Search Results - "Simon, Carlos"

Deciphering the effect of reproductive tract microbiota on human reproduction by Moreno, Inmaculada, Simon, Carlos

“…Background The female reproductive tract contains an active microbiome comprising mainly bacteria from the Lactobacillus genus, which is associated with a…”
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The Endometrial Microbiome and Its Impact on Human Conception by Toson, Bruno, Simon, Carlos, Moreno, Inmaculada

“…Changes in the female genital tract microbiome are consistently correlated to gynecological and obstetrical pathologies, and tract dysbiosis can impact…”
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Implantation failure of endometrial origin: it is not pathology, but our failure to synchronize the developing embryo with a receptive endometrium by Valdes, Cecilia T., M.D, Schutt, Amy, M.D., M.S, Simon, Carlos, M.D., Ph.D

“…Repeated implantation failure (RIF) is an intriguing, massive failure of reproductive treatment in otherwise healthy women leading to the introduction of…”
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Aging and the environment affect gamete and embryo potential: can we intervene? by Meldrum, David R., M.D, Casper, Robert F., M.D, Diez-Juan, Antonio, Ph.D, Simon, Carlos, M.D., Ph.D, Domar, Alice D., Ph.D, Frydman, Rene, M.D., Ph.D

“…Optimal maturation of the oocyte depends on its environment and determines embryo competence, because the embryonic genome is not active until the cleavage…”
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A 5-year multicentre randomized controlled trial comparing personalized, frozen and fresh blastocyst transfer in IVF by Simón, Carlos, Gómez, Carlos, Cabanillas, Sergio, Vladimirov, Iavor, Castillón, Gemma, Giles, Juan, Boynukalin, Kubra, Findikli, Necati, Bahçeci, Mustafa, Ortega, Israel, Vidal, Carmina, Funabiki, Miyako, Izquierdo, Alexandra, López, Lourdes, Portela, Susana, Frantz, Nilo, Kulmann, Marcos, Taguchi, Sagiri, Labarta, Elena, Colucci, Francisco, Mackens, Shari, Santamaría, Xavier, Muñoz, Elkin, Barrera, Saúl, García-Velasco, Juan Antonio, Fernández, Manuel, Ferrando, Marcos, Ruiz, María, Mol, Ben W, Valbuena, Diana

“…Does clinical performance of personalized embryo transfer (PET) guided by endometrial receptivity analysis (ERA) differ from frozen embryo transfer (FET) or…”
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Meta-signature of human endometrial receptivity: a meta-analysis and validation study of transcriptomic biomarkers by Altmäe, Signe, Koel, Mariann, Võsa, Urmo, Adler, Priit, Suhorutšenko, Marina, Laisk-Podar, Triin, Kukushkina, Viktorija, Saare, Merli, Velthut-Meikas, Agne, Krjutškov, Kaarel, Aghajanova, Lusine, Lalitkumar, Parameswaran G., Gemzell-Danielsson, Kristina, Giudice, Linda, Simón, Carlos, Salumets, Andres

“…Previous transcriptome studies of the human endometrium have revealed hundreds of simultaneously up- and down-regulated genes that are involved in endometrial…”
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Evidence that the endometrial microbiota has an effect on implantation success or failure by Moreno, Inmaculada, PhD, Codoñer, Francisco M., PhD, Vilella, Felipe, PhD, Valbuena, Diana, MD, PhD, Martinez-Blanch, Juan F., PhD, Jimenez-Almazán, Jorge, PhD, Alonso, Roberto, Alamá, Pilar, MD, PhD, Remohí, Jose, MD, PhD, Pellicer, Antonio, MD, PhD, Ramon, Daniel, PhD, Simon, Carlos, MD, PhD

“…Background Bacterial cells in the human body account for 1–3% of total body weight and are at least equal in number to human cells. Recent research has focused…”
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The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology by Moreno, Inmaculada, Cicinelli, Ettore, Garcia-Grau, Iolanda, Gonzalez-Monfort, Marta, Bau, Davide, Vilella, Felipe, De Ziegler, Dominique, Resta, Leonardo, Valbuena, Diana, Simon, Carlos

“…Chronic endometritis is a persistent inflammation of the endometrial mucosa caused by bacterial pathogens such as Enterobacteriaceae, Enterococcus,…”
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Why should patients experience infertility or poor outcomes before using assisted reproductive technologies? by Simon, Carlos, M.D., Ph.D

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Incidence, Origin, and Predictive Model for the Detection and Clinical Management of Segmental Aneuploidies in Human Embryos by Girardi, Laura, Serdarogullari, Munevver, Patassini, Cristina, Poli, Maurizio, Fabiani, Marco, Caroselli, Silvia, Coban, Onder, Findikli, Necati, Boynukalin, Fazilet Kubra, Bahceci, Mustafa, Chopra, Rupali, Canipari, Rita, Cimadomo, Danilo, Rienzi, Laura, Ubaldi, Filippo, Hoffmann, Eva, Rubio, Carmen, Simon, Carlos, Capalbo, Antonio

