Search Results