Search Results - "Simeón, Pilar"

Effect of bosentan in pulmonary hypertension development in systemic sclerosis patients with digital ulcers by Castellví, Ivan, Simeón, Carmen Pilar, Sarmiento, Monica, Casademont, Jordi, Corominas, Hèctor, Fonollosa, Vicenç

“…Systemic sclerosis is a disease where microcirculation damage is critical in their beginning and vascular complications have similar pathogenic findings…”
Get full text

High sensitivity and negative predictive value of the DETECT algorithm for an early diagnosis of pulmonary arterial hypertension in systemic sclerosis: application in a single center by Guillén-Del Castillo, Alfredo, Callejas-Moraga, Eduardo L, García, Gabriela, Rodríguez-Palomares, José F, Román, Antonio, Berastegui, Cristina, López-Meseguer, Manuel, Domingo, Enric, Fonollosa-Plá, Vicente, Simeón-Aznar, Carmen Pilar

“…Pulmonary arterial hypertension (PAH) is one of the most relevant causes of death in systemic sclerosis. The aims of this study were to analyse the recently…”
Get full text

Epigenomics and transcriptomics of systemic sclerosis CD4+ T cells reveal long-range dysregulation of key inflammatory pathways mediated by disease-associated susceptibility loci by Li, Tianlu, Ortiz-Fernández, Lourdes, Andrés-León, Eduardo, Ciudad, Laura, Javierre, Biola M., López-Isac, Elena, Guillén-Del-Castillo, Alfredo, Simeón-Aznar, Carmen Pilar, Ballestar, Esteban, Martin, Javier

“…Background Systemic sclerosis (SSc) is a genetically complex autoimmune disease mediated by the interplay between genetic and epigenetic factors in a multitude…”
Get full text

Good outcome of interstitial lung disease in patients with scleroderma associated to anti-PM/Scl antibody by Guillen-Del Castillo, Alfredo, MD, Pilar Simeón-Aznar, Carmen, MD, PhD, Fonollosa-Pla, Vicent, MD, PhD, Alonso-Vila, Serafín, MD, Reverte-Vinaixa, María M., MD, Muñoz, Xavier, MD, PhD, Pallisa, Esther, MD, Selva-O׳Callaghan, Albert, MD, PhD, Fernández-Codina, Andreu, MD, Vilardell-Tarrés, Miquel, MD, PhD

“…Abstract Objective The objective of this article was to establish the clinical course of interstitial lung disease (ILD) in scleroderma related to the presence…”
Get full text

Cardiac tamponade and severe pericardial effusion in systemic sclerosis: report of nine patients and review of the literature by Fernández Morales, Alejandro, Iniesta, Nerea, Fernández‐Codina, Andreu, Vaz de Cunha, Joana, Pérez Romero, Teresa, Hurtado García, Robert, Simeón‐Aznar, Carmen Pilar, Fonollosa, Vicent, Cervera, Ricard, Espinosa, Gerard

“…Aim To describe the clinical characteristics, treatment and outcome of patients with systemic sclerosis (SSc) developing severe pericardial effusion or cardiac…”
Get full text

Early- versus Late-Onset Systemic Sclerosis: Differences in Clinical Presentation and Outcome in 1037 Patients by Alba, Marco A., Velasco, César, Simeón, Carmen Pilar, Fonollosa, Vicent, Trapiella, Luis, Egurbide, María Victoria, Sáez, Luis, Castillo, María Jesús, Callejas, José Luis, Camps, María Teresa, Tolosa, Carles, Ríos, Juan José, Freire, Mayka, Vargas, José Antonio, Espinosa, Gerard

“…Peak age at onset of systemic sclerosis (SSc) is between 20 and 50 years, although SSc is also described in both young and elderly patients. We conducted the…”
Get full text

COVID GEAS: COVID-19 National Survey in Patients With Systemic Autoimmune Diseases by Gracia, Borja Del Carmelo, Sáez, Luis, Pallarés, Lucio, Velilla, Jose, Marín, Adela, Martinez-Lostao, Luis, Simeón, Carmen Pilar, Fanlo, Patricia

“…COVID-19 outcomes in population with systemic autoimmune diseases (SAD) remain poorly understood. The aim was to examine demographic and clinical factors…”
Get full text

Anti-U11/U12 Antibodies as a Rare but Important Biomarker in Patients with Systemic Sclerosis: A Narrative Review by Fritzler, Marvin J, Bentow, Chelsea, Beretta, Lorenzo, Palterer, Boaz, Perurena-Prieto, Janire, Sanz-Martínez, Maria Teresa, Guillen-Del-Castillo, Alfredo, Marín, Ana, Fonollosa-Pla, Vicent, Callejas-Moraga, Eduardo, Simeón-Aznar, Carmen Pilar, Mahler, Michael

