Search Results - "Sima, V."

MiR-486 and miR-92a Identified in Circulating HDL Discriminate between Stable and Vulnerable Coronary Artery Disease Patients by Niculescu, Loredan S, Simionescu, Natalia, Sanda, Gabriela M, Carnuta, Mihaela G, Stancu, Camelia S, Popescu, Andreea C, Popescu, Mihaela R, Vlad, Adelina, Dimulescu, Doina R, Simionescu, Maya, Sima, Anca V

“…Small non-coding microRNAs (miRNAs) are implicated in gene regulation, including those involved in coronary artery disease (CAD). Our aim was to identify…”
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Elevated Levels of Circulating lncRNAs LIPCAR and MALAT1 Predict an Unfavorable Outcome in Acute Coronary Syndrome Patients by Barbalata, Teodora, Niculescu, Loredan S, Stancu, Camelia S, Pinet, Florence, Sima, Anca V

“…Coronary artery disease (CAD) is a leading cause of mortality worldwide. In this study, we aimed to assess the potential of plasma long non-coding RNAs…”
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Aggregated LDL turn human macrophages into foam cells and induce mitochondrial dysfunction without triggering oxidative or endoplasmic reticulum stress by Sanda, Gabriela M, Stancu, Camelia S, Deleanu, Mariana, Toma, Laura, Niculescu, Loredan S, Sima, Anca V

“…Uptake of modified lipoproteins by macrophages turns them into foam cells, the hallmark of the atherosclerotic plaque. The initiation and progression of…”
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Increased miR-142 Levels in Plasma and Atherosclerotic Plaques from Peripheral Artery Disease Patients with Post-Surgery Cardiovascular Events by Barbalata, Teodora, Moraru, Oriana E, Stancu, Camelia S, Devaux, Yvan, Simionescu, Maya, Sima, Anca V, Niculescu, Loredan S

“…There is an intensive effort to identify biomarkers to predict cardiovascular disease evolution. We aimed to determine the potential of microRNAs to predict…”
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Mitochondrial DNA Together with miR-142-3p in Plasma Can Predict Unfavorable Outcomes in Patients after Acute Myocardial Infarction by Barbalata, Teodora, Scarlatescu, Alina I, Sanda, Gabriela M, Toma, Laura, Stancu, Camelia S, Dorobantu, Maria, Micheu, Miruna M, Sima, Anca V, Niculescu, Loredan S

“…Myocardial infarction is one of the leading causes of death worldwide, despite numerous efforts to find efficient prognostic biomarkers and treatment targets…”
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Influence of Biomarkers on Mortality among Patients with Hepatic Metastasis of Colorectal Cancer Treated with FOLFOX/CAPOX and FOLFIRI/CAPIRI, Including Anti-EGFR and Anti-VEGF Therapies by Popovici, Dorel, Stanisav, Cristian, Sima, Laurentiu V, Negru, Alina, Murg, Sergiu Ioan, Carabineanu, Adrian

“…Colorectal cancer is a major global health concern, with a significant increase in morbidity and mortality rates associated with metastatic stages. This study…”
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Regulation of microRNAs in high-fat diet induced hyperlipidemic hamsters by Barbalata, Teodora, Zhang, Lu, Dulceanu, Madalina D., Stancu, Camelia S., Devaux, Yvan, Sima, Anca V., Niculescu, Loredan S.

“…Dyslipidemia is a documented risk factor for cardiovascular diseases and other metabolic disorders. Therefore, the analysis of hyperlipidemia (HL)-related…”
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Dysfunctional high-density lipoproteins have distinct composition, diminished anti-inflammatory potential and discriminate acute coronary syndrome from stable coronary artery disease patients by Carnuta, Mihaela G., Stancu, Camelia S., Toma, Laura, Sanda, Gabriela M., Niculescu, Loredan S., Deleanu, Mariana, Popescu, Andreea C., Popescu, Mihaela R., Vlad, Adelina, Dimulescu, Doina R., Simionescu, Maya, Sima, Anca V.

“…There is a stringent need to find means for risk stratification of coronary artery diseases (CAD) patients. We aimed at identifying alterations of plasma…”
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Foam cell‐derived 4‐hydroxynonenal induces endothelial cell senescence in a TXNIP‐dependent manner by Riahi, Yael, Kaiser, Nurit, Cohen, Guy, Abd‐Elrahman, Ihab, Blum, Galia, Shapira, Oz M., Koler, Tomer, Simionescu, Maya, Sima, Anca V., Zarkovic, Neven, Zarkovic, Kamelija, Orioli, Marica, Aldini, Giancarlo, Cerasi, Erol, Leibowitz, Gil, Sasson, Shlomo

