Search Results - "Simas, J Pedro"

Endemic SARS-CoV-2 will maintain post-pandemic immunity by Veldhoen, Marc, Simas, J Pedro

“…Copyright © 2021, Springer Nature Limited COVID-19 vaccinations have started. They will stop the pandemic. Citing recent data that are in line with…”
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Seroprevalence of anti‐SARS‐CoV‐2 antibodies in COVID‐19 patients and healthy volunteers up to 6 months post disease onset by Figueiredo-Campos, Patricia, Blankenhaus, Birte, Mota da Silva, Maria Catarina, Gomes, Andreia, Serrano, Marta, Ariotti, Silvia, Costa, Catarina, Nunes Cabaço, Helena Isabel Marques, M. Mendes, António, Gaspar, Pedro, Pereira‐Santos, M. Conceição, Rodrigues, Fabiana, Condeço, Jorge, Escoval, M. Antonia, Santos, Matilde, Ramos de Almeida Ramirez, Mário Nuno, Melo Cristino, José, Simas, J Pedro, Vasconcelos, Eugenia, Afonso, Ângela, Veldhoen, Marc

“…© 2020 The Authors. European Journal of Immunology published by Wiley‐VCH GmbH. This is an open access article under the terms of the Creative Commons…”
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IgG antibodies to SARS-CoV-2 in asymptomatic blood donors at two time points in Karachi by Hasan, Muhammad, Moiz, Bushra, Qaiser, Shama, Masood, Kiran Iqbal, Ghous, Zara, Hussain, Areeba, Ali, Natasha, Simas, J. Pedro, Veldhoen, Marc, Alves, Paula, Abidi, Syed Hani, Ghias, Kulsoom, Khan, Erum, Hasan, Zahra

“…Introduction An estimated 1.5 million cases were reported in Pakistan until 23 March, 2022. However, SARS-CoV-2 PCR testing capacity has been limited and the…”
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De Novo Human Angiotensin-Converting Enzyme 2 Decoy NL-CVX1 Protects Mice From Severe Disease After Severe Acute Respiratory Syndrome Coronavirus 2 Infection by Rebelo, Maria, Tang, Cong, Coelho, Ana R, Labão-Almeida, Carlos, Schneider, Matthias M, Tatalick, Laurie, Ruivo, Pedro, de Miranda, Marta Pires, Gomes, Andreia, Carvalho, Tânia, Walker, Matthew J, Ausserwoeger, Hannes, Pedro Simas, J, Veldhoen, Marc, Knowles, Tuomas P J, Silva, Daniel-Adriano, Shoultz, David, Bernardes, Gonçalo J L

“…Abstract The emergence of novel variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) underscores the need to investigate alternative…”
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Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis by Figueiredo, Nuno, Chora, Angelo, Raquel, Helena, Pejanovic, Nadja, Pereira, Pedro, Hartleben, Björn, Neves-Costa, Ana, Moita, Catarina, Pedroso, Dora, Pinto, Andreia, Marques, Sofia, Faridi, Hafeez, Costa, Paulo, Gozzelino, Raffaella, Zhao, Jimmy L., Soares, Miguel P., Gama-Carvalho, Margarida, Martinez, Jennifer, Zhang, Qingshuo, Döring, Gerd, Grompe, Markus, Simas, J. Pedro, Huber, Tobias B., Baltimore, David, Gupta, Vineet, Green, Douglas R., Ferreira, João A., Moita, Luis F.

“…Severe sepsis remains a poorly understood systemic inflammatory condition with high mortality rates and limited therapeutic options in addition to organ…”
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A rapid real-time polymerase chain reaction-based live virus microneutralization assay for detection of neutralizing antibodies against SARS-CoV-2 in blood/serum by Abidi, Syed Hani, Imtiaz, Kehkashan, Kanji, Akbar, Qaiser, Shama, Khan, Erum, Iqbal, Kiran, Veldhoen, Marc, Ghias, Kulsoom, Simas, J Pedro, Hasan, Zahra

“…Copyright: © 2021 Abidi et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits…”
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Maternal retinoids control type 3 innate lymphoid cells and set the offspring immunity by van de Pavert, Serge A., Ferreira, Manuela, Domingues, Rita G., Ribeiro, Hélder, Molenaar, Rosalie, Moreira-Santos, Lara, Almeida, Francisca F., Ibiza, Sales, Barbosa, Inês, Goverse, Gera, Labão-Almeida, Carlos, Godinho-Silva, Cristina, Konijn, Tanja, Schooneman, Dennis, O’Toole, Tom, Mizee, Mark R., Habani, Yasmin, Haak, Esther, Santori, Fabio R., Littman, Dan R., Schulte-Merker, Stefan, Dzierzak, Elaine, Simas, J. Pedro, Mebius, Reina E., Veiga-Fernandes, Henrique

“…Dietary vitamin A during pregnancy is required for the formation of secondary lymphoid organs of the developing embryo and affects the offspring’s immune…”
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MLL1 is regulated by KSHV LANA and is important for virus latency by Tan, Min, Li, Shijun, Juillard, Franceline, Chitas, Rute, Custódio, Tânia F, Xue, Han, Szymula, Agnieszka, Sun, Qiming, Liu, Bing, Álvarez, Ángel L, Chen, She, Huang, Jing, Simas, J Pedro, McVey, Colin E, Kaye, Kenneth M