“…Anti-nuclear (ANA) are present in approximately 90% of systemic sclerosis (SSc) patients and are key biomarkers in supporting the diagnosis and determining the…”
Get full text

Mortality and survival in systemic sclerosis: Systematic review and meta-analysis by Rubio-Rivas, Manuel, MD, Royo, Cristina, MD, Simeón, Carmen Pilar, MD, PhD, Corbella, Xavier, MD, PhD, Fonollosa, Vicent, MD, PhD

“…Abstract Objective To determine the mortality, survival, and causes of death in patients with systemic sclerosis (SSc) through a meta-analysis of the…”
Get full text

The role of TAPSE/sPAP ratio in predicting pulmonary hypertension and mortality in the systemic sclerosis EUSTAR cohort by Colalillo, Amalia, Hoffmann-Vold, Anna-Maria, Pellicano, Chiara, Romaniello, Antonella, Gabrielli, Armando, Hachulla, Eric, Smith, Vanessa, Simeón-Aznar, Carmen-Pilar, Castellví, Ivan, Airò, Paolo, Truchetet, Marie-Elise, Siegert, Elise, Distler, Oliver, Rosato, Edoardo

“…The study aim was to evaluate the predictive role of the echocardiography-derived tricuspid annular plane systolic excursion/systolic pulmonary artery pressure…”
Get full text

Health‐Related Internet Use by Patients With Systemic Sclerosis and Other Autoimmune Diseases: Comment on the Article by van der Vaart et al by Ortego‐Centeno, Norberto, Callejas‐Rubio, José‐Luis, Ríos‐Fernández, Raquel, Simeón‐Aznar, Carmen‐Pilar

Get full text

Autoantibodies to stratify systemic sclerosis patients into clinically actionable subsets by Mahler, Michael, Hudson, Marie, Bentow, Chelsea, Roup, Fabrece, Beretta, Lorenzo, Pilar Simeón, Carmen, Guillén-Del-Castillo, Alfredo, Casas, Sílvia, Fritzler, Marvin J.

“…Systemic sclerosis (SSc) is a rare chronic disease of unknown etiology characterized by vascular abnormalities and fibrosis involving the skin and internal…”
Get full text

Standardized incidence ratios and risk factors for cancer in patients with systemic sclerosis: Data from the Spanish Scleroderma Registry (RESCLE) by Carbonell, Cristina, Marcos, Miguel, Guillén-del-Castillo, Alfredo, Rubio-Rivas, Manuel, Argibay, Ana, Marín-Ballvé, Adela, Rodríguez-Pintó, Ignasi, Baldà-Masmiquel, Maria, Callejas-Moraga, Eduardo, Colunga, Dolores, Sáez-Comet, Luis, González-Echávarri, Cristina, Ortego-Centeno, Norberto, Marí-Alfonso, Begoña, Vargas-Hitos, José-Antonio, Todolí-Parra, José-Antonio, Trapiella, Luis, Herranz-Marín, María-Teresa, Freire, Mayka, Castro-Salomó, Antoni, Perales-Fraile, Isabel, Madroñero-Vuelta, Ana-Belén, Sánchez-García, María-Esther, Ruiz-Muñoz, Manuel, González-García, Andrés, Sánchez-Redondo, Jorge, de-la-Red-Bellvis, Gloria, Fernández-Luque, Alejandra, Muela-Molinero, Alberto, Lledó, Gema-María, Tolosa-Vilella, Carles, Fonollosa-Pla, Vicent, Chamorro, Antonio-Javier, Simeón-Aznar, Carmen-Pilar

“…Patients with systemic sclerosis (SSc) are at increased risk of cancer, a growing cause of non–SSc-related death among these patients. We analyzed the…”
Get full text

Longterm Efficacy and Safety of Monotherapy versus Combination Therapy in Systemic Sclerosis-associated Pulmonary Arterial Hypertension: A Retrospective RESCLE Registry Study by Pestaña-Fernández, Melani, Rubio-Rivas, Manuel, Tolosa-Vilella, Carles, Guillén-Del-Castillo, Alfredo, Freire, Mayka, Vargas-Hitos, Jose Antonio, Todolí-Parra, Jose Antonio, Rodríguez-Carballeira, Mónica, Marín-Ballvé, Adela, Espinosa, Gerard, Colunga-Argüelles, Dolores, Ortego-Centeno, Norberto, Trapiella-Martínez, Luis, Carbonell-Muñoz, Cristina, Pla-Salas, Xavier, Perales-Fraile, Isabel, Corbella, Xavier, Fonollosa-Pla, Vicent, Simeón-Aznar, Carmen Pilar

“…Monotherapy is an option as first-line therapy for pulmonary arterial hypertension (PAH). However, combination therapy is a beneficial alternative. Our…”
Get full text

