeuillard, Emilien J., Li, Binbin, Stumpf, Hannah E., Yang, Jingchun, Willhite, Jessica R., Tomlinson, Jennifer L., Rohakhtar, Fred Rakhshan, Simon, Vernadette A., Graham, Rondell P., Smoot, Rory L., Dong, Haidong, Ilyas, Sumera I.

“…Proapoptotic tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) signaling as a cause of cancer cell death is a well-established mechanism…”
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Microarray Analysis of Diurnal and Circadian-Regulated Genes in Arabidopsis by Schaffer, Robert, Landgraf, Jeff, Accerbi, Monica, Simon, Vernadette, Larson, Matt, Wisman, Ellen

“…Plants respond to day/night cycling in a number of physiological ways. At the mRNA level, the expression of some genes changes during the 24-hr period. To…”
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Correction: Multi-Platform Analysis of MicroRNA Expression Measurements in RNA from Fresh Frozen and FFPE Tissues by Kolbert, Christopher P., Feddersen, Rod M., Rakhshan, Fariborz, Grill, Diane E., Simon, Gyorgy, Middha, Sumit, Jang, Jin Sung, Simon, Vernadette, Schultz, Debra A., Zschunke, Michael, Lingle, Wilma, Carr, Jennifer M., Thompson, E. Aubrey, Oberg, Ann L., Eckloff, Bruce W., Wieben, Eric D., Li, Peter, Yang, Ping, Jen, Jin

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516 UROCORTIN 3 EXPRESSION IN HUMAN ENTEROENDOCRINE CELLS AND CORRELATION WITH PLASMA GLP1 LEVELS IN HUMAN OBESITY by Silgado, Maria Laura Ricardo, Yun, Changho, Mcrae, Alison, Calderon, Gerardo, Izundegui, Daniel Gonzalez, Leggett, Cadman L., Simon, Vernadette, Liu, Yuanhuang, Li, Ying, Acosta, Andres

“…Enteroendocrine cells (EECs) are hormone secretory cells sparsely distributed throughout the GI tract, and implicated in obesity. Intestinal L-type EECs…”
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18 COVID-19 AND THE GUT IN HUMAN OBESITY: OVEREXPRESSION OF SARS-COV-2 RECEPTORS REVEALED BY DEEP SINGLE CELL RNA-SEQ by Mcrae, Alison, Silgado, Maria Laura Ricardo, Calderon, Gerardo, Izundegui, Daniel Gonzalez, Leggett, Cadman L., Simon, Vernadette, Liu, Yuanhuang, Li, Ying, Carlson, Paula, Badley, Andrew, Camilleri, Michael, Acosta, Andres

“…Obesity is a major risk factor for severe coronavirus disease, and clinical evidence now supports the GI tract, in addition to the respiratory system, as a…”
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Su561 OVEREXPRESSION OF REGULATOR OF G-PROTEIN SIGNALING (RGS) IN OBESITY CONTRIBUTES TO IMPAIRED GPCR-MEDIATED HORMONE SECRETION IN HUMAN ENTEROEDOCRINE CELLS: A SINGLE-CELL RNA SEQUENCING STUDY OF GUT EPITHELIUM IN HUMAN OBESITY by Mcrae, Alison, Silgado, Maria Laura Ricardo, Calderon, Gerardo, Izundegui, Daniel Gonzalez, Yun, Changho, Hashem, Anas, Cifuentes, Lizeth, Campos, Alejandro, Leggett, Cadman L., Simon, Vernadette, Liu, Yuanhuang, Li, Ying, Acosta, Andres

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Regulator of G-protein signaling expression in human intestinal enteroendocrine cells and potential role in satiety hormone secretion in health and obesityResearch in context by Alison N. McRae, Alexander L. Ticho, Yuanhang Liu, Maria Laura Ricardo-Silgado, Nothando N. Mangena, Fauzi Feris Jassir, Daniel Gonzalez-Izundegui, Gerardo Calderon, Fariborz Rakhshan Rohakhtar, Vernadette Simon, Ying Li, Cadman Leggett, Daniela Hurtado, Nicholas LaRusso, Andres J. Acosta