“…Abstract Mixed lineage leukemia 1 (MLL1) is a histone methyltransferase. Kaposi's sarcoma-associated herpesvirus (KSHV) is a leading cause of malignancy in…”
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Kaposi's sarcoma herpesvirus latency-associated nuclear antigen broadly regulates viral gene expression and is essential for lytic infection by Li, Shijun, Wang, Mengbo, Van Sciver, Nicholas, Szymula, Agnieszka, Tumuluri, Vinayak Sadasivam, George, Athira, Ramachandran, Akshaya, Raina, Komal, Costa, Catarina N, Zhao, Bo, Kazemian, Majid, Simas, J Pedro, Kaye, Kenneth M

“…Kaposi's sarcoma herpesvirus (KSHV) is a leading cause of malignancy in AIDS and current therapies are limited. Like all herpesviruses, KSHV infection can be…”
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Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome by Li, Shijun, Liu, Bing, Tan, Min, Juillard, Franceline, Szymula, Agnieszka, Álvarez, Ángel L, Van Sciver, Nicholas, George, Athira, Ramachandran, Akshaya, Raina, Komal, Tumuluri, Vinayak Sadasivam, Costa, Catarina N, Simas, J Pedro, Kaye, Kenneth M

“…Abstract To establish lifelong, latent infection, herpesviruses circularize their linear, double-stranded, DNA genomes through an unknown mechanism. Kaposi's…”
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MicroRNA-181a regulates IFN-γ expression in effector CD8+ T cell differentiation by Amado, Tiago, Amorim, Ana, Enguita, Francisco J., Romero, Paula V., Inácio, Daniel, de Miranda, Marta Pires, Winter, Samantha J., Simas, J. Pedro, Krueger, Andreas, Schmolka, Nina, Silva-Santos, Bruno, Gomes, Anita Q.

“…CD8 + T cells are key players in immunity against intracellular infections and tumors. The main cytokine associated with these protective responses is…”
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GLUT1‐mediated glucose uptake plays a crucial role during Plasmodium hepatic infection by Meireles, Patrícia, Sales‐Dias, Joana, Andrade, Carolina M., Mello‐Vieira, João, Mancio‐Silva, Liliana, Simas, J. Pedro, Staines, Henry M., Prudêncio, Miguel

“…Summary Intracellular pathogens have evolved mechanisms to ensure their survival and development inside their host cells. Here, we show that glucose is a…”
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Gammaherpesvirus Colonization of the Spleen Requires Lytic Replication in B Cells by Lawler, Clara, de Miranda, Marta Pires, May, Janet, Wyer, Orry, Simas, J Pedro, Stevenson, Philip G

“…Gammaherpesviruses infect lymphocytes and cause lymphocytic cancers. Murid herpesvirus-4 (MuHV-4), Epstein-Barr virus, and Kaposi's sarcoma-associated…”
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Cross-species conservation of episome maintenance provides a basis for in vivo investigation of Kaposi's sarcoma herpesvirus LANA by Habison, Aline C., Pires de Miranda, Marta, Beauchemin, Chantal, Tan, Min, A. Cerqueira, Sofia, Correia, Bruno, Ponnusamy, Rajesh, Usherwood, Edward J., McVey, Colin E., Simas, J Pedro, Kaye, Kenneth M.

“…Copyright: © 2017 Habison et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits…”
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Macrophages drive KSHV B cell latency by Szymula, Agnieszka, Samayoa-Reyes, Gabriela, Ogolla, Sidney, Liu, Bing, Li, Shijun, George, Athira, Van Sciver, Nicholas, Rochford, Rosemary, Simas, J. Pedro, Kaye, Kenneth M.

“…Kaposi’s sarcoma herpesvirus (KSHV) establishes lifelong infection and persists in latently infected B cells. Paradoxically, in vitro B cell infection is…”
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In Vivo Persistence of Chimeric Virus after Substitution of the Kaposi's Sarcoma-Associated Herpesvirus LANA DNA Binding Domain with That of Murid Herpesvirus 4 by Pires de Miranda, Marta, Quendera, Ana Patrícia, McVey, Colin E, Kaye, Kenneth M, Simas, J Pedro

“…The latency-associated nuclear antigen from Kaposi's sarcoma-associated herpesvirus (KSHV), kLANA, and its homolog from the murid herpesvirus 4 (MuHV-4),…”
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Murine Gammaherpesvirus 68 LANA Acts on Terminal Repeat DNA To Mediate Episome Persistence by HABISON, Aline C, BEAUCHEMIN, Chantal, PEDRO SIMAS, J, USHERWOOD, Edward J, KAYE, Kenneth M

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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SARS-CoV-2 decreases malaria severity in co-infected rodent models by Fraga, Ana, Mósca, Andreia F, Moita, Diana, Simas, J Pedro, Nunes-Cabaço, Helena, Prudêncio, Miguel

“…Coronavirus disease 2019 (COVID-19) and malaria, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and parasites, respectively, share…”
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Establishment of Murine Gammaherpesvirus latency in B cells is not a stochastic event by Decalf, Jérémie, Godinho-Silva, Cristina, Fontinha, Diana, Marques, Sofia, Simas, J Pedro

“…Copyright: © 2014 Decalf et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits…”
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Murid Gammaherpesvirus latency-associated protein M2 promotes the formation of conjugates between transformed B lymphoma cells and T helper cells by Fontinha, Diana, Lopes, Filipa B., Marques, Sofia, Simas, J Pedro

“…Copyright: © 2015 Fontinha et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits…”
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