Search Results - "Simon, J."
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Structural Analysis of Molecular Materials Using the Pair Distribution Function
Published in Chemical reviews (12-01-2022)“…This is a review of atomic pair distribution function (PDF) analysis as applied to the study of molecular materials. The PDF method is a powerful approach to…”
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2
Silencing Neurons: Tools, Applications, and Experimental Constraints
Published in Neuron (Cambridge, Mass.) (02-08-2017)“…Reversible silencing of neuronal activity is a powerful approach for isolating the roles of specific neuronal populations in circuit dynamics and behavior. In…”
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Using lanthanide ions in molecular bioimaging
Published in Chemical Society reviews (21-07-2015)“…Trivalent lanthanide ions offer remarkable opportunities in the design of bioimaging agents: this review presents an accessible discussion of their application…”
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4
Unlocking the potential of lignocellulosic biomass through plant science
Published in The New phytologist (01-03-2016)“…1366 I. 1366 II. 1367 III. 1368 IV. 1368 V. 1369 VI. 1370 VII. 1372 VIII. 1372 IX. 1376 X. 1377 1377 References 1377 SUMMARY: The aim of producing sustainable…”
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Double-strand break repair: 53BP1 comes into focus
Published in Nature reviews. Molecular cell biology (01-01-2014)“…Key Points p53-binding protein 1 (53BP1) is a crucial component of DNA double-strand break (DSB) signalling and repair in mammalian cells. It is recruited to…”
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Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
Published in Molecular cell (24-08-2012)“…DNA double-strand breaks (DSBs) are highly toxic lesions that can drive genetic instability. To preserve genome integrity, organisms have evolved several DSB…”
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The rise of the X-ray atomic pair distribution function method: a series of fortunate events
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (17-06-2019)“…The atomic pair distribution function (PDF) technique is a powerful approach to gain quantitative insight into the structure of materials where the structural…”
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Sotatercept for the Treatment of Pulmonary Arterial Hypertension
Published in The New England journal of medicine (01-04-2021)“…Patients with pulmonary arterial hypertension were randomly assigned to receive sotatercept at a dose of 0.3 mg per kilogram or 0.7 mg per kilogram or placebo,…”
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Mitogen-activated protein kinases in innate immunity
Published in Nature reviews. Immunology (01-09-2013)“…Key Points Mitogen-activated protein kinases (MAPKs) in innate immune cells are activated by a range of pattern recognition receptors, of which the best…”
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European perspectives on efforts to reduce antimicrobial usage in food animal production
Published in Irish Veterinary Journal (27-01-2020)“…New regulations on veterinary medicines and medicated feed will substantially influence antimicrobial prescribing and usage throughout Europe into the future…”
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Mechanisms of Oncogene-Induced Replication Stress: Jigsaw Falling into Place
Published in Cancer discovery (01-05-2018)“…Oncogene activation disturbs cellular processes and accommodates a complex landscape of changes in the genome that contribute to genomic instability, which…”
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Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1
Published in Journal of the American Chemical Society (05-11-2014)“…The efficient, site-specific introduction of unnatural amino acids into proteins in mammalian cells is an outstanding challenge in realizing the potential of…”
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13
Enhancement of the superconducting transition temperature of FeSe by intercalation of a molecular spacer layer
Published in Nature materials (01-01-2013)“…Altering the composition of the spacer layers present in iron-based superconductors is one strategy for increasing the temperature below which they…”
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14
Molecular interaction and inhibition of SARS-CoV-2 binding to the ACE2 receptor
Published in Nature communications (11-09-2020)“…Study of the interactions established between the viral glycoproteins and their host receptors is of critical importance for a better understanding of virus…”
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Nature of Activated Manganese Oxide for Oxygen Evolution
Published in Journal of the American Chemical Society (02-12-2015)“…Electrodeposited manganese oxide films (MnOx) are promising stable oxygen evolution catalysts. They are able to catalyze the oxygen evolution reaction in…”
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The role of bioimpedance and biomarkers in helping to aid clinical decision-making of volume assessments in dialysis patients
Published in Kidney international (01-09-2014)“…Bioimpedance analysis (BIA) derives two main pieces of information--total tissue fluid content, which when referring to the whole patient is equivalent to the…”
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Mechanisms of DNA–protein crosslink repair
Published in Nature reviews. Molecular cell biology (01-09-2017)“…Key Points Covalent DNA–protein crosslinks (DPCs) are highly toxic DNA lesions that are induced by widely used classes of chemotherapeutics and also by various…”
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Diagnosis of pulmonary hypertension
Published in The European respiratory journal (01-01-2019)“…A revised diagnostic algorithm provides guidelines for the diagnosis of patients with suspected pulmonary hypertension, both prior to and following referral to…”
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STDP-based spiking deep convolutional neural networks for object recognition
Published in Neural networks (01-03-2018)“…Previous studies have shown that spike-timing-dependent plasticity (STDP) can be used in spiking neural networks (SNN) to extract visual features of low or…”
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SURFACE DENSITY EFFECTS IN QUENCHING: CAUSE OR EFFECT?
Published in The Astrophysical journal (10-12-2016)“…ABSTRACT There are very strong observed correlations between the specific star formation rates (sSFRs) of galaxies and their mean surface mass densities, , as…”
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