The incidence rate of pulmonary arterial hypertension and scleroderma renal crisis in systemic sclerosis patients with digital ulcers on endothelin antagonist receptors (ERAs) and phosphodiesterase-5 inhibitors (PDE5i) by Pestaña-Fernández, Melani, Rubio-Rivas, Manuel, Tolosa-Vilella, Carles, Guillén-Del-Castillo, Alfredo, Colunga-Argüelles, Dolores, Argibay, Ana, Marí-Alfonso, Begoña, Marín-Ballvé, Adela, Pla-Salas, Xavier, Chamorro, Antonio-J, Castro-Salomó, Antoni, Madroñero-Vuelta, Ana Belén, Sánchez-García, María Esther, Sáez-Comet, Luis, González-Echávarri, Cristina, Ortego-Centeno, Norberto, Vargas-Hitos, José Antonio, Todolí-Parra, José Antonio, Trapiella-Martínez, Luis, Lledó, Gema María, Freire, Mayka, Fonollosa-Pla, Vicent, Simeón-Aznar, Carmen Pilar

“…Endothelin antagonist receptors (ERAs) and phosphodiesterase-5 inhibitors (PDE5i) are beneficial in pulmonary arterial hypertension (PAH) and digital ulcers…”
Get full text

Quantitative videocapillaroscopy correlates with functional respiratory parameters: a clue for vasculopathy as a pathogenic mechanism for lung injury in systemic sclerosis by Guillén-Del-Castillo, Alfredo, Simeón-Aznar, Carmen Pilar, Callejas-Moraga, Eduardo L, Tolosa-Vilella, Carles, Alonso-Vila, Serafín, Fonollosa-Pla, Vicente, Selva-O'Callaghan, Albert

“…To determine whether lung involvement is related to microvascular perturbations, nailfold videocapillaroscopy (NVC) was performed in patients with systemic…”
Get full text

Association of TNFSF4 (OX40L) polymorphisms with systemic sclerosis–related calcinosis by Duffus, Kate, López-Isac, Elena, Teruel, Maria, Simeón, Carmen Pilar, Carreria, Patricia, Ortego-Centeno, Norberto, Vicente, Esther, Worthington, Jane, Herrick, Ariane L, Martin, Javier

Get full text

Registry of the Spanish Network for Systemic Sclerosis: Clinical Pattern According to Cutaneous Subsets and Immunological Status by Simeón-Aznar, Carmen Pilar, MD, PhD, Fonollosa-Plá, Vicent, MD, PhD, Tolosa-Vilella, Carles, MD, PhD, Espinosa-Garriga, Gerard, MD, PhD, Ramos-Casals, Manel, MD, PhD, Campillo-Grau, Mercedes, PhD, García-Hernández, Francisco José, MD, PhD, Castillo-Palma, María Jesús, MD, PhD, Sánchez-Román, Julio, MD, PhD, Callejas-Rubio, José Luis, MD, PhD, Ortego-Centeno, Norberto, MD, PhD, Egurbide-Arberas, Maria Victoria, MD, PhD, Trapiellla-Martínez, Luis, MD, Gallego-Villalobos, María, MD, Sáez-Comet, Luis, MD, PhD, Velilla-Marco, José, MD, PhD, Camps-García, María Teresa, MD, de Ramón-Garrido, Enrique, MD, PhD, Esteban Marcos, Eva María, MD, Pallarés-Ferreres, Lucio, MD, PhD, Hidalgo-Tenorio, Carmen, MD, PhD, Sabio-Sánchez, José Mario, MD, PhD, Gómez-de la Torre, Ricardo, MD, PhD, Salvador-Cervello, Gonzalo, MD, Rios-Blanco, Juan José, MD, PhD, Gil-Aguado, Antonio, MD, Vilardell-Tarrés, Miquel, MD, PhD

“…Objective To investigate the incidence of clinical and immunological characteristics of a large cohort of Spanish patients with scleroderma (SSc) and…”
Get full text

Right Ventricular Dysfunction Assessed Through Cardiac Resonance as a Prognostic Predictor in Systemic Sclerosis by Fernandez, Jorge Rodrigo, Illuminato, Federica, Castillo, Alfredo Guillen Del, Valente, Filipa, Eyras, Lucia Rodriguez, Aznar, Carmen Pilar Simeon, Calabria, Hug Cuellar, Roque, Albert, Palomares, José F Rodríguez

Get full text

Treatment of Raynaud's phenomenon by Fonollosa-Pla, V, Pilar Simeón-Aznar, C, Vilardell-Tarrés, M

“…Raynaud's phenomenon (RP) is a clinical picture characterized by the presence of recurrent episodes of vasospasm that is precipitated by cold or other stimuli…”
Get more information