Search Results - "Simon, J S"

A pilot study using metagenomic sequencing of the sputum microbiome suggests potential bacterial biomarkers for lung cancer by Cameron, Simon J S, Lewis, Keir E, Huws, Sharon A, Hegarty, Matthew J, Lewis, Paul D, Pachebat, Justin A, Mur, Luis A J

“…Lung cancer (LC) is the most prevalent cancer worldwide, and responsible for over 1.3 million deaths each year. Currently, LC has a low five year survival…”
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Visible-Light Photo-Arbuzov Reaction of Aryl Bromides and Trialkyl Phosphites Yielding Aryl Phosphonates by Shaikh, Rizwan S, Düsel, Simon J. S, König, Burkhard

“…Aryl phosphonates are functional groups frequently found in pharmaceutical and crop protection agents. For their synthesis via C–P bond formation typically…”
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Visible-Light-Mediated Nitration of Protected Anilines by Düsel, Simon J. S, König, Burkhard

“…The photocatalytic nitration of protected anilines proceeds with riboflavin tetraacetate as an organic photoredox catalyst. Sodium nitrite serves as the NO2…”
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Photocatalytic Oxidative Iodination of Electron‐Rich Arenes by Narobe, Rok, Düsel, Simon J. S., Iskra, Jernej, König, Burkhard

“…A visible‐light‐mediated oxidative iodination of electron‐rich arenes has been developed. 2.5 mol% of unsubstituted anthraquinone as photocatalyst were used in…”
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Evaluation of Direct from Sample Metabolomics of Human Feces Using Rapid Evaporative Ionization Mass Spectrometry by Cameron, Simon J. S, Alexander, James L, Bolt, Frances, Burke, Adam, Ashrafian, Hutan, Teare, Julian, Marchesi, Julian R, Kinross, James, Li, Jia V, Takáts, Zoltán

“…Mass spectrometry is a powerful tool in the investigation of the human fecal metabolome. However, current approaches require time-consuming sample preparation,…”
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Postoperative ileus—An ongoing conundrum by Wattchow, David, Heitmann, Paul, Smolilo, David, Spencer, Nick J., Parker, Dominic, Hibberd, Timothy, Brookes, Simon S. J., Dinning, Phil G., Costa, Marcello

“…Background Postoperative ileus is common and is a major clinical problem. It has been widely studied in patients and in experimental models in laboratory…”
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Participants in the Trans-Antarctic Winter Traverse Expedition Showed Increased Bacterial Load and Diversity in Saliva but Maintained Individual Differences within Stool Microbiota and Across Metabolite Fingerprints by Cameron, Simon J S, Edwards, Arwyn, Lambert, Robert J, Stroud, Mike, Mur, Luis A J

“…Understanding the impact of long-term physiological and environmental stress on the human microbiota and metabolome may be important for the success of space…”
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Metagenomic Sequencing of the Chronic Obstructive Pulmonary Disease Upper Bronchial Tract Microbiome Reveals Functional Changes Associated with Disease Severity by Cameron, Simon J S, Lewis, Keir E, Huws, Sharon A, Lin, Wanchang, Hegarty, Matthew J, Lewis, Paul D, Mur, Luis A J, Pachebat, Justin A

“…Chronic Obstructive Pulmonary Disease (COPD) is a major source of mortality and morbidity worldwide. The microbiome associated with this disease may be an…”
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Sample Preparation Free Mass Spectrometry Using Laser-Assisted Rapid Evaporative Ionization Mass Spectrometry: Applications to Microbiology, Metabolic Biofluid Phenotyping, and Food Authenticity by Cameron, Simon J. S, Perdones-Montero, Alvaro, Van Meulebroek, Lieven, Burke, Adam, Alexander-Hardiman, Kate, Simon, Daniel, Schaffer, Richard, Balog, Julia, Karancsi, Tamas, Rickards, Tony, Rebec, Monica, Stead, Sara, Vanhaecke, Lynn, Takáts, Zoltán

“…Mass spectrometry has established itself as a powerful tool in the chemical, biological, medical, environmental, and agricultural fields. However, experimental…”
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The human salivary microbiome exhibits temporal stability in bacterial diversity by Cameron, Simon J. S., Huws, Sharon A., Hegarty, Matthew J., Smith, Daniel P. M., Mur, Luis A. J.

