Search Results - "Simard, Gilles"

Oxidative Stress and Metabolic Pathologies: From an Adipocentric Point of View by Andriantsitohaina, Ramaroson, Martinez, Maria Carmen, Simard, Gilles, Le Lay, Soazig

“…Oxidative stress plays a pathological role in the development of various diseases including diabetes, atherosclerosis, or cancer. Systemic oxidative stress…”
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Leader-Follower (Dis) Similarity in Optimism: Its Effect on Followers’ Role Conflict, Vigor and Performance by Parent-Rocheleau, Xavier, Bentein, Kathleen, Simard, Gilles, Tremblay, Michel

“…The aim of this study was to investigate the effects of optimism similarity and dissimilarity between supervisors and subordinates on subordinates’ outcomes…”
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A Metabolomics Profiling of Glaucoma Points to Mitochondrial Dysfunction, Senescence, and Polyamines Deficiency by Leruez, Stéphanie, Marill, Alexandre, Bresson, Thomas, de Saint Martin, Grégoire, Buisset, Adrien, Muller, Jeanne, Tessier, Lydie, Gadras, Cédric, Verny, Christophe, Gohier, Philippe, Amati-Bonneau, Patrizia, Lenaers, Guy, Bonneau, Dominique, Simard, Gilles, Milea, Dan, Procaccio, Vincent, Reynier, Pascal, Chao de la Barca, Juan Manuel

“…To determine the plasma metabolomic signature of primary open-angle glaucoma (POAG). We compared the metabolomic profiles of plasma from individuals with POAG…”
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An immuno-lipidomic signature revealed by metabolomic and machine-learning approaches in labial salivary gland to diagnose primary Sjögren's syndrome by Urbanski, Geoffrey, Chabrun, Floris, Delattre, Estelle, Lacout, Carole, Davidson, Brittany, Blanchet, Odile, Chao de la Barca, Juan Manuel, Simard, Gilles, Lavigne, Christian, Reynier, Pascal

“…Assessing labial salivary gland exocrinopathy is a cornerstone in primary Sjögren's syndrome. Currently this relies on the histopathologic diagnosis of focal…”
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Tryptophane–kynurenine pathway in the remote ischemic conditioning mechanism by Bakhta, Oussama, Pascaud, Adrien, Dieu, Xavier, Beaumont, Justine, Kouassi Nzoughet, Judith, Kamel, Rima, Croyal, Mikaël, Tamareille, Sophie, Simard, Gilles, Chao de la Barca, Juan Manuel, Reynier, Pascal, Prunier, Fabrice, Mirebeau-Prunier, Delphine

“…The actual protective mechanisms underlying cardioprotection with remote ischemic conditioning (RIC) remain unclear. Recent data suggest that RIC induces…”
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Sexual Dimorphism of Metabolomic Profile in Arterial Hypertension by Goïta, Yaya, Chao de la Barca, Juan Manuel, Keïta, Asmaou, Diarra, Mamadou Bocary, Dembélé, Klétigui Casimir, Chabrun, Floris, Dramé, Boubacar Sidiki Ibrahim, Kassogué, Yaya, Diakité, Mahamadou, Mirebeau-Prunier, Delphine, Cissé, Bakary Mamadou, Simard, Gilles, Reynier, Pascal

“…Metabolomic studies have demonstrated the existence of biological signatures in blood of patients with arterial hypertension, but no study has hitherto…”
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Enhancement of the Anti-Angiogenic Effects of Delphinidin When Encapsulated within Small Extracellular Vesicles by Barkallah, Merwan, Nzoughet-Kouassi, Judith, Simard, Gilles, Thoulouze, Loric, Marze, Sébastien, Ropers, Marie-Hélène, Andriantsitohaina, Ramaroson

“…(1) Background: The anthocyanin delphinidin exhibits anti-angiogenic properties both in in vitro and in vivo angiogenesis models. However, in vivo delphinidin…”
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The Metabolomic Signature of Opa1 Deficiency in Rat Primary Cortical Neurons Shows Aspartate/Glutamate Depletion and Phospholipids Remodeling by Chao de la Barca, Juan Manuel, Arrázola, Macarena S., Bocca, Cinzia, Arnauné-Pelloquin, Laetitia, Iuliano, Olga, Tcherkez, Guillaume, Lenaers, Guy, Simard, Gilles, Belenguer, Pascale, Reynier, Pascal

“…Pathogenic variants of OPA1 , which encodes a dynamin GTPase involved in mitochondrial fusion, are responsible for a spectrum of neurological disorders sharing…”
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Phenotyping of circulating extracellular vesicles (EVs) in obesity identifies large EVs as functional conveyors of Macrophage Migration Inhibitory Factor by Amosse, Jérémy, Durcin, Maëva, Malloci, Marine, Vergori, Luisa, Fleury, Audrey, Gagnadoux, Frédéric, Dubois, Séverine, Simard, Gilles, Boursier, Jérôme, Hue, Olivier, Martinez, M. Carmen, Andriantsitohaina, Ramaroson, Le Lay, Soazig

“…Obesity-associated metabolic dysfunctions are linked to dysregulated production of adipokines. Accumulating evidence suggests a role for fat-derived…”
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Time window-dependent effect of perinatal maternal protein restriction on insulin sensitivity and energy substrate oxidation in adult male offspring by Agnoux, Aurore Martin, Antignac, Jean-Philippe, Simard, Gilles, Poupeau, Guillaume, Darmaun, Dominique, Parnet, Patricia, Alexandre-Gouabau, Marie-Cécile

