Search Results - "Simon, Jack H."

Intramuscular Interferon Beta-1A Therapy Initiated during a First Demyelinating Event in Multiple Sclerosis by Jacobs, Lawrence D, Beck, Roy W, Simon, Jack H, Kinkel, R. Phillip, Brownscheidle, Carol M, Murray, Thomas J, Simonian, Nancy A, Slasor, Peter J, Sandrock, Alfred W

“…Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system that most commonly affects women, with an onset typically…”
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International consensus diagnostic criteria for neuromyelitis optica spectrum disorders by Wingerchuk, Dean M, Banwell, Brenda, Bennett, Jeffrey L, Cabre, Philippe, Carroll, William, Chitnis, Tanuja, de Seze, Jérôme, Fujihara, Kazuo, Greenberg, Benjamin, Jacob, Anu, Jarius, Sven, Lana-Peixoto, Marco, Levy, Michael, Simon, Jack H, Tenembaum, Silvia, Traboulsee, Anthony L, Waters, Patrick, Wellik, Kay E, Weinshenker, Brian G

“…Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G…”
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Predictors of long-term outcome in multiple sclerosis patients treated with interferon beta by Bermel, Robert A., You, Xiaojun, Foulds, Pamela, Hyde, Robert, Simon, Jack H., Fisher, Elizabeth, Rudick, Richard A.

“…Objective: To identify early predictors of long‐term outcomes in patients with relapsing–remitting multiple sclerosis (RRMS) treated with intramuscular (IM)…”
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Variants of Multiple Sclerosis by Simon, Jack H., MD, PhD, Kleinschmidt-DeMasters, B.K., MD

“…The classic multiple sclerosis variants including Devic's neuromyelitis optica (NMO), Balo's concentric Sclerosis, Schilder's disease, and Marburg MS are both…”
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MRI and the diagnosis of multiple sclerosis: expanding the concept of "no better explanation" by Charil, Arnaud, Yousry, Tarek A, Rovaris, Marco, Barkhof, Frederik, De Stefano, Nicola, Fazekas, Franz, Miller, David H, Montalban, Xavier, Simon, Jack H, Polman, Chris, Filippi, Massimo

“…Although the diagnosis of multiple sclerosis relies on the demonstration of disease dissemination in space and time, the exclusion of other neurological…”
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Fast multislice mapping of the myelin water fraction using multicompartment analysis of T2 decay at 3T: a preliminary postmortem study by Du, Yiping P, Chu, Renxin, Hwang, Dosik, Brown, Mark S, Kleinschmidt-DeMasters, Bette K, Singel, Debra, Simon, Jack H

“…Quantitative mapping of the myelin water content can provide significant insight into the pathophysiology of several white matter diseases, such as multiple…”
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MRI outcomes in the diagnosis and disease course of multiple sclerosis by Simon, Jack H

“…Despite major advances in MRI, including practical implementations of multiple quantitative MRI methods, the conventional measures of focal, macroscopic…”
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The NAIMS cooperative pilot project: Design, implementation and future directions by Oh, Jiwon, Bakshi, Rohit, Calabresi, Peter A, Crainiceanu, Ciprian, Henry, Roland G, Nair, Govind, Papinutto, Nico, Constable, R Todd, Reich, Daniel S, Pelletier, Daniel, Rooney, William, Schwartz, Daniel, Tagge, Ian, Shinohara, Russell T, Simon, Jack H, Sicotte, Nancy L

“…The North American Imaging in Multiple Sclerosis (NAIMS) Cooperative represents a network of 27 academic centers focused on accelerating the pace of magnetic…”
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MRI monitoring of immunomodulation in relapse-onset multiple sclerosis trials by Barkhof, Frederik, Simon, Jack H., Fazekas, Franz, Rovaris, Marco, Kappos, Ludwig, de Stefano, Nicola, Polman, Chris H., Petkau, John, Radue, Ernst W., Sormani, Maria P., Li, David K., O'Connor, Paul, Montalban, Xavier, Miller, David H., Filippi, Massimo

“…Lesion activity detected on MRI scans has become an accepted surrogate for disease activity in relapsing–remitting multiple sclerosis (MS). Barkhof and…”
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Response to comment on letter for: ‘Prevalence of brain magnetic resonance imaging meeting Barkhof and McDonald criteria for dissemination in space among headache patients’ by Hamilton, Bronwyn, Liu, Syrone, Simon, Jack H, Bourdette, Dennis