“…The temporal variability of the human microbiome may be an important factor in determining its relationship with health and disease. In this study, the saliva…”
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Automated High-Throughput Identification and Characterization of Clinically Important Bacteria and Fungi using Rapid Evaporative Ionization Mass Spectrometry by Bolt, Frances, Cameron, Simon J. S., Karancsi, Tamas, Simon, Daniel, Schaffer, Richard, Rickards, Tony, Hardiman, Kate, Burke, Adam, Bodai, Zsolt, Perdones-Montero, Alvaro, Rebec, Monica, Balog, Julia, Takats, Zoltan

“…Rapid evaporative ionization mass spectrometry (REIMS) has been shown to quickly and accurately speciate microorganisms based upon their species-specific lipid…”
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Human Milk from Tandem Feeding Dyads Does Not Differ in Metabolite and Metataxonomic Features When Compared to Single Nursling Dyads under Six Months of Age by Shenker, Natalie S, Perdones-Montero, Alvaro, Burke, Adam, Stickland, Sarah, McDonald, Julie A K, Cameron, Simon J S

“…Given the long-term advantages of exclusive breastfeeding to infants and their mothers, there is both an individual and public health benefit to its promotion…”
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The effects of loperamide on excitatory and inhibitory neuromuscular function in the human colon by Heitmann, Paul T., Keightley, Lauren, Wiklendt, Lukasz, Wattchow, David A., Brookes, Simon S.J., Spencer, Nicholas J., Costa, Marcello, Dinning, Phil G.

“…Background In most animal species, opioids alter colonic motility via the inhibition of excitatory enteric motor neurons. The mechanisms by which opioids alter…”
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Off-Colony Screening of Biosynthetic Libraries by Rapid Laser-Enabled Mass Spectrometry by Gowers, Glen-Oliver F, Cameron, Simon J. S, Perdones-Montero, Alvaro, Bell, David, Chee, Soo Mei, Kern, Marcelo, Tew, David, Ellis, Tom, Takáts, Zoltan

“…By leveraging advances in DNA synthesis and molecular cloning techniques, synthetic biology increasingly makes use of large construct libraries to explore…”
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Association of a polymorphism in the indoleamine- 2,3-dioxygenase gene and interferon-α-induced depression in patients with chronic hepatitis C by Smith, A K, Simon, J S, Gustafson, E L, Noviello, S, Cubells, J F, Epstein, M P, Devlin, D J, Qiu, P, Albrecht, J K, Brass, C A, Sulkowski, M S, McHutchinson, J G, Miller, A H

“…Interferon (IFN)-α treatment for infectious diseases and cancer is associated with significant depressive symptoms that can limit therapeutic efficacy…”
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Orientation of SecA and SecB in Complex, Derived from Disulfide Cross-Linking by YUYING SUO, HARDY, Simon J. S, RANDALL, Linda L

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Stoichiometry of SecYEG in the active translocase of Escherichia coli varies with precursor species by Mao, Chunfeng, Cheadle, Carl E., Hardy, Simon J. S., Lilly, Angela A., Suo, Yuying, Gari, Raghavendar Reddy Sanganna, King, Gavin M., Randall, Linda L.

“…We have established a reconstitution system for the translocon SecYEG in proteoliposomes in which 55% of the accessible translocons are active. This level…”
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Coupled cryoconite ecosystem structure–function relationships are revealed by comparing bacterial communities in alpine and Arctic glaciers by Edwards, Arwyn, Mur, Luis A.J., Girdwood, Susan E., Anesio, Alexandre M., Stibal, Marek, Rassner, Sara M.E., Hell, Katherina, Pachebat, Justin A., Post, Barbara, Bussell, Jennifer S., Cameron, Simon J.S., Griffith, Gareth Wyn, Hodson, Andrew J., Sattler, Birgit

“…Abstract Cryoconite holes are known as foci of microbial diversity and activity on polar glacier surfaces, but are virtually unexplored microbial habitats in…”
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Toward Delineating the Structure and Function of the Particulate Methane Monooxygenase from Methanotrophic Bacteria by Chan, Sunney I, Chen, Kelvin H.-C, Yu, Steve S.-F, Chen, Chang-Li, Kuo, Simon S.-J

“…The particulate methane monooxygenase (pMMO) is a complex membrane protein complex that has been difficult to isolate and purify for biochemical and…”
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Characterization of the rumen lipidome and microbiome of steers fed a diet supplemented with flax and echium oil by Huws, Sharon Ann, Kim, Eun Jun, Cameron, Simon J. S., Girdwood, Susan E., Davies, Lynfa, Tweed, John, Vallin, Hannah, Scollan, Nigel David

“…Summary Developing novel strategies for improving the fatty acid composition of ruminant products relies upon increasing our understanding of rumen bacterial…”
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