Search Results - "Simmons, Christine E"
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Current Challenges and Disparities in the Delivery of Equitable Breast Cancer Care in Canada
Published in Current oncology (Toronto) (01-08-2023)“…Recent exciting advances in the diagnosis and management of breast cancer have improved outcomes for Canadians diagnosed and living with breast cancer…”
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Canadian Consensus for Biomarker Testing and Treatment of TRK Fusion Cancer in Adults
Published in Current oncology (Toronto) (15-01-2021)“…The tyrosine receptor kinase (TRK) inhibitors larotrectinib and entrectinib were recently approved in Canada for the treatment of solid tumours harbouring…”
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3
Positive progress: current and evolving role of immune checkpoint inhibitors in metastatic triple-negative breast cancer
Published in Therapeutic Advances in Medical Oncology (2020)“…Background: Triple-negative breast cancer (TNBC) represents an aggressive breast cancer subtype with historically poor overall outcomes, due primarily to a…”
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4
Overcoming Inertia to Tame the Red Devil
Published in JACC CardioOncology (01-09-2019)“…[Display omitted]…”
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Treatment differences and long-term outcomes in adults and children with Ewing sarcoma
Published in Cancer epidemiology (01-10-2024)“…Ewing sarcoma is an aggressive malignancy primarily affecting children and adolescents. Limited research is available on treatment practices, clinical course,…”
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A phase 2 trial exploring the effects of high‐dose (10,000 IU/day) vitamin D3 in breast cancer patients with bone metastases
Published in Cancer (15-01-2010)“…BACKGROUND: Vitamin D deficiency has potential roles in breast cancer etiology and progression. Vitamin D deficiency has also been associated with increased…”
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7
Is knowledge translation adequate? A quality assurance study of staging investigations in early stage breast cancer patients
Published in Breast cancer research and treatment (01-02-2012)“…After primary surgery, patients diagnosed with early stage breast cancer undergo radiological investigations based on pathologic stage of disease to rule out…”
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Comparison of treatment effect and long-term outcomes for pediatric and adult Ewing sarcoma patients in British Columbia, Canada
Published in Journal of clinical oncology (20-05-2021)“…Abstract only 11531 Background: Treatment of Ewing Sarcoma (EWS) is challenging. While it is known to be sensitive to chemotherapy and radiation, the number of…”
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Real world evidence for continuing HER2-directed therapy for metastatic breast cancer
Published in Journal of clinical oncology (01-06-2023)“…e18623 Background: Continuing HER2-directed therapy in metastatic breast cancer (MBC) beyond first line has been demonstrated to improve progression free…”
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10
Variations in Ewing sarcoma and rhabdomyosarcoma patient outcomes based on treatment center volume
Published in Journal of clinical oncology (01-06-2022)“…e18530 Background: Due to their rarity and requirement for multi-modality care, evidence suggests (and guidelines recommend) patients (pts) with Ewing Sarcoma…”
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Impact of sequence order of anthracyclines and taxanes in neoadjuvant chemotherapy for breast cancer: Results from a prospective institutional database
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e12619 Background: There has been growing interest in the optimal sequencing of anthracyclines and taxanes in neoadjuvant chemotherapy (NACT) for…”
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Application of neo-bioscore to a real-world cohort: Potential implications for patient selection, for escalation, and de-escalation of therapy
Published in Journal of clinical oncology (20-05-2020)“…Abstract only e19094 Background: Recent studies have demonstrated that escalation of therapy for patients with residual disease after neoadjuvant therapy for…”
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The impact of mild left ventricular dysfunction on trastuzumab use and oncologic outcomes in early stage breast cancer therapy
Published in Journal of clinical oncology (20-05-2017)“…Abstract only e18148 Background: Trastuzumab (T) significantly reduces the risk of breast cancer recurrence, but may be associated with an increased incidence…”
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Examining social media peer support and improving psychosocial outcomes for young women with breast cancer
Published in Journal of clinical oncology (01-10-2021)“…Abstract only 162 Background: Young women with breast cancer (YWBC) have unique survivorship needs due to life stage at point of diagnosis. Peer support sought…”
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Impact of Oncotype-DX testing on choice of chemotherapy
Published in Journal of clinical oncology (20-05-2017)“…Abstract only e12049 Background: The Oncotype DX test has been shown to change treatment plans in ~30% of cases, but it is unclear if it changes the type of…”
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Comparing outcomes of neoadjuvant endocrine therapy versus chemotherapy in ER-positive breast cancer: Results from a prospective institutional database
Published in Journal of clinical oncology (20-05-2017)“…Abstract only 581 Background: While neoadjuvant chemotherapy (NACT) has been established as the standard of care for medically fit patients, there has been…”
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Comparative efficacy of neoadjuvant to adjuvant chemotherapy for the treatment of early-stage HER2 negative breast cancer: A population-based analysis
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e12100 Background: The use of neoadjuvant treatment has increased over the past decade due to its ability to assess tumour sensitivity to…”
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An assessment of neoadjuvant therapy for breast cancer and treatment wait times at the BC Cancer Agency Vancouver
Published in Journal of clinical oncology (20-10-2014)“…Abstract only 140 Background: Neoadjuvant therapy (NAT) is widely considered to be the standard of care for patients diagnosed with locally advanced breast…”
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Needle-to-needle time: Does prompt initiation of treatment post biopsy improve pCR in neoadjuvant chemotherapy (NAC) for breast cancer?
Published in Journal of clinical oncology (20-05-2016)“…Abstract only…”
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Preoperative triage and multidisciplinary consultation for patients with breast cancer: A pilot study between surgery and medical oncology
Published in Journal of clinical oncology (01-03-2016)“…Abstract only 208 Background: Breast cancer management has become exceedingly collaborative across specialties. Preoperative multidisciplinary input in…”
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