Search Results - "Simard, Melissa"
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Adolescent Emotion Socialization: A Longitudinal Study of Friends' Responses to Negative Emotions
Published in Social development (Oxford, England) (01-05-2014)“…Although peer influences are thought to be critically important to adolescent development, there is a paucity of research investigating the emotion…”
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CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota
Published in Cell reports (Cambridge) (08-10-2019)“…Interleukin-17-producing γδ T (γδ17) cells play a central role in protective and pathogenic immune responses. However, the tissue-specific mechanisms that…”
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Rough-and-Tumble Play and the Development of Physical Aggression and Emotion Regulation: A Five-Year Follow-Up Study
Published in Journal of family violence (01-05-2010)“…This is a follow-up to a study demonstrating that rough-and-tumble play was related to physical aggression in the preschool years. Fathers reported on the…”
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Biological action of docosahexaenoic acid in a 3D tissue-engineered psoriatic skin model: Focus on the PPAR signaling pathway
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-12-2021)“…N-3 polyunsaturated fatty acids (n-3 PUFAs), and in particular docosahexaenoic acid (DHA), have many beneficial metabolic effects, including reducing epidermal…”
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Expression and Functions of the CB2 Receptor in Human Leukocytes
Published in Frontiers in pharmacology (22-02-2022)“…The cannabinoid CB 2 receptor was cloned from the promyeloid cell line HL-60 and is notably expressed in most, if not all leukocyte types. This relatively…”
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Infiltration of T Cells into a Three-Dimensional Psoriatic Skin Model Mimics Pathological Key Features
Published in International journal of molecular sciences (03-04-2019)“…Psoriasis is an autoimmune chronic dermatosis that is T cell-mediated, characterized by epidermal thickening, aberrant epidermal differentiation and…”
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Current knowledge of the implication of lipid mediators in psoriasis
Published in Frontiers in immunology (26-08-2022)“…The skin is an organ involved in several biological processes essential to the proper functioning of the organism. One of these essential biological functions…”
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α-Linolenic acid and linoleic acid modulate the lipidome and the skin barrier of a tissue-engineered skin model
Published in Acta biomaterialia (01-03-2022)“…Polyunsaturated fatty acids (PUFAs) play an important role in the establishment and the maintenance of the skin barrier function. However, the impact of their…”
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Docosahexaenoic Acid Modulates Paracellular Absorption of Testosterone and Claudin-1 Expression in a Tissue-Engineered Skin Model
Published in International journal of molecular sciences (03-12-2021)“…Healthy skin moLEdels produced by tissue-engineering often present a suboptimal skin barrier function as compared with normal human skin. Moreover, skin…”
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Origin of Serum Affects Quality of Engineered Tissues Produced by the Self-Assembly Approach
Published in Scientifica (Cairo) (01-01-2016)“…Despite the emergence of serum-free media for cell culture, the use of serum to supplement the culture media is still essential in order to produce engineered…”
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The Impact of the CB2 Cannabinoid Receptor in Inflammatory Diseases: An Update
Published in Molecules (Basel, Switzerland) (18-07-2024)“…The emergence of inflammatory diseases is a heavy burden on modern societies. Cannabis has been used for several millennia to treat inflammatory disorders such…”
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N-eicosapentaenoyl-ethanolamine decreases the proliferation of psoriatic keratinocytes in a reconstructed psoriatic skin model
Published in Scientific reports (26-07-2023)“…Psoriasis is an inflammatory skin disease that is characterized by keratinocyte hyperproliferation, abnormal epidermal differentiation and dysregulated lipid…”
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Development of a 3D psoriatic skin model optimized for infiltration of IL-17A producing T cells: Focus on the crosstalk between T cells and psoriatic keratinocytes
Published in Acta biomaterialia (01-12-2021)“…Psoriasis is a chronic inflammatory skin disease involving several cell types, including T cells, via the IL-23/IL-17 axis. IL-17A acts on the surrounding…”
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Biosynthesis and metabolism of endocannabinoids and their congeners from the monoacylglycerol and N-acyl-ethanolamine families
Published in Biochemical pharmacology (01-11-2022)“…[Display omitted] The endocannabinoids 2-arachidonoyl-glycerol (2-AG) and N-arachidonoyl-ethanolamine (AEA) are eicosanoids implicated in numerous…”
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Biosynthesis of resolvin D1, resolvin D2, and RCTR1 from 7,8(S,S)-epoxytetraene in human neutrophils and macrophages
Published in Proceedings of the National Academy of Sciences - PNAS (10-09-2024)“…While the acute inflammatory response to harmful stimuli is protective, unrestrained neutrophil swarming drives collateral tissue damage and inflammation…”
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Investigation of Omega-3 Polyunsaturated Fatty Acid Biological Activity in a Tissue-Engineered Skin Model Involving Psoriatic Cells
Published in Journal of investigative dermatology (01-10-2021)“…Clinical studies have shown that diets enriched with omega-3 (also know as n-3) polyunsaturated fatty acids could relieve the symptoms of patients with…”
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Pharmacological evidence that the inhibitory effects of prostaglandin E2 are mediated by the EP2 and EP4 receptors in human neutrophils
Published in Journal of leukocyte biology (29-05-2024)“…Prostaglandin E2 (PGE2) is a recognized inhibitor of granulocyte functions. However, most of the data supporting this was obtained when available…”
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A Tissue-Engineered Human Psoriatic Skin Model to Investigate the Implication of cAMP in Psoriasis: Differential Impacts of Cholera Toxin and Isoproterenol on cAMP Levels of the Epidermis
Published in International journal of molecular sciences (23-07-2020)“…Pathological and healthy skin models were reconstructed using similar culture conditions according to well-known tissue engineering protocols. For both models,…”
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Alpha-Linolenic Acid Modulates T Cell Incorporation in a 3D Tissue-Engineered Psoriatic Skin Model
Published in Cells (Basel, Switzerland) (30-04-2022)“…Psoriasis is an autoimmune skin disease with an increased number of leukocytes infiltrating the dermal and epidermal compartments compared with normal skin…”
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Modulation of the Lipid Profile of Reconstructed Skin Substitutes after Essential Fatty Acid Supplementation Affects Testosterone Permeability
Published in Cells (Basel, Switzerland) (25-09-2019)“…Skin models with efficient skin barrier function are required for percutaneous absorption studies. The contribution of media supplementation with n-3 and n-6…”
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