Search Results - "Sima Mansoori"

Molecular Mechanisms of Apoptosis and Roles in Cancer Development and Treatment by Goldar, Samira, Khaniani, Mahmoud Shekari, Derakhshan, Sima Mansoori, Baradaran, Behzad

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Narrower insight to SIRT1 role in cancer: A potential therapeutic target to control epithelial–mesenchymal transition in cancer cells by Choupani, Jalal, Mansoori Derakhshan, Sima, Bayat, Sahar, Alivand, Mohammad Reza, Shekari Khaniani, Mahmoud

“…The epithelial–mesenchymal transition (EMT) is a highly networked cellular process which involves cell transition from the immotile epithelial to the motile…”
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Downregulation of HDAC2 and HDAC3 via oleuropein as a potent prevention and therapeutic agent in MCF‐7 breast cancer cells by Bayat, Sahar, Mansoori Derakhshan, Sima, Mansoori Derakhshan, Neda, Shekari Khaniani, Mahmoud, Alivand, Mohammad Reza

“…Breast cancer is the most common malignancy in the world with the highest rate of morbidity and mortality. Due to the several side effects of chemotherapy and…”
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A new insight on serum microRNA expression as novel biomarkers in breast cancer patients by Bahmanpour, Zahra, Sheervalilou, Roghayeh, Choupani, Jalal, Shekari Khaniani, Mahmoud, Montazeri, Vahid, Mansoori Derakhshan, Sima

“…Breast cancer (BC) is one of the widespread lethal diseases affecting a large number of women worldwide. As such, employing and identifying significant markers…”
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The hopeful anticancer role of oleuropein in breast cancer through histone deacetylase modulation by Mansouri, Neda, Alivand, Mohammad Reza, Bayat, Sahar, Khaniani, Mahmoud Shekari, Derakhshan, Sima Mansoori

“…Breast cancer (BC) is one of the most common cancers among women worldwide. Genetic, epigenetic, and environmental factors play a crucial role in BC…”
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A novel missense variant in ESRRB gene causing autosomal recessive non-syndromic hearing loss: in silico analysis of a case by Ghasemnejad, Tohid, Shekari Khaniani, Mahmoud, Nouri Nojadeh, Jafar, Mansoori Derakhshan, Sima

“…Hereditary hearing loss (HHL) is a common heterogeneous disorder affecting all ages, ethnicities, and genders. The most common form of HHL is autosomal…”
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An update of common autosomal recessive non-syndromic hearing loss genes in Iranian population by Ghasemnejad, Tohid, Shekari Khaniani, Mahmoud, Zarei, Fatemeh, Farbodnia, Mina, Mansoori Derakhsahan, Sima

“…Abstract Autosomal-recessive genes are responsible for about 80% of the hereditary non-syndromic hearing loss (NSHL) cases. In Iran, due to consanguineous…”
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A Novel Pathogenic Mutation in WNK1 Gene Causing HSAN Type II in Three Siblings by Naghinejad, Maryam, Ebrahimi, Amir, Shekari Khaniani, Mahmoud, Mansoori Derakhshan, Sima

“…Hereditary sensory and autonomic neuropathy (HSAN) is a rare genetic disorder that primarily affects the peripheral nervous system, leading to a progressive…”
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The impact of microRNAs on the resistance of breast cancer subtypes to chemotherapy by Ebrahimi, Amir, Bakhshaei Shahrebabaki, Peyman, Fouladi, Hadi, Mansoori Derakhshan, Sima

“…Breast cancer (BC) formation is primarily influenced by genetics, epigenetics and environmental factors. Aberrant Genetics and epigenetics leads to a condition…”
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miR‐449a: A Promising Biomarker and Therapeutic Target in Cancer and Other Diseases by Barati, Tahereh, Mirzaei, Zohreh, Ebrahimi, Amir, Shekari Khaniani, Mahmoud, Mansoori Derakhshan, Sima

“…In the regulation of gene expression, epigenetic factors like non-coding RNAs (ncRNAs) play an equal role in genetics. The role of microRNAs (miRNAs), which…”
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Potential brain biomarkers in patients with Autism spectrum syndrome by Ghavi, Davood, Ebrahimi, Amir, Forouzandeh, Zahra, Shekari Khaniani, Mahmoud, Mansoori Derakhshan, Sima