“…Vascular endothelial cell (VEC) senescence is considered an early event in the development of atherosclerotic lesions. Stressful stimuli, in particular…”
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Hyperglycemia Determines Increased Specific MicroRNAs Levels in Sera and HDL of Acute Coronary Syndrome Patients and Stimulates MicroRNAs Production in Human Macrophages by Simionescu, Natalia, Niculescu, Loredan S, Carnuta, Mihaela G, Sanda, Gabriela M, Stancu, Camelia S, Popescu, Andreea C, Popescu, Mihaela R, Vlad, Adelina, Dimulescu, Doina R, Simionescu, Maya, Sima, Anca V

“…We aimed to determine the levels of microRNAs (miRNAs) in sera and HDL of acute coronary syndrome (ACS) compared to stable angina (SA) patients with/without…”
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Pancreaticoduodenectomy with Anatomical Vascular Variant in Groove Pancreatitis-A Case Report by Breaza, Gelu M, Dan, Radu G, Hut, Florin E, Baderca, Flavia, Cretu, Octavian M, Sima, Laurentiu V

“…Groove pancreatitis represents a chronic focal form of pancreatitis affecting the zone between the pancreatic head and the duodenal "C" loop, known as the…”
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Oscillating Glucose Induces the Increase in Inflammatory Stress through Ninjurin-1 Up-Regulation and Stimulation of Transport Proteins in Human Endothelial Cells by Toma, Laura, Sanda, Gabriela M, Stancu, Camelia S, Niculescu, Loredan S, Raileanu, Mina, Sima, Anca V

“…Clinical data implicate fluctuations of high levels of plasma glucose in cardiovascular diseases. Endothelial cells (EC) are the first cells of the vessel wall…”
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Irreversibly glycated LDL induce oxidative and inflammatory state in human endothelial cells; added effect of high glucose by Toma, Laura, Stancu, Camelia S., Botez, Gabriela M., Sima, Anca V., Simionescu, Maya

“…In diabetes, hyperglycemia and the associated formation of advanced glycation end-products (AGE) and AGE-modified low density lipoproteins (AGE-LDL) can…”
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Anti-oxidant and anti-inflammatory mechanisms of amlodipine action to improve endothelial cell dysfunction induced by irreversibly glycated LDL by Toma, Laura, Stancu, Camelia S., Sanda, Gabriela M., Sima, Anca V.

“…[Display omitted] ► Amlodipine antioxidant and antiinflammatory ability to repair endothelial dysfunction. ► Reduced p22phox, NOX4, iNOS expression, NADPHox…”
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CRISPR/dCas9 Transcriptional Activation of Endogenous Apolipoprotein AI and Paraoxonase 1 in Enterocytes Alleviates Endothelial Cell Dysfunction by Toma, Laura, Barbălată, Teodora, Sanda, Gabriela M, Niculescu, Loredan S, Sima, Anca V, Stancu, Camelia S

“…Atherosclerosis is the main cause of cardiovascular diseases with high prevalence worldwide. A promising therapeutic strategy to reverse atherosclerotic…”
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A hyperlipidemic diet induces structural changes in cerebral blood vessels by Constantinescu, Elena, Safciuc, Florentina, Sima, Anca V

“…The cerebrovascular pathology is an important contributor to the death rate presently. Hyperlipidemia , an established risk factor for cardiovascular diseases,…”
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Microhardness study of CdZnTeSe crystals for X-ray and gamma ray radiation detectors by Moravec, P., Franc, J., Dedic, V., Minarik, P., Elhadidy, H., Sima, V., Grill, R., Roy, U.

“…It is known that dislocations can act as electrically active shallow levels and influence the charge collection efficiency. The goal of the presented work is…”
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Novel molecular mechanisms by which ginger extract reduces the inflammatory stress in TNFα – activated human endothelial cells; decrease of Ninjurin-1, TNFR1 and NADPH oxidase subunits expression by Toma, Laura, Raileanu, Mina, Deleanu, Mariana, Stancu, Camelia S., Sima, Anca V.

“…[Display omitted] •GEx diminishes MCP-1, VCAM-1 and monocyte adhesion in TNFα-exposed HEC.•GEx anti-inflammatory action was correlated with the decrease of…”
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Probiotics administration or the high-fat diet arrest modulates microRNAs levels in hyperlipidemic hamsters by Niculescu, Loredan S., Dulceanu, Madalina D., Stancu, Camelia S., Carnuta, Mihaela G., Barbalata, Teodora, Sima, Anca V.

“…[Display omitted] •Probiotics and high-fat diet (HFD) arrest reduce miRNA levels in HL hamsters liver.•HFD arrest restores cholesterol metabolism-related…”
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Vascular endothelium in atherosclerosis by Sima, Anca V, Stancu, Camelia S, Simionescu, Maya

“…Their strategic location between blood and tissue and their constitutive properties allow endothelial cells (EC) to monitor the transport of plasma molecules,…”
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