Search Results - "Simargi, Shirleen"
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Hyaluronic acid conjugated nanoparticle delivery of siRNA against TWIST reduces tumor burden and enhances sensitivity to cisplatin in ovarian cancer
Published in Nanomedicine (01-06-2018)“…TWIST protein is critical to development and is activated in many cancers. TWIST regulates epithelial-mesenchymal transition, and is linked to angiogenesis,…”
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Chick chorioallantoic membrane assay as an in vivo model to study the effect of nanoparticle-based anticancer drugs in ovarian cancer
Published in Scientific reports (04-06-2018)“…New therapy development is critically needed for ovarian cancer. We used the chicken egg CAM assay to evaluate efficacy of anticancer drug delivery using…”
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Abstract 2024: Hyaluronic acid conjugated nanoparticle delivery of siTWIST reduces tumor burden and enhances chemosensitivity in ovarian cancer
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Purpose: TWIST is a transcription factor critical to embryonic development, and aberrantly activated in many cancers. It regulates…”
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Abstract 2152: Optimizing therapies for drug-resistant ovarian cancer stem cells using aCAM-PDX model
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Purpose: To develop rapidly operational CAM-PDX (chorioallantoic membrane-patient derived xenograft) tumor models that morphologically resemble human…”
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