“…Background: Gut L-type enteroendocrine cells (EECs) are intestinal chemosensory cells that secrete satiety hormones GLP-1 and PYY in response to activation of…”
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Regulator of G-protein signaling expression in human intestinal enteroendocrine cells and potential role in satiety hormone secretion in health and obesity by McRae, Alison N., Ticho, Alexander L., Liu, Yuanhang, Ricardo-Silgado, Maria Laura, Mangena, Nothando N., Jassir, Fauzi Feris, Gonzalez-Izundegui, Daniel, Calderon, Gerardo, Rohakhtar, Fariborz Rakhshan, Simon, Vernadette, Li, Ying, Leggett, Cadman, Hurtado, Daniela, LaRusso, Nicholas, Acosta, Andres J.

“…Gut L-type enteroendocrine cells (EECs) are intestinal chemosensory cells that secrete satiety hormones GLP-1 and PYY in response to activation of G-protein…”
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516 UROCORTIN 3 EXPRESSION IN HUMAN ENTEROENDOCRINE CELLS AND CORRELATION WITH PLASMA GLP1 LEVELS IN HUMAN OBESITY by Silgado, Maria Laura Ricardo, Yun, Changho, Mcrae, Alison, Calderon, Gerardo, Izundegui, Daniel Gonzalez, Leggett, Cadman L., Simon, Vernadette, Liu, Yuanhuang, Li, Ying, Acosta, Andres

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Abstract 806: Enhancer deregulation in TET2 -mutant clonal hematopoiesis is associated with increased COVID-19 severity and mortality by Binder, Moritz, Lasho, Terra L., Ismail, Wazim Mohammed, Ben-Crentsil, Nana A., Fernandez, Jenna A., Kim, Minsuk, Geyer, Susan M., Mazzone, Amelia, Finke, Christy M., Mangaonkar, Abhishek A., Lee, Jeong-Heon, Kim, Kwan Hyun, Simon, Vernadette A., Rohakthar, Fariborz Rakhshan, Munankarmy, Amik, Schwager, Susan M., Harrington, Jonathan J., Snyder, Melissa R., Droin, Nathalie M., Solary, Eric, Robertson, Keith D., Wieben, Eric D., Padron, Eric, Chia, Nicholas, Gaspar-Maia, Alexandre, Patnaik, Mrinal M.

“…Abstract Background: COVID-19 causes significant morbidity and mortality, albeit with considerable heterogeneity among affected individuals. It remains unclear…”
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High Throughput Quantitative PCR Using Low-input Samples for mRNA and MicroRNA Gene Expression Analyses by Jang, Jinsung, Kolbert, Christopher, Jen, Jin, Simon, Vernadette

“…Technical advancements in quantitative PCR (qPCR) instrumentation have made it possible to perform gene expression measurements using small sample input to…”
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Noncanonical TRAIL Signaling Promotes Myeloid-Derived Suppressor Cell Abundance and Tumor Growth in CholangiocarcinomaSummary by Emilien J. Loeuillard, Binbin Li, Hannah E. Stumpf, Jingchun Yang, Jessica R. Willhite, Jennifer L. Tomlinson, Fred Rakhshan Rohakhtar, Vernadette A. Simon, Rondell P. Graham, Rory L. Smoot, Haidong Dong, Sumera I. Ilyas

“…Background & Aims: Proapoptotic tumor necrosis factor–related apoptosis-inducing ligand (TRAIL) signaling as a cause of cancer cell death is a well-established…”
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Microarray Analysis of Diurnal and Circadian-Regulated Genes in Arabidopsis by Schaffer, Robert, Landgraf, Jeff, Accerbi, Monica, Simon, Vernadette, Larson, Matt, Wisman, Ellen

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