“…Autism spectrum disorder (ASD) is referred as a cluster of neurodevelopmental disorders with relatively high incidence. ASD is believed to be a multifactorial…”
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HDACis (class I), cancer stem cell, and phytochemicals: Cancer therapy and prevention implications by Bayat, Sahar, Shekari Khaniani, Mahmoud, Choupani, Jalal, Alivand, Mohammad Reza, Mansoori Derakhshan, Sima

“…Epigenetics is independent of the sequence events that physically affect the condensing of chromatin and genes expression. The unique epigenetic memories of…”
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Restoration of correct splicing in IVSI-110 mutation of β-globin gene with antisense oligonucleotides: implications and applications in functional assay development by Derakhshan, Sima Mansoori, Khaniani, Mahmoud Shekari

“…The use of antisense oligonucleotides (AOs) to restore normal splicing by blocking the recognition of aberrant splice sites by the spliceosome represents an…”
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Differential Expression Pattern of Epithelial Mesenchymal Transition Gens: AXL, GAS6, Claudin-1, and Cofilin-1, in Different Stages of Epithelial Ovarian Cancer by Hassani, Elham, Shekari Khaniani, Mahmood, Saffari, Mojtaba, Emami Razavi, Amirnader, Shirkoohi, Reza, Mansoori Derakhshan, Sima

“…Epithelial ovarian cancer (EOC), is the fatal form of gynecological cancer. Almost 70% of ovarian cancer patients are detected at an advanced stage (III-IV)…”
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Evaluation of Association Between HLA Class II DR4-DQ8 Haplotype and Type I Diabetes Mellitus in Children of East Azerbaijan State of Iran by Sohrabi, Nasrin, Khaniani, Mahmoud Shekari, Derakhshan, Sima Mansoori

“…Purpose: Association between HLA-DR4–DQ8 haplotype and type 1 Diabetes Mellitus (DM-1A) was investigated in children of East Azerbaijan state of Iran because…”
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The HLA-G 14-bp Insertion/ Deletion Polymorphism in Recurrent Spontaneous Abortion among Iranian Women by Afkhami, Fatemeh, Khaniani, Mahmoud Shekari, Farzadi, Layia, Paknejad, Zeynab, Derakhshan, Sima Mansoori

“…HLA-G is a non-classical HLA class Ib molecule with limited protein variability generated by alternative splicing. HLA-G displays immunotolerant properties and…”
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The worldwide frequency of MYO15A gene mutations in patients with non-syndromic hearing loss: A meta-analysis by Farjami, Mahsa, Assadi, Reza, Afzal Javan, Fahimeh, Alimardani, Malihe, Eslami, Saeid, Mansoori Derakhshan, Sima, Eslahi, Atieh, Mojarrad, Majid

“…MYO15A is the third most crucial gene in hereditary sensorineural hearing loss after GJB2 and SLC26A4 . In the present study, we reviewed the prevalence of…”
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Molecular Mechanisms of Apoptosis and Roles in Cancer Development and Treatment by Goldar, Samira, Khaniani, Mahmoud Shekari, Derakhshan, Sima Mansoori, Baradaran, Behzad

“…Programmed cell death (PCD) or apoptosis is a mechanism which is crucial for all multicellular organisms to control cell proliferation and maintain tissue…”
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Cloning of Soluble Human Stem Cell Factor in pET-26b(+) Vector by Asghari, Salman, Khaniani, Mahmoud Shekari, Darabi, Masood, Derakhshan, Sima Mansoori

“…Purpose: Stem cell factor (SCF) plays an important role in the survival, proliferation and differentiation of hematopoietic stem cells and progenitor cells…”
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NUCB2/Nesfatin-1: A Potent Meal Regulatory Hormone and its Role in Diabetes by Khalili, Soodabeh, Shekari Khaniani, Mahmoud, Afkhami, Fatemeh, Mansoori Derakhshan, Sima

“…Nesfatin-1, a newly discovered calcium and DNA binding peptide, originate from nucleobindin 2 (NUCB2) precursors and expressed by central and peripheral…”
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