Search Results - "Simon, JH"

Characterization of putative interneurons in the myenteric plexus of human colon by Humenick, Adam, Chen, Bao Nan, Wattchow, David A., Zagorodnyuk, Vladimir P., Dinning, Phil G., Spencer, Nick J., Costa, Marcello, Brookes, Simon J. H.

“…Background The enteric nervous system contains multiple classes of neurons, distinguishable by morphology, immunohistochemical markers, and projections;…”
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The human enteric nervous system. Historical and modern advances. Collaboration between science and surgery by Wattchow, David A, Smolilo, David, Hibberd, Tim, Spencer, Nick J, Brookes, Simon JH, De Giorgio, Roberto, Heitmann, Paul T, Costa, Marcello, Dinning, Phil G.

“…Background There are considerable advantages and opportunities for surgeons and trainee surgeons in conducting a period of research allied with basic…”
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Rectal prolapse in Winnie mice with spontaneous chronic colitis: changes in intrinsic and extrinsic innervation of the rectum by Rahman, Ahmed A., Robinson, Ainsley M., Brookes, Simon J. H., Eri, Rajaraman, Nurgali, Kulmira

“…Rectal prolapse is associated with diminished anal sensitivity and rectal motor activity. Both sensory and motor functions are controlled by the extrinsic and…”
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Measurement of strains experienced by viscerofugal nerve cell bodies during mechanosensitive firing using digital image correlation by Palmer, Gwen, Hibberd, Timothy J, Roose, Tiina, Brookes, Simon J H, Taylor, Mark

“…Mechanosensory neurons detect physical events in the local environments of the tissues that they innervate. Studies of mechanosensitivity of neurons or nerve…”
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A Previously Undescribed Coronavirus Associated with Respiratory Disease in Humans by Ron A. M. Fouchier, Hartwig, Nico G., Bestebroer, Theo M., Niemeyer, Berend, de Jong, Jan C., Simon, James H., Albert D. M. E. Osterhaus, Palese, Peter

“…The etiology of acute respiratory tract illnesses is sometimes unclear due to limitations of diagnostic tests or the existence of as-yet-unidentified…”
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Characterization of the colonic response to bisacodyl in children with treatment‐refractory constipation by Heitmann, Paul T., Wiklendt, Lukasz, Thapar, Nikhil, Borrelli, Osvaldo, Di Lorenzo, Carlo, Yacob, Desalegn T., Baaleman, Desiree F., Vriesman, Mana H., Nurko, Samuel, El‐Chammas, Khalil, Kaul, Ajay, Benninga, Marc A., Koppen, Ilan J.N., Wattchow, David A., Brookes, Simon J.H., Dinning, Phil G.

“…Background Colonic manometry with intraluminal bisacodyl infusion can be used to assess colonic neuromuscular function in children with treatment‐refractory…”
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Delta-8, a Cannabis-Derived Tetrahydrocannabinol Isomer: Evaluating Case Report Data in the Food and Drug Administration Adverse Event Reporting System (FAERS) Database by Simon, Teresa A, Simon, John H, Heaning, Erin G, Gomez-Caminero, Andres, Marcu, Jahan P

“…The aim of this study was to characterize the frequency of adverse effects where delta-8 tetrahydrocannabinol (D8-THC) was identified as a possible suspect…”
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Selective coexpression of synaptic proteins, [alpha]-synuclein, cysteine string protein-[alpha], synaptophysin, synaptotagmin-1, and synaptobrevin-2 in vesicular acetylcholine transporter-immunoreactive axons in the guinea pig ileum by Sharrad, Dale F, Gai, Wei-Ping, Brookes, Simon J.H

“…Parkinson's disease is a neurodegenerative disorder characterized by Lewy bodies and neurites composed mainly of the presynaptic protein [alpha]-synuclein…”
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Neurochemical characterization of extrinsic nerves in myenteric ganglia of the guinea pig distal colon by Chen, Bao Nan, Sharrad, Dale F., Hibberd, Timothy J., Zagorodnyuk, Vladimir P., Costa, Marcello, Brookes, Simon J.H.

