Search Results - "Simon, E."

Early prediction of autoimmune (type 1) diabetes by Regnell, Simon E., Lernmark, Åke

“…Underlying type 1 diabetes is a genetic aetiology dominated by the influence of specific HLA haplotypes involving primarily the class II DR-DQ region. In…”
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Fluorescent small organic probes for biosensing by Tian, Xue, Murfin, Lloyd C, Wu, Luling, Lewis, Simon E, James, Tony D

“…Small-molecule based fluorescent probes are increasingly important for the detection and imaging of biological signaling molecules due to their simplicity,…”
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Human Genetics: The Evolving Story of FOXP2 by Fisher, Simon E.

“…FOXP2 mutations cause a speech and language disorder, raising interest in potential roles of this gene in human evolution. A new study re-evaluates genomic…”
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An optimized electroporation approach for efficient CRISPR/Cas9 genome editing in murine zygotes by Tröder, Simon E, Ebert, Lena K, Butt, Linus, Assenmacher, Sonja, Schermer, Bernhard, Zevnik, Branko

“…Electroporation of zygotes represents a rapid alternative to the elaborate pronuclear injection procedure for CRISPR/Cas9-mediated genome editing in mice…”
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Applications of biocatalytic arene ipso,ortho cis-dihydroxylation in synthesis by Lewis, Simon E

“…The dearomatising dihydroxylation of aromatic molecules mediated by arene dioxygenase enzymes can provide cyclohexadiene-diols that are versatile starting…”
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ADAR1 averts fatal type I interferon induction by ZBP1 by Jiao, Huipeng, Wachsmuth, Laurens, Wolf, Simone, Lohmann, Juliane, Nagata, Masahiro, Kaya, Göksu Gökberk, Oikonomou, Nikos, Kondylis, Vangelis, Rogg, Manuel, Diebold, Martin, Tröder, Simon E., Zevnik, Branko, Prinz, Marco, Schell, Christoph, Young, George R., Kassiotis, George, Pasparakis, Manolis

“…Mutations of the ADAR1 gene encoding an RNA deaminase cause severe diseases associated with chronic activation of type I interferon (IFN) responses, including…”
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Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria by Korwitz, Anne, Merkwirth, Carsten, Richter-Dennerlein, Ricarda, Tröder, Simon E, Sprenger, Hans-Georg, Quirós, Pedro M, López-Otín, Carlos, Rugarli, Elena I, Langer, Thomas

“…Proteolytic cleavage of the dynamin-like guanosine triphosphatase OPA1 in mitochondria is emerging as a central regulatory hub that determines mitochondrial…”
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Lesions causing freezing of gait localize to a cerebellar functional network by Fasano, Alfonso, Laganiere, Simon E., Lam, Susy, Fox, Michael D.

“…Objective Freezing of gait is a disabling symptom in Parkinson disease and related disorders, but the brain regions involved in symptom generation remain…”
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Shining new light on mammalian diving physiology using wearable near-infrared spectroscopy by McKnight, J Chris, Bennett, Kimberley A, Bronkhorst, Mathijs, Russell, Debbie J F, Balfour, Steve, Milne, Ryan, Bivins, Matt, Moss, Simon E W, Colier, Willy, Hall, Ailsa J, Thompson, Dave

“…Investigation of marine mammal dive-by-dive blood distribution and oxygenation has been limited by a lack of noninvasive technology for use in freely diving…”
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Speech and Language: Translating the Genome by Deriziotis, Pelagia, Fisher, Simon E.

“…Investigation of the biological basis of human speech and language is being transformed by developments in molecular technologies, including high-throughput…”
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Autobiographical episodic memory-based training for the treatment of mood, anxiety and stress-related disorders: A systematic review and meta-analysis by Hitchcock, Caitlin, Werner-Seidler, Aliza, Blackwell, Simon E., Dalgleish, Tim

“…We review evidence for training programmes that manipulate autobiographical processing in order to treat mood, anxiety, and stress-related disorders, using the…”
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Mental Imagery: From Basic Research to Clinical Practice by Blackwell, Simon E.

“…Mental imagery has long been used in psychological therapies, but only more recently has research started to illuminate the relevant scientific basis. Research…”
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Changing Trends in Asthma Prevalence Among Children by Akinbami, Lara J, Simon, Alan E, Rossen, Lauren M

“…Childhood asthma prevalence doubled from 1980 to 1995 and then increased more slowly from 2001 to 2010. During this second period, racial disparities…”
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Global plate boundary evolution and kinematics since the late Paleozoic by Matthews, Kara J., Maloney, Kayla T., Zahirovic, Sabin, Williams, Simon E., Seton, Maria, Müller, R. Dietmar

“…Many aspects of deep-time Earth System models, including mantle convection, paleoclimatology, paleobiogeography and the deep Earth carbon cycle, require…”
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Evolution of language: Lessons from the genome by Fisher, Simon E.

“…The post-genomic era is an exciting time for researchers interested in the biology of speech and language. Substantive advances in molecular methodologies have…”
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Ethics, Legality, and Safety for Geneticists by Kolstoe, Simon E

“…Never before have we had the methods to edit or manipulate genes and genomes in the way we can today. This volume has described technologies that, a generation…”
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The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria by König, Tim, Tröder, Simon E., Bakka, Kavya, Korwitz, Anne, Richter-Dennerlein, Ricarda, Lampe, Philipp A., Patron, Maria, Mühlmeister, Mareike, Guerrero-Castillo, Sergio, Brandt, Ulrich, Decker, Thorsten, Lauria, Ines, Paggio, Angela, Rizzuto, Rosario, Rugarli, Elena I., De Stefani, Diego, Langer, Thomas

“…Mutations in subunits of mitochondrial m-AAA proteases in the inner membrane cause neurodegeneration in spinocerebellar ataxia (SCA28) and hereditary spastic…”
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Ocular Surface Disease and Quality of Life in Patients With Glaucoma by Skalicky, Simon E, Goldberg, Ivan, McCluskey, Peter

“…Purpose To investigate the relationship between ocular surface disease and glaucoma-related quality of life (QoL), glaucoma severity, and treatment in patients…”
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Covid-19: public messaging on vaccination must heed warnings from confused face mask messaging by Kolstoe, Simon E

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Operando X-ray photoelectron spectroscopy of solid electrolyte interphase formation and evolution in Li2S-P2S5 solid-state electrolytes by Wood, Kevin N., Steirer, K. Xerxes, Hafner, Simon E., Ban, Chunmei, Santhanagopalan, Shriram, Lee, Se-Hee, Teeter, Glenn

“…Solid-state electrolytes such as Li 2 S-P 2 S 5 compounds are promising materials that could enable Li metal anodes. However, many solid-state electrolytes are…”
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