Search Results - "Simon, Layla"

Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells by Ortiz, Rina, Díaz, Jorge, Díaz-Valdivia, Natalia, Martínez, Samuel, Simón, Layla, Contreras, Pamela, Lobos-González, Lorena, Guerrero, Simón, Leyton, Lisette, Quest, Andrew F.G.

“…•PP2 and DST inhibit Src/c-Abl non-receptor tyrosine kinases and thereby reduce phosphorylation of caveolin-1 on tyrosine-14 in B16F10 melanoma…”
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Impact of high fat diet on the sterol regulatory element-binding protein 2 cholesterol pathway in the testicle by Funes, Abi K, Simón, Layla, Colombo, Regina, Avena, María Virginia, Monclús, María, Crescitelli, Julieta, Cabrillana, María E, Conte, María Inés, Cayado, Niubys, Boarelli, Paola, Fornés, Miguel W, Saez Lancellotti, Tania E

“…Abstract Male fertility has been shown to be dependent on cholesterol homeostasis. This lipid is essential for testosterone synthesis and spermatogenesis, but…”
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Mitochondrial Dysfunction and the Glycolytic Switch Induced by Caveolin-1 Phosphorylation Promote Cancer Cell Migration, Invasion, and Metastasis by Díaz-Valdivia, Natalia, Simón, Layla, Díaz, Jorge, Martinez-Meza, Samuel, Contreras, Pamela, Burgos-Ravanal, Renato, Pérez, Viviana I., Frei, Balz, Leyton, Lisette, Quest, Andrew F. G.

“…Cancer cells often display impaired mitochondrial function, reduced oxidative phosphorylation, and augmented aerobic glycolysis (Warburg effect) to fulfill…”
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Extra‐virgin olive oil ameliorates high‐fat diet‐induced seminal and testicular disorders by modulating the cholesterol pathway by Funes, Abi Karenina, Avena, María Virginia, Ibañez, Jorge, Simón, Layla, Ituarte, Leonor, Colombo, Regina, Roldán, Adrián, Conte, María Inés, Monclus, María Ángeles, Boarelli, Paola, Fornés, Miguel Walter, Saez Lancellotti, Tania Estefanía

“…Background Rabbits are sensitive to dietary cholesterol and rapidly develop hypercholesterolemia, leading to prominent subfertility. Sterol regulatory…”
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Antitumor Effects of Resveratrol Opposing Mechanisms of Helicobacter pylori in Gastric Cancer by Trautmann, Daniela, Suazo, Francesca, Torres, Keila, Simón, Layla

“…Gastric cancer is an aggressive and multifactorial disease. ( ) is identified as a significant etiological factor in gastric cancer. Although only a fraction…”
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Bioactive compounds as potential alternative treatments to prevent cancer therapy-induced male infertility by Simón, Layla, Mariotti-Celis, María Salomé

“…About 8-12% of couples experience infertility, with male infertility being the cause in 50% of cases. Several congenital and acquired conditions, including…”
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Inhibition of glycolysis and Src/Akt signaling reduces Caveolin-1-enhanced metastasis by Simón, Layla, Torres, Keila, Contreras, Pamela, Díaz-Valdivia, Natalia, Leyton, Lisette, Quest, Andrew F.G.

“…Metastasis is the leading cause of cancer-related deaths, making the development of novel, more effective therapies imperative to alleviate patient suffering…”
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Effect of Curcumin Consumption on Inflammation and Oxidative Stress in Patients on Hemodialysis: A Literature Review by D'andurain, Javiera, López, Vanessa, Arazo-Rusindo, Migdalia, Tiscornia, Caterina, Aicardi, Valeria, Simón, Layla, Mariotti-Celis, María Salomé

“…Advanced chronic kidney disease (CKD) stages lead to exacerbated inflammation and oxidative stress. Patients with CKD in stage 5 need renal hemodialysis (HD)…”
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The Adipocyte-Macrophage Relationship in Cancer: A Potential Target for Antioxidant Therapy by Sanhueza, Sofía, Simón, Layla, Cifuentes, Mariana, Quest, Andrew F G

“…Obesity has emerged as a major public health concern with a staggering 39% worldwide prevalence as of 2021. Given the magnitude of the problem and considering…”
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Role of the Pro-Inflammatory Tumor Microenvironment in Extracellular Vesicle-Mediated Transfer of Therapy Resistance by Simón, Layla, Sanhueza, Sofía, Gaete-Ramírez, Belén, Varas-Godoy, Manuel, Quest, Andrew F G

“…Advances in our understanding of cancer biology have contributed to generating different treatments to improve the survival of cancer patients. However,…”
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Manchette-acrosome disorders and testicular efficiency decline observed in hypercholesterolemic rabbits are recovered with olive oil enriched diet by Simón, Layla, Funes, Abi K, Monclús, María A, Colombo, Regina, Cabrillana, María E, Saez Lancellotti, Tania E, Fornés, Miguel W

“…High-fat diet is associated with hypercholesterolemia and seminal alterations in White New Zealand rabbits. We have previously reported disorders in the…”
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Phlorotannins: Novel Orally Administrated Bioactive Compounds That Induce Mitochondrial Dysfunction and Oxidative Stress in Cancer by Simón, Layla, Arazo-Rusindo, Migdalia, Quest, Andrew F. G, Mariotti-Celis, María Salomé

“…Mitochondrial dysfunction is an interesting therapeutic target to help reduce cancer deaths, and the use of bioactive compounds has emerged as a novel and safe…”
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Manchette-acrosome disorders during spermiogenesis and low efficiency of seminiferous tubules in hypercholesterolemic rabbit model by Simón, Layla, Funes, Abi K, Yapur, Martín A, Cabrillana, María E, Monclus, María A, Boarelli, Paola V, Vincenti, Amanda E, Saez Lancellotti, Tania E, Fornés, Miguel W

“…Hypercholesterolemia is a marker for several adult chronic diseases. Recently we demonstrated that sub/infertility is also associated to Hypercholesterolemia…”
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Semen quality and sperm function loss by hypercholesterolemic diet was recovered by addition of olive oil to diet in rabbit by Saez Lancellotti, Tania E, Boarelli, Paola V, Romero, Aida A, Funes, Abi K, Cid-Barria, Macarena, Cabrillana, María E, Monclus, María A, Simón, Layla, Vicenti, Amanda E, Fornés, Miguel W

“…Fat increment (0.05% cholesterol, chol) in standard diet promoted a significant increase in serum and sperm membrane chol, which ultimately altered…”
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Pigment epithelium derived factor (PEDF) expression in the male tract of Wistar rats by Conte, Maria Ines, Cabrillana, Maria Eugenia, Saez Lancellotti, Tania Estefania, Simon, Layla, Funes, Abi Karenina, Cayado-Gutiérrez, Niubys, Tagle-Delgado, Matias Gustavo, Vincenti, Amanda Edith, Lopez, Maria Elis, Pietrobon, Elisa Olivia, Fornes, Miguel Walter, Monclus, Maria Angeles

“…Pigment epithelium derived factor (PEDF) expression has been described in many organs as showing neurotrophic, anti-angiogenic, anti-apoptotic,…”
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Curcumin Administration Routes in Breast Cancer Treatment by Mayo, Bianca, Penroz, Silvana, Torres, Keila, Simón, Layla

“…Breast cancer is a public health concern worldwide, characterized by increasing incidence and mortality rates, requiring novel and effective therapeutic…”
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