Search Results - "Simões‐Wüst, A. Paula"

Induction of apoptosis and chemosensitization of mesothelioma cells by Bcl‐2 and Bcl‐xL antisense treatment by Hopkins‐Donaldson, Sally, Cathomas, Richard, Simões‐Wüst, A. Paula, Kurtz, Stefanie, Belyanskya, Larisa, Stahel, Rolf A., Zangemeister‐Wittke, Uwe

“…Our study was designed to investigate the role of the anti‐apoptotic proteins Bcl‐2 and Bcl‐xL in the chemoresistance of cells derived from malignant pleural…”
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Bcl-2/bcl-xL bispecific antisense treatment sensitizes breast carcinoma cells to doxorubicin, paclitaxel and cyclophosphamide by SIMOES-WÜST, A. Paula, SCHÜRPF, Thomas, HALL, Jonathan, STAHEL, Rolf A, ZANGEMEISTER-WITTKE, Uwe

“…Overexpression of the anti-apoptotic proteins bcl-2 and bcl-xL is implicated in breast cancer development, tumor progression and drug resistance. Here we…”
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Use of complementary and alternative medicine by children in Europe: Published data and expert perspectives by Zuzak, Tycho J, Boňková, Johanna, Careddu, Domenico, Garami, Miklós, Hadjipanayis, Adamos, Jazbec, Janez, Merrick, Joav, Miller, Joyce, Ozturk, Candan, Persson, Ingrid A.L, Petrova, Guenka, Saz Peiró, Pablo, Schraub, Simon, Simões-Wüst, A. Paula, Steinsbekk, Aslak, Stockert, Karin, Stoimenova, Assena, Styczynski, Jan, Tzenova-Savova, Alexandra, Ventegodt, Søren, Vlieger, Arine M, Längler, Alfred

“…Summary Introduction Few data document the use of complementary and alternative medicine (CAM) in Europe, with even fewer investigating use by children…”
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A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy by OLIE, R. A, SIMOES-WÜST, A. P, BAUMANN, B, LEECH, S. H, FABBRO, D, STAHEL, R. A, ZANGEMEISTER-WITTKE, U

“…Survivin, an inhibitor of apoptosis protein, deserves attention as a selective target for cancer therapy because it lacks expression in differentiated adult…”
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Influence of organic diet on the amount of conjugated linoleic acids in breast milk of lactating women in the Netherlands by Rist, Lukas, Mueller, André, Barthel, Christiane, Snijders, Bianca, Jansen, Margje, Simões-Wüst, A. Paula, Huber, Machteld, Kummeling, Ischa, von Mandach, Ursula, Steinhart, Hans, Thijs, Carel

“…The aim of the present study was to find out whether the incorporation of organic dairy and meat products in the maternal diet affects the contents of the…”
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Activity of a Novel bcl-2/bcl-xL-Bispecific Antisense Oligonucleotide Against Tumors of Diverse Histologic Origins by Gautschi, Oliver, Tschopp, Stefan, Olie, Robert A., Leech, Siân H., Simões-Wüst, A. Paula, Ziegler, Annemarie, Baumann, Bettina, Odermatt, Bernhard, Hall, Jonathan, Stahel, Rolf A., Zangemeister-Wittke, Uwe

“…Background: Increased expression of the anti-apoptotic proteins Bcl-2 and Bcl-xL is involved in the development and progression of many tumors. We recently…”
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Induction of apoptosis in lung‐cancer cells following bcl‐xL anti‐sense treatment by Leech, Siân H., Olie, Robert A., Gautschi, Oliver, Simões‐Wüst, A. Paula, Tschopp, Stefan, Häner, Robert, Hall, Jonathan, Stahel, Rolf A., Zangemeister‐Wittke, Uwe

“…Over‐expression of the anti‐apoptotic protein bcl‐xL is frequently found in lung cancer where it potentially contributes to tumor development, progression and…”
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bcl‐xl antisense treatment induces apoptosis in breast carcinoma cells by Simões‐Wüst, A. Paula, Olie, Robert A., Gautschi, Oliver, Leech, Siân H., Häner, Robert, Hall, Jonathan, Fabbro, Doriano, Stahel, Rolf A., Zangemeister‐Wittke, Uwe

“…Upregulated expression of bcl‐xL is involved in the initiation and progression of breast cancer by inhibiting tumor cell apoptosis. Here we describe the use of…”
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A Novel Bispecific Antisense Oligonucleotide Inhibiting Both bcl-2 and bcl-xL Expression Efficiently Induces Apoptosis in Tumor Cells by Uwe Zangemeister-Wittke, Siân H. Leech, Robert A. Olie, A. Paula Simões-Wüst, Oliver Gautschi, Gerd H. Luedke, François Natt, Robert Häner, Pierre Martin, Jonathan Hall, Carlo M. Nalin, Rolf A. Stahel

“…Bcl-2 and Bcl-xL are inhibitors of apoptosis frequently overexpressed in solid tumors. The bcl-2 and bcl-xL mRNAs share a region of homology comprising…”
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A functionally improved locked nucleic acid antisense oligonucleotide inhibits Bcl-2 and Bcl-xL expression and facilitates tumor cell apoptosis by Simões-Wüst, A Paula, Hopkins-Donaldson, Sally, Sigrist, Brigitte, Belyanskaya, Larisa, Stahel, Rolf A, Zangemeister-Wittke, Uwe

“…We previously reported the Bcl-2/Bcl-xL-bispecific activity of the 2'-O-(2-methoxy)ethyl (2'-MOE)-modified gapmer antisense oligonucleotide 4625. This…”
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Prolonged cytotoxic effect of aqueous extracts from dried viscum album on bladder cancer cells by Hunziker-Basler, N, Zuzak, T J, Eggenschwiler, J, Rist, L, Simões-Wüst, A P, Viviani, A

“…Aqueous extracts from whole dried mistletoe (Viscum album L., Iscucin) are often used in anti-cancer treatment. We studied the effect of extracts obtained from…”
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Mistletoe lectin is not the only cytotoxic component in fermented preparations of Viscum album from white fir (Abies pectinata) by Eggenschwiler, Jenny, von Balthazar, Leopold, Stritt, Bianca, Pruntsch, Doreen, Ramos, Mac, Urech, Konrad, Rist, Lukas, Simões-Wüst, A Paula, Viviani, Angelika

“…Preparations of mistletoe (Viscum album) are the form of cancer treatment that is most frequently used in the complementary medicine. Previous work has shown…”
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Activity of a Novel bcl-2/bcl-xL-Bispecific Antisense Oligonucleotide Against Tumors of Diverse Histologic Origins: p. 472 by Gautschi, Oliver, Tschopp, Stefan, Olie, Robert A, Leech, Sian H, A. Paula Simoes-Wust, Ziegler, Annemarie, Baumann, Bettina, Odermatt, Bernhard, Hall, Jonathan, Stahel, Rolf A, Zangemeister-Wittke, Uwe

“…Background: Increased expression of the anti-apoptotic proteins Bcl-2 and Bcl-xL is involved in the development and progression of many tumors. We recently…”
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