“…ABSTRACT Extrinsic nerves to the gut influence the absorption of water and electrolytes and expulsion of waste contents, largely via regulation of enteric…”
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Standardized MR imaging protocol for multiple sclerosis : Consortium of MS centers consensus guidelines by SIMON, J. H, LI, D, WOLINSKY, J. S, TRABOULSEE, A, COYLE, P. K, ARNOLD, D. L, BARKHOF, F, FRANK, J. A, GROSSMAN, R, PATY, D. W, RADUE, E. W

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Identification of Medium/High-Threshold Extrinsic Mechanosensitive Afferent Nerves to the Gastrointestinal Tract by Song, Xingyun, Chen, Bao Nan, Zagorodnyuk, Vladimir P, Lynn, Penny A, Blackshaw, L. Ashley, Grundy, David, Brunsden, Alan M, Costa, Marcello, Brookes, Simon J.H

“…Background & Aims Large distentions reliably evoke sensation from the noninflamed, nonischemic bowel, but the specialized afferent axonal structures…”
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Neural mechanisms of peristalsis in the isolated rabbit distal colon: a neuromechanical loop hypothesis by Dinning, Phil G, Wiklendt, Lukasz, Omari, Taher, Arkwright, John W, Spencer, Nick J, Brookes, Simon J H, Costa, Marcello

“…Propulsive contractions of circular muscle are largely responsible for the movements of content along the digestive tract. Mechanical and electrophysiological…”
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Intramuscular Interferon Beta-1A Therapy Initiated during a First Demyelinating Event in Multiple Sclerosis by Jacobs, Lawrence D, Beck, Roy W, Simon, Jack H, Kinkel, R. Phillip, Brownscheidle, Carol M, Murray, Thomas J, Simonian, Nancy A, Slasor, Peter J, Sandrock, Alfred W

“…Multiple sclerosis is a chronic, inflammatory, demyelinating disease of the central nervous system that most commonly affects women, with an onset typically…”
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Proton (fat/water) chemical shift imaging in medical magnetic resonance imaging. Current status by Simon, J H, Szumowski, J

“…Fat/water CSI has recently been transformed from an experimental method to a routine clinical MRI approach, particularly for evaluating paramagnetic contrast…”
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MRI T2 lesion burden in multiple sclerosis : A plateauing relationship with clinical disability by LI, D. K. B, HELD, U, WOLINSKY, J. S, FILIPPI, M, PETKAU, J, DAUMER, M, BARKHOF, F, FAZEKAS, F, FRANK, J. A, KAPPOS, L, MILLER, D. H, SIMON, J. H

“…Previous studies have shown only modest correlation between multiple sclerosis (MS) lesions on MRI and clinical disability. To investigate the relationship…”
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Eight-year follow-up study of brain atrophy in patients with MS by FISHER, E, RUDICK, R. A, SIMONIAN, N. A, SIMON, J. H, CUTTER, G, BAIER, M, LEE, J.-C, MILLER, D, WEINSTOCK-GUTTMAN, B, MASS, M. K, DOUGHERTY, D. S

“…To characterize whole-brain atrophy in relapsing-remitting MS (RRMS) patients over an 8-year period. The specific goals of this study were to determine if…”
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Benefit of interferon beta-1a on MSFC progression in secondary progressive MS by Cohen, J A, Cutter, G R, Fischer, J S, Goodman, A D, Heidenreich, F R, Kooijmans, M F, Sandrock, A W, Rudick, R A, Simon, J H, Simonian, N A, Tsao, E C, Whitaker, J N

“…Interferon beta-1a (IFNbeta-1a, Avonex) is efficacious in relapsing forms of MS. Studies of other IFNbeta preparations in secondary progressive MS (SPMS)…”
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Mechanotransduction and chemosensitivity of two major classes of bladder afferents with endings in the vicinity to the urothelium by Zagorodnyuk, Vladimir P., Brookes, Simon J. H., Spencer, Nick J., Gregory, Sarah

“…The guinea pig bladder is innervated by at least five distinct major classes of extrinsic sensory neurons. In this study, we have examined the mechanisms of…”
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Properties of the major classes of mechanoreceptors in the guinea pig bladder by Zagorodnyuk, Vladimir P., Gibbins, Ian L., Costa, Marcello, Brookes, Simon J. H., Gregory, Sarah J.

“…Sensory neurons represent an attractive target for pharmacological treatment of various bladder disorders. However the properties of major classes of…”
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Ten-year follow-up of the ‘minimal MRI lesion’ subgroup from the original CHAMPS Multiple Sclerosis Prevention Trial by Simon, JH, Kinkel, RP, Kollman, C, O’Connor, P, Fisher, E, You, X, Hyde, R

“…Background: Patients with clinically isolated syndrome (CIS) and characteristic magnetic resonance imaging (MRI) lesions are at high risk for multiple…”
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