Search Results - "Simmons, Kirk"

Further supporting evidence for the SATB2-associated syndrome found through whole exome sequencing by Zarate, Yuri A., Perry, Hazel, Ben-Omran, Tawfeg, Sellars, Elizabeth A., Stein, Quinn, Almureikhi, Mariam, Simmons, Kirk, Klein, Ophir, Fish, Jennifer, Feingold, Murray, Douglas, Jessica, Kruer, Michael C., Si, Yue, Mao, Rong, McKnight, Dianalee, Gibellini, Federica, Retterer, Kyle, Slavotinek, Anne

“…The SATB2‐associated syndrome (SAS) was recently proposed as a clinically recognizable syndrome that results from deleterious alterations of the SATB2 gene in…”
Get full text

P369: SATB2-associated syndrome severity score: Genotype/phenotype correlations and the SATB2 portal by Zarate, Yuri, Bosanko, Katherine, Kannan, Amrit, Thomason, Ashlen, Nutt, Beth, Kumar, Nihit, Simmons, Kirk, Hiegert, Aaron, Hartzell, Larry, Johnson, Adam, Prater, Tabitha, Kimberlain, Jillian, Caffrey, Aisling, Stefanski, Arthur, Brünger, Tobias, Pérez-Palma, Eduardo, Lal, Dennis

Get full text

A Simple Structure-Based Calculator for Estimating Vapor Pressure by Simmons, Kirk A

“…The development of an estimator for vapor pressure based upon organic functional groups is described. This vapor pressure calculator permits prediction of…”
Get full text

Improved chiral derivatizing agents for the chromatographic resolution of racemic primary amines by Pirkle, William H, Simmons, Kirk A

Get full text

Comparative Study of Machine-Learning and Chemometric Tools for Analysis of In-Vivo High-Throughput Screening Data by Simmons, Kirk, Kinney, John, Owens, Aaron, Kleier, Dan, Bloch, Karen, Argentar, Dave, Walsh, Alicia, Vaidyanathan, Ganesh

“…High-throughput screening (HTS) has become a central tool of many pharmaceutical and crop-protection discovery operations. If HTS screening is carried out at…”
Get full text

Practical Outcomes of Applying Ensemble Machine Learning Classifiers to High-Throughput Screening (HTS) Data Analysis and Screening by Simmons, Kirk, Kinney, John, Owens, Aaron, Kleier, Daniel A, Bloch, Karen, Argentar, Dave, Walsh, Alicia, Vaidyanathan, Ganesh

“…Over the years numerous papers have presented the effectiveness of various machine learning methods in analyzing drug discovery biological screening data. The…”
Get full text

Predicting the activity of soil-applied insecticides from their physicochemical properties by Simmons, Kirk A, Lew, Albert C, Silverman, I. Robert, Ali, Syed F

“…The influence of physicochemical properties on the activity of soil-applied insecticides is discussed. Physical property-based rules are developed which allow…”
Get full text

Synthesis and activity optimization of herbicidal substituted 4-aryl-1,2,4-triazole-5(1H)-thiones by Simmons, Kirk A, Dixson, John A, Halling, Blaik P, Plummer, Ernest L, Plummer, Marjorie J, Tymonko, John M, Schmidt, Robert J, Wyle, Mike J, Webster, Charles A, et al, .

“…The process of sorting leads identified via screening can be made more efficient by the application of experimental design strategies. Such strategies were…”
Get full text

Nuclear magnetic resonance determination of enantiomeric composition and absolute configuration of amines, alcohols, and thiols with .alpha.-[1-(9-anthryl)-2,2,2-trifluoroethoxy]acetic acid as a chiral derivatizing agent by Pirkle, William H, Simmons, Kirk A

Get full text

Developing physical property-based rules which govern the greenhouse activity of herbicidal 4-aryl-1,2,4-triazole-5(1H)-thiones by Simmons, Kirk A, Dixson, John A, Halling, Blaik P, Plummer, Ernest L, Plummer, Marjorie J, Tymonko, John M, Schmidt, Robert J, Wyle, Mike J, Webster, Charles A, et al, .

Get full text

Dynamic NMR studies of diastereomeric carbamates: implications toward the determination of relative configuration by NMR by Pirkle, W. H, Simmons, Kirk A, Boeder, Charles W

Get full text

Synthesis and biological evaluation of destruxin A and related analogs by Ast, T., Schmidt, M., Germeroth, L., Wenschuh, H., Barron, E., Kinne, L., Simmons, K.

“…: This report describes the development of an efficient solid‐phase synthesis protocol and adaptation of reported solution phase procedures for the synthesis…”
Get full text

SYNTHESIS AND NUCLEAR MAGNETIC RESONANCE STUDIES OF SELECTED DIASTEREOMERIC COMPOUNDS by SIMMONS, KIRK ALLEN

“…The coordination site of tris(1,1,1,2,2,3,3-heptafluoro-7,7-dimethyloctane-4,6-dionato)ytterbium (III) has been determined in oxaziridines. Comparison of the…”
Get full text