“…Epidemiological and experimental evidence suggests that a suboptimal environment during perinatal life programs offspring susceptibility to the development of…”
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Delphinidin Inhibits Tumor Growth by Acting on VEGF Signalling in Endothelial Cells by Keravis, Thérèse, Favot, Laure, Abusnina, Abdurrazag A, Anton, Anita, Justiniano, Hélène, Soleti, Raffaella, Alabed Alibrahim, Eid, Simard, Gilles, Andriantsitohaina, Ramaroson, Lugnier, Claire

“…The vasculoprotective properties of delphinidin are driven mainly by its action on endothelial cells. Moreover, delphinidin displays anti-angiogenic properties…”
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A Metabolomic Profiling of Intra-Uterine Growth Restriction in Placenta and Cord Blood Points to an Impairment of Lipid and Energetic Metabolism by Chao de la Barca, Juan Manuel, Chabrun, Floris, Lefebvre, Tiphaine, Roche, Ombeline, Huetz, Noémie, Blanchet, Odile, Legendre, Guillaume, Simard, Gilles, Reynier, Pascal, Gascoin, Géraldine

“…(1) Background: Intrauterine growth restriction (IUGR) involves metabolic changes that may be responsible for an increased risk of metabolic and cardiovascular…”
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Metabolic Signature of Remote Ischemic Preconditioning Involving a Cocktail of Amino Acids and Biogenic Amines by Chao de la Barca, Juan Manuel, Bakhta, Oussama, Kalakech, Hussein, Simard, Gilles, Tamareille, Sophie, Catros, Véronique, Callebert, Jacques, Gadras, Cédric, Tessier, Lydie, Reynier, Pascal, Prunier, Fabrice, Mirebeau‐Prunier, Delphine

“…Background Remote ischemic preconditioning (RIPC) is an attractive therapeutic procedure for protecting the heart against ischemia/reperfusion injury. Despite…”
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The Influence of Psychological Contract Breach on Temporary Workers' Commitment and Behaviors: A Multiple Agency Perspective by Lapalme, Marie-Ève, Simard, Gilles, Tremblay, Michel

“…Purpose The purpose of this study was to examine the influence of psychological contract breach on the commitment and behaviors of temporary workers engaged in…”
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Predictive Factors of Oxaliplatin Neurotoxicity: The Involvement of the Oxalate Outcome Pathway by GAMELIN, Laurence, CAPITAIN, Olivier, MOREL, Alain, DUMONT, Agnes, TRAORE, Sory, ANNE, Le Bouil, GILLES, Simard, BOISDRON-CELLE, Michele, GAMELINL, Erick

“…Purpose: Oxaliplatin displays a frequent dose-limiting neurotoxicity due to its interference with neuron voltage-gated sodium channels through one of its…”
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Aromatic L-Amino Acid Decarboxylase Deficiency Is a Cause of Long-Fasting Hypoglycemia by Arnoux, Jean-Baptiste, Damaj, Léna, Napuri, Sylvia, Serre, Valérie, Hubert, Laurence, Cadoudal, Marylène, Simard, Gilles, Ceballos, Irène, Christa, Laurence, de Lonlay, Pascale

“…Objective/Context: Long-fasting hypoglycemia in children may be induced by neurotransmitter disorders. Case Report: A 5-year-old girl with a medical history of…”
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A Data Mining Metabolomics Exploration of Glaucoma by Kouassi Nzoughet, Judith, Guehlouz, Khadidja, Leruez, Stéphanie, Gohier, Philippe, Bocca, Cinzia, Muller, Jeanne, Blanchet, Odile, Bonneau, Dominique, Simard, Gilles, Milea, Dan, Procaccio, Vincent, Lenaers, Guy, Chao de la Barca, Juan M, Reynier, Pascal

“…Glaucoma is an age related disease characterized by the progressive loss of retinal ganglion cells, which are the neurons that transduce the visual information…”
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Can “Temps” Secure Future Employment? Investigating the Relationship Between Proactive Behaviors and Employers’ Rehiring Decision by Lapalme, Marie-Ève, Doucet, Olivier, Gill, Andréa, Simard, Gilles

“…This study examines how the adoption of proactive socialization behaviors by temporary agency workers is related to contract renewal intention of the…”
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Propionyl-L-carnitine corrects metabolic and cardiovascular alterations in diet-induced obese mice and improves liver respiratory chain activity by Mingorance, Carmen, Duluc, Lucie, Chalopin, Matthieu, Simard, Gilles, Ducluzeau, Pierre-Henri, Herrera, Maria Dolores, Alvarez de Sotomayor, Maria, Andriantsitohaina, Ramaroson

“…Obesity is a primary contributor to acquired insulin resistance leading to the development of type 2 diabetes and cardiovascular alterations. The carnitine…”
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A Metabolomic Signature of Ischemic Stroke Showing Acute Oxidative and Energetic Stress by Djite, Moustapha, Chao de la Barca, Juan Manuel, Bocca, Cinzia, Gaye, Ndiaga Matar, Barry, Néné Oumou Kesso, Mbacke, Mame Ndoumbé, Cissé, Ousmane, Kandji, Pape Matar, Thioune, Ndèye Marème, Coly-Gueye, Najah Fatou, Ndour, El Hadji Malick, Gueye-Tall, Fatou, Diop, Amadou Gallo, Simard, Gilles, Mirebeau-Prunier, Delphine, Gueye, Papa Madieye, Reynier, Pascal

“…Metabolomics is a powerful data-driven tool for in-depth biological phenotyping that could help identify the specific metabolic profile of cryptogenic strokes,…”
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