Search Results - "Simon, Márton A."

Optimization of CFTR gating through the evolution of its extracellular loops by Simon, Márton A, Csanády, László

“…CFTR chloride channel mutations cause the lethal and incurable disease cystic fibrosis (CF). CFTR is activated by phosphorylation, and phosphorylated channels…”
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Molecular pathology of the R117H cystic fibrosis mutation is explained by loss of a hydrogen bond by Simon, Márton A, Csanády, László

“…The phosphorylation-activated anion channel cystic fibrosis transmembrane conductance regulator (CFTR) is gated by an ATP hydrolysis cycle at its two cytosolic…”
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Promiscuity mapping of the S100 protein family using a high-throughput holdup assay by Simon, Márton A., Bartus, Éva, Mag, Beáta, Boros, Eszter, Roszjár, Lea, Gógl, Gergő, Travé, Gilles, Martinek, Tamás A., Nyitray, László

“…S100 proteins are small, typically homodimeric, vertebrate-specific EF-hand proteins that establish Ca 2+ -dependent protein–protein interactions in the intra-…”
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Correction: Optimization of CFTR gating through the evolution of its extracellular loops by Simon, Márton A, Csanády, László

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Estimating the true stability of the prehydrolytic outward-facing state in an ABC protein by Simon, Márton A, Iordanov, Iordan, Szollosi, Andras, Csanády, László

“…CFTR, the anion channel mutated in cystic fibrosis patients, is a model ABC protein whose ATP-driven conformational cycle is observable at single-molecule…”
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High‐throughput competitive fluorescence polarization assay reveals functional redundancy in the S100 protein family by Simon, Márton A., Ecsédi, Péter, Kovács, Gábor M., Póti, Ádám L., Reményi, Attila, Kardos, József, Gógl, Gergő, Nyitray, László

“…The calcium‐binding, vertebrate‐specific S100 protein family consists of 20 paralogs in humans (referred as the S100ome), with several clinically important…”
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Proteomimetic surface fragments distinguish targets by function by Tököli, Attila, Mag, Beáta, Bartus, Éva, Wéber, Edit, Szakonyi, Gerda, Simon, Márton A, Czibula, Ágnes, Monostori, Éva, Nyitray, László, Martinek, Tamás A

“…The fragment-centric design promises a means to develop complex xenobiotic protein surface mimetics, but it is challenging to find locally biomimetic…”
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Understanding impact of δF508 and G551D CFTR mutations on CFTR/PKA-c interaction by Simon, Marton A., Csanady, Laszlo

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