Search Results - "Simon, U"

The double-edged effects of the corporate venture capital unit's structural autonomy on corporate investors' explorative and exploitative innovation by Lee, Simon U., Park, Gunno, Kang, Jina

“…Although most prior literature on the strategic value of corporate venture capital (CVC) investments has focused solely on its role as an explorative learning…”
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Eosinophilic esophagitis is characterized by a non‐IgE‐mediated food hypersensitivity by Simon, D., Cianferoni, A., Spergel, J. M., Aceves, S., Holbreich, M., Venter, C., Rothenberg, M. E., Terreehorst, I., Muraro, A., Lucendo, A. J., Schoepfer, A., Straumann, A., Simon, H.‐U.

“…Eosinophilic esophagitis (EoE) is a chronic disease characterized clinically by symptoms of esophageal dysfunction and histologically by eosinophil‐predominant…”
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Extracellular DNA traps in allergic, infectious, and autoimmune diseases by Simon, D., Simon, H.‐U., Yousefi, S.

“…Extracellular DNA traps are part of the innate immune response and are seen with many infectious, allergic, and autoimmune diseases. They can be generated by…”
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Evidence of an abnormal epithelial barrier in active, untreated and corticosteroid‐treated eosinophilic esophagitis by Simon, D., Page, B., Vogel, M., Bussmann, C., Blanchard, C., Straumann, A., Simon, H.‐U.

“…Background Eosinophilic esophagitis (EoE) is a chronic, immune/antigen‐mediated disease characterized by symptoms related to esophageal dysfunction and an…”
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Pediatric and adult eosinophilic esophagitis: similarities and differences by Straumann, A., Aceves, S. S., Blanchard, C., Collins, M. H., Furuta, G. T., Hirano, I., Schoepfer, A. M., Simon, D., Simon, H.-U.

“…Early in the 1990s, several case series described adults suffering from dysphagia and children with refractory reflux symptoms, both accompanied by an…”
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Active eosinophilic esophagitis is characterized by epithelial barrier defects and eosinophil extracellular trap formation by Simon, D., Radonjic‐Hösli, S., Straumann, A., Yousefi, S., Simon, H.‐U.

“…Background Eosinophilic esophagitis (EoE) exhibits esophageal dysfunction owing to an eosinophil‐predominant inflammation. Activated eosinophils generate…”
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Precision medicine in allergic disease—food allergy, drug allergy, and anaphylaxis—PRACTALL document of the European Academy of Allergy and Clinical Immunology and the American Academy of Allergy, Asthma and Immunology by Muraro, A., Lemanske, R. F., Castells, M., Torres, M. J., Khan, D., Simon, H.‐U., Bindslev‐Jensen, C., Burks, W., Poulsen, L. K., Sampson, H. A., Worm, M., Nadeau, K. C.

“…This consensus document summarizes the current knowledge on the potential for precision medicine in food allergy, drug allergy, and anaphylaxis under the…”
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Role of Patient-Derived Models of Cancer in Translational Oncology by Idrisova, K F, Simon, H-U, Gomzikova, M O

“…Cancer is a heterogeneous disease. Each individual tumor is unique and characterized by structural, cellular, genetic and molecular features. Therefore,…”
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Anti‐eosinophil activity and clinical efficacy of the CRTH2 antagonist OC000459 in eosinophilic esophagitis by Straumann, A., Hoesli, S., Bussmann, Ch, Stuck, M., Perkins, M., Collins, L. P., Payton, M., Pettipher, R., Hunter, M., Steiner, J., Simon, H.‐U.

“…Background Eosinophilic esophagitis (EoE) is a chronic, Th2‐type inflammatory disease. Chemoattractant receptor‐homologous molecule on Th2 cells (CRTH2) is a…”
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Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps by Morshed, M., Yousefi, S., Stöckle, C., Simon, H.-U., Simon, D.

“…Background Thymic stromal lymphopoietin (TSLP) that is released by epithelial cells upon certain environmental triggers activates cells of the innate and…”
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Evidence for a role of eosinophils in blister formation in bullous pemphigoid by Graauw, E., Sitaru, C., Horn, M., Borradori, L., Yousefi, S., Simon, H.‐U., Simon, D.