“…Despite next-generation sequencing, which now allows for the accurate detection of segmental aneuploidies from in vitro fertilization embryo biopsies, the…”
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Avoid mixing apples and oranges: blastocysts diagnosed with uniform whole chromosome aneuploidies are reproductively incompetent and their transfer is harmful by Capalbo, Antonio, Cimadomo, Danilo, Rienzi, Laura, Garcìa-Velasco, Juan Antonio, Simòn, Carlos, Ubaldi, Filippo Maria

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Human pre-implantation embryo development by Niakan, Kathy K, Han, Jinnuo, Pedersen, Roger A, Simon, Carlos, Pera, Renee A Reijo

“…Understanding human pre-implantation development has important implications for assisted reproductive technology (ART) and for human embryonic stem cell…”
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Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis by Vera-Rodriguez, Maria, Chavez, Shawn L., Rubio, Carmen, Pera, Renee A. Reijo, Simon, Carlos

“…Aneuploidies are prevalent in the human embryo and impair proper development, leading to cell cycle arrest. Recent advances in imaging and molecular and…”
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Optimizing clinical exome design and parallel gene-testing for recessive genetic conditions in preconception carrier screening: Translational research genomic data from 14,125 exomes by Capalbo, Antonio, Valero, Roberto Alonso, Jimenez-Almazan, Jorge, Pardo, Pere Mir, Fabiani, Marco, Jiménez, David, Simon, Carlos, Rodriguez, Julio Martin

“…Limited translational genomic research data have been reported on the application of exome sequencing and parallel gene testing for preconception carrier…”
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Endometrial microbiota composition is associated with reproductive outcome in infertile patients by Moreno, Inmaculada, Garcia-Grau, Iolanda, Perez-Villaroya, David, Gonzalez-Monfort, Marta, Bahçeci, Mustafa, Barrionuevo, Marcelo J, Taguchi, Sagiri, Puente, Elena, Dimattina, Michael, Lim, Mei Wei, Meneghini, Georgina, Aubuchon, Mira, Leondires, Mark, Izquierdo, Alexandra, Perez-Olgiati, Martina, Chavez, Alejandro, Seethram, Ken, Bau, Davide, Gomez, Carlos, Valbuena, Diana, Vilella, Felipe, Simon, Carlos

“…Previous evidence indicates associations between the female reproductive tract microbiome composition and reproductive outcome in infertile patients undergoing…”
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Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions by Medrano, Jose V., Ph.D, Rombaut, Charlotte, M.Sc, Simon, Carlos, M.D, Pellicer, Antonio, M.D, Goossens, Ellen, Ph.D

“…Objective To study the ability of human spermatogonial stem cells (hSSCs) to proliferate in vitro under mouse spermatogonial stem cell (mSSC) culture…”
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The role of ZFP57 and additional KRAB-zinc finger proteins in the maintenance of human imprinted methylation and multi-locus imprinting disturbances by Monteagudo-Sánchez, Ana, Hernandez Mora, Jose Ramon, Simon, Carlos, Burton, Adam, Tenorio, Jair, Lapunzina, Pablo, Clark, Stephen, Esteller, Manel, Kelsey, Gavin, López-Siguero, Juan Pedro, de Nanclares, Guiomar Perez, Torres-Padilla, Maria-Elena, Monk, David

“…Abstract Genomic imprinting is an epigenetic process regulated by germline-derived DNA methylation that is resistant to embryonic reprogramming, resulting in…”
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Endometrial Receptivity Analysis (ERA): data versus opinions by Ruiz-Alonso, Maria, Valbuena, Diana, Gomez, Carlos, Cuzzi, Juliana, Simon, Carlos

“…Abstract This article summarises and contextualises the accumulated basic and clinical data on the ERA test and addresses specific comments and opinions…”
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Does an increased body mass index affect endometrial gene expression patterns in infertile patients? A functional genomics analysis by Comstock, Ioanna A., M.D, Diaz-Gimeno, Patricia, Ph.D, Cabanillas, Sergio, M.D, Bellver, Jose, M.D, Sebastian-Leon, Patricia, Ph.D, Shah, Meera, M.D, Schutt, Amy, M.D, Valdes, Cecilia T., M.D, Ruiz-Alonso, Maria, M.Sc, Valbuena, Diana, M.D., Ph.D, Simon, Carlos, M.D., Ph.D, Lathi, Ruth B., M.D

“…Objective To analyze the transcriptomic profile of endometrial gene alterations during the window of implantation in infertile obese patients. Design…”
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Effect of aging on the human myometrium at single-cell resolution by Punzon-Jimenez, Paula, Machado-Lopez, Alba, Perez-Moraga, Raul, Llera-Oyola, Jaime, Grases, Daniela, Galvez-Viedma, Marta, Sibai, Mustafa, Satorres-Perez, Elena, Lopez-Agullo, Susana, Badenes, Rafael, Ferrer-Gomez, Carolina, Porta-Pardo, Eduard, Roson, Beatriz, Simon, Carlos, Mas, Aymara

“…Age-associated myometrial dysfunction can prompt complications during pregnancy and labor, which is one of the factors contributing to the 7.8-fold increase in…”
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