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Neuropsychological effects of interferon β-1a in relapsing multiple sclerosis by Fischer, Jill S., Priore, Roger L., Jacobs, Lawrence D., Cookfair, Diane L., Rudick, Richard A., Herndon, Robert M., Richert, John R., Salazar, Andres M., Goodkin, Donald E., Granger, Carl V., Simon, Jack H., Grafman, Jordan H., Lezak, Muriel D., O'Reilly Hovey, Kathleen M., Kawczak Perkins, Katherine, Barilla-Clark, Danielle, Schacter, Mark, Shucard, David W., Davidson, Anna L., Wende, Karl E., Bourdette, Dennis N., Kooijmans-Coutinho, Mariska F.

“…Cognitive dysfunction is common in multiple sclerosis (MS), yet few studies have examined effects of treatment on neuropsychological (NP) performance. To…”
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Interferon β-1a for early multiple sclerosis: CHAMPS trial subgroup analyses by Beck, Roy W., Chandler, Danielle L., Cole, Stephen R., Simon, Jack H., Jacobs, Lawrence D., Kinkel, R. Philip, Selhorst, John B., Rose, John W., Cooper, Joanna A., Rice, George, Murray, Thomas J., Sandrock, Alfred W.

“…The objective of this work was to assess the effect of interferon β‐1a (Avonex®) on the rate of development of clinically definite multiple sclerosis and brain…”
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Frontal Cortex Atrophy Predicts Cognitive Impairment in Multiple Sclerosis by Benedict, Ralph H.B, Bakshi, Rohit, Simon, Jack H, Priore, Roger, Miller, Colleen, Munschauer, Frederick

“…The association between regional measures of cortical atrophy and neuropsychological (NP) dysfunction was studied in 35 multiple sclerosis (MS) patients…”
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Identification of fibers at risk for degeneration by diffusion tractography in patients at high risk for MS after a clinically isolated syndrome by Simon, Jack H., Zhang, Song, Laidlaw, David H., Miller, David E., Brown, Mark, Corboy, John, Bennett, Jeffrey

“…Purpose Focal inflammatory/demyelinating lesions are thought to be the source of Wallerian degeneration or other injury to local, transiting fiber tracts in…”
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Update on multiple sclerosis by Simon, Jack H

“…In this article the basic features of the focal MR imaging lesions and the underlying pathology are reviewed. Next, the diffuse pathology in the…”
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A twin MRI study of size variations in human brain by Pennington, B F, Filipek, P A, Lefly, D, Chhabildas, N, Kennedy, D N, Simon, J H, Filley, C M, Galaburda, A, DeFries, J C

“…Although it is well known that there is considerable variation among individuals in the size of the human brain, the etiology of less extreme individual…”
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Magnetic resonance techniques for the in vivo assessment of multiple sclerosis pathology: Consensus report of the white matter study group by Filippi, Massimo, Falini, Andrea, Arnold, Douglas L., Fazekas, Franz, Gonen, Oded, Simon, Jack H., Dousset, Vincent, Savoiardo, Mario, Wolinsky, Jerry S.

“…On October 9–11, 2003, the third meeting of the White Matter Study Group of the International Society for Magnetic Resonance in Medicine was held in Venice,…”
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Association between immediate initiation of intramuscular interferon beta-1a at the time of a clinically isolated syndrome and long-term outcomes: a 10-year follow-up of the Controlled High-Risk Avonex Multiple Sclerosis Prevention Study in Ongoing Neurological Surveillance by Kinkel, R Philip, Dontchev, Mariya, Kollman, Craig, Skaramagas, Thomai T, O'Connor, Paul W, Simon, Jack H

“…To determine whether immediate initiation of treatment at the time of a clinically isolated syndrome in patients at high risk for clinically definite multiple…”
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MRI in multiple sclerosis by Simon, Jack H

“…MRI provides multiple uses and applications in multiple sclerosis(MS). The basic features of the MRI-detected lesions, including the underlying pathology, are…”
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From enhancing lesions to brain atrophy in relapsing MS by Simon, Jack H

“…Based on observations from MR imaging studies, the natural history of the MS lesion appears to be progression from an acute enhancing lesion, corresponding to…”
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