“…Background Bullous pemphigoid (BP) is an autoimmune bullous disease of the skin characterized by subepidermal blister formation due to tissue‐bound and…”
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Mn–Na2WO4/SiO2 as catalyst for the oxidative coupling of methane. What is really known? by Arndt, S., Otremba, T., Simon, U., Yildiz, M., Schubert, H., Schomäcker, R.

“…[Display omitted] ► Knowledge on the Mn–Na2WO4/SiO2 was summarized and critically reviewed. ► Stability of the catalyst is proven, which is important because…”
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Monocytes enhance neutrophil‐induced blister formation in an ex vivo model of bullous pemphigoid by Graauw, E., Sitaru, C., Horn, M. P., Borradori, L., Yousefi, S., Simon, D., Simon, H.‐U.

“…Background Lesions of bullous pemphigoid (BP), an autoimmune subepidermal blistering disease characterized by the presence of tissue‐bound and circulating…”
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Life and death partners: apoptosis, autophagy and the cross-talk between them by Eisenberg-Lerner, A, Bialik, S, Simon, H-U, Kimchi, A

“…It is not surprising that the demise of a cell is a complex well-controlled process. Apoptosis, the first genetically programmed death process identified, has…”
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Viable neutrophils release mitochondrial DNA to form neutrophil extracellular traps by Yousefi, S, Mihalache, C, Kozlowski, E, Schmid, I, Simon, H U

“…Neutrophil extracellular traps (NETs) represent extracellular structures able to bind and kill microorganisms. It is believed that they are generated by…”
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A new eosinophilic esophagitis (EoE)‐like disease without tissue eosinophilia found in EoE families by Straumann, A., Blanchard, C., Radonjic‐Hoesli, S., Bussmann, Ch, Hruz, P., Safroneeva, E., Simon, D., Schoepfer, A. M., Simon, H.‐U.

“…Background Eosinophilic esophagitis (EoE) is a rapidly emerging, chronic inflammatory, genetically impacted disease of the esophagus, defined clinically by…”
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Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 by Galluzzi, L, Vitale, I, Abrams, J M, Alnemri, E S, Baehrecke, E H, Blagosklonny, M V, Dawson, T M, Dawson, V L, El-Deiry, W S, Fulda, S, Gottlieb, E, Green, D R, Hengartner, M O, Kepp, O, Knight, R A, Kumar, S, Lipton, S A, Lu, X, Madeo, F, Malorni, W, Mehlen, P, Nuñez, G, Peter, M E, Piacentini, M, Rubinsztein, D C, Shi, Y, Simon, H-U, Vandenabeele, P, White, E, Yuan, J, Zhivotovsky, B, Melino, G, Kroemer, G

“…In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of recommendations for the definition of distinct cell death morphologies and for the…”
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Basophils exhibit antibacterial activity through extracellular trap formation by Yousefi, S., Morshed, M., Amini, P., Stojkov, D., Simon, D., Gunten, S., Kaufmann, T., Simon, H.‐U.

“…Basophils are primarily associated with immunomodulatory functions in allergic diseases and parasitic infections. Recently, it has been demonstrated that both…”
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Frequent sensitization to Candida albicans and profilins in adult eosinophilic esophagitis by Simon, D., Straumann, A., Dahinden, C., Simon, H.‐U.

“…Background Eosinophilic esophagitis (EoE) is often associated with atopic airway and skin diseases. More than 80% of EoE patients are sensitized to aero‐…”
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EAACI IG Biologicals task force paper on the use of biologic agents in allergic disorders by Boyman, O., Kaegi, C., Akdis, M., Bavbek, S., Bossios, A., Chatzipetrou, A., Eiwegger, T., Firinu, D., Harr, T., Knol, E., Matucci, A., Palomares, O., Schmidt‐Weber, C., Simon, H.‐U., Steiner, U. C., Vultaggio, A., Akdis, C. A., Spertini, F.

“…Biologic agents (also termed biologicals or biologics) are therapeutics that are synthesized by living organisms and directed against a specific determinant,…”
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