Search Results - "Simon, Glenn C."
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FIP3-endosome-dependent formation of the secondary ingression mediates ESCRT-III recruitment during cytokinesis
Published in Nature cell biology (01-10-2012)“…The final cytokinesis event involves severing of the connecting intercellular bridge (ICB) between daughter cells. FIP3-positive recycling endosomes (FIP3…”
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Mechanisms regulating targeting of recycling endosomes to the cleavage furrow during cytokinesis
Published in Biochemical Society transactions (01-06-2008)“…Recently, recycling endosomes have emerged as a key components required for the successful completion of cytokinesis. Furthermore, FIP3 (family of…”
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Functional complexity of the axonal growth cone: a proteomic analysis
Published in PloS one (27-02-2012)“…The growth cone, the tip of the emerging neurite, plays a crucial role in establishing the wiring of the developing nervous system. We performed an extensive…”
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The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis
Published in Molecular biology of the cell (01-02-2005)“…An integral part of cell division is the separation of daughter cells via cytokinesis. There is now good evidence that the completion of cytokinesis requires…”
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Sequential Cyk-4 binding to ECT2 and FIP3 regulates cleavage furrow ingression and abscission during cytokinesis
Published in The EMBO journal (09-07-2008)“…Cytokinesis is a highly regulated and dynamic event that involves the reorganization of the cytoskeleton and membrane compartments. Recently, FIP3 has been…”
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Identification of Rab11 as a small GTPase binding protein for the Evi5 oncogene
Published in Proceedings of the National Academy of Sciences - PNAS (23-01-2007)“…The Evi5 oncogene has recently been shown to regulate the stability and accumulation of critical G₁ cell cycle factors including Emi1, an inhibitor of the…”
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Molecular characterization of Rab11-FIP3 binding to ARF GTPases
Published in European journal of cell biology (01-08-2007)“…Rab11-FIP3 is a Rab11-binding protein that has been implicated in regulating cytokinesis in mammalian cells. FIP3 functions by simultaneously interacting with…”
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The role of FIP3-dependent endosome transport during cytokinesis
Published in Communicative & integrative biology (01-10-2008)“…Mitosis is a complex cellular process that is completed by the final abscission step called cytokinesis. The many roles of cytoskeletal proteins in animal cell…”
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Endothelial cell adhesion to soluble vascular endothelial growth factor receptor‐1 triggers a cell dynamic and angiogenic phenotype
Published in The FASEB journal (01-02-2014)“…The aim of this study was to identify the molecular signals produced in human endothelial cells (ECs) by the interaction of α5β31 integrin with soluble…”
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Up-regulation of MUC18 in airway epithelial cells by IL-13: implications in bacterial adherence
Published in American journal of respiratory cell and molecular biology (01-05-2011)“…Airway bacterial infections are a major problem in lung diseases, including asthma, chronic obstructive pulmonary disease (COPD), and cystic fibrosis…”
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The FIP3-Rab11 Protein Complex Regulates Recycling Endosome Targeting to the Cleavage Furrow during Late CytokinesisD⃞V
Published in Molecular biology of the cell (01-02-2005)“…An integral part of cell division is the separation of daughter cells via cytokinesis. There is now good evidence that the completion of cytokinesis requires…”
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Journal Article -
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Endosomes and mitosis: FIP3-associated vesicle delivery during cytokinesis
Published 01-01-2008“…Cytokinesis is a highly regulated event that involves many different cellular pathways. Two distinct processes play an important role during cytokinesis:…”
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Dissertation