Search Results - "Simon, Jack H"
-
1
Intramuscular Interferon Beta-1A Therapy Initiated during a First Demyelinating Event in Multiple Sclerosis
Published in The New England journal of medicine (28-09-2000)“…Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system that most commonly affects women, with an onset typically…”
Get full text
Journal Article -
2
International consensus diagnostic criteria for neuromyelitis optica spectrum disorders
Published in Neurology (14-07-2015)“…Neuromyelitis optica (NMO) is an inflammatory CNS syndrome distinct from multiple sclerosis (MS) that is associated with serum aquaporin-4 immunoglobulin G…”
Get full text
Journal Article Conference Proceeding -
3
Predictors of long-term outcome in multiple sclerosis patients treated with interferon beta
Published in Annals of neurology (01-01-2013)“…Objective: To identify early predictors of long‐term outcomes in patients with relapsing–remitting multiple sclerosis (RRMS) treated with intramuscular (IM)…”
Get full text
Journal Article -
4
Variants of Multiple Sclerosis
Published in Neuroimaging clinics of North America (01-11-2008)“…The classic multiple sclerosis variants including Devic's neuromyelitis optica (NMO), Balo's concentric Sclerosis, Schilder's disease, and Marburg MS are both…”
Get full text
Journal Article -
5
MRI and the diagnosis of multiple sclerosis: expanding the concept of "no better explanation"
Published in Lancet neurology (01-10-2006)“…Although the diagnosis of multiple sclerosis relies on the demonstration of disease dissemination in space and time, the exclusion of other neurological…”
Get more information
Journal Article -
6
Fast multislice mapping of the myelin water fraction using multicompartment analysis of T2 decay at 3T: a preliminary postmortem study
Published in Magnetic resonance in medicine (01-11-2007)“…Quantitative mapping of the myelin water content can provide significant insight into the pathophysiology of several white matter diseases, such as multiple…”
Get full text
Journal Article -
7
MRI outcomes in the diagnosis and disease course of multiple sclerosis
Published in Handbook of clinical neurology (2014)“…Despite major advances in MRI, including practical implementations of multiple quantitative MRI methods, the conventional measures of focal, macroscopic…”
Get more information
Journal Article -
8
The NAIMS cooperative pilot project: Design, implementation and future directions
Published in Multiple sclerosis (01-11-2018)“…The North American Imaging in Multiple Sclerosis (NAIMS) Cooperative represents a network of 27 academic centers focused on accelerating the pace of magnetic…”
Get full text
Journal Article -
9
MRI monitoring of immunomodulation in relapse-onset multiple sclerosis trials
Published in Nature reviews. Neurology (01-01-2012)“…Lesion activity detected on MRI scans has become an accepted surrogate for disease activity in relapsing–remitting multiple sclerosis (MS). Barkhof and…”
Get full text
Journal Article -
10
-
11
Neuropsychological effects of interferon β-1a in relapsing multiple sclerosis
Published in Annals of neurology (01-12-2000)“…Cognitive dysfunction is common in multiple sclerosis (MS), yet few studies have examined effects of treatment on neuropsychological (NP) performance. To…”
Get full text
Journal Article -
12
Interferon β-1a for early multiple sclerosis: CHAMPS trial subgroup analyses
Published in Annals of neurology (01-04-2002)“…The objective of this work was to assess the effect of interferon β‐1a (Avonex®) on the rate of development of clinically definite multiple sclerosis and brain…”
Get full text
Journal Article -
13
Frontal Cortex Atrophy Predicts Cognitive Impairment in Multiple Sclerosis
Published in The journal of neuropsychiatry and clinical neurosciences (2002)“…The association between regional measures of cortical atrophy and neuropsychological (NP) dysfunction was studied in 35 multiple sclerosis (MS) patients…”
Get full text
Journal Article -
14
Identification of fibers at risk for degeneration by diffusion tractography in patients at high risk for MS after a clinically isolated syndrome
Published in Journal of magnetic resonance imaging (01-11-2006)“…Purpose Focal inflammatory/demyelinating lesions are thought to be the source of Wallerian degeneration or other injury to local, transiting fiber tracts in…”
Get full text
Journal Article -
15
Update on multiple sclerosis
Published in The Radiologic clinics of North America (01-01-2006)“…In this article the basic features of the focal MR imaging lesions and the underlying pathology are reviewed. Next, the diffuse pathology in the…”
Get more information
Journal Article -
16
A twin MRI study of size variations in human brain
Published in Journal of cognitive neuroscience (01-01-2000)“…Although it is well known that there is considerable variation among individuals in the size of the human brain, the etiology of less extreme individual…”
Get more information
Journal Article -
17
Magnetic resonance techniques for the in vivo assessment of multiple sclerosis pathology: Consensus report of the white matter study group
Published in Journal of magnetic resonance imaging (01-06-2005)“…On October 9–11, 2003, the third meeting of the White Matter Study Group of the International Society for Magnetic Resonance in Medicine was held in Venice,…”
Get full text
Journal Article -
18
Association between immediate initiation of intramuscular interferon beta-1a at the time of a clinically isolated syndrome and long-term outcomes: a 10-year follow-up of the Controlled High-Risk Avonex Multiple Sclerosis Prevention Study in Ongoing Neurological Surveillance
Published in Archives of neurology (Chicago) (01-02-2012)“…To determine whether immediate initiation of treatment at the time of a clinically isolated syndrome in patients at high risk for clinically definite multiple…”
Get more information
Journal Article -
19
MRI in multiple sclerosis
Published in Physical medicine and rehabilitation clinics of North America (01-05-2005)“…MRI provides multiple uses and applications in multiple sclerosis(MS). The basic features of the MRI-detected lesions, including the underlying pathology, are…”
Get more information
Journal Article -
20
From enhancing lesions to brain atrophy in relapsing MS
Published in Journal of neuroimmunology (01-07-1999)“…Based on observations from MR imaging studies, the natural history of the MS lesion appears to be progression from an acute enhancing lesion, corresponding to…”
Get full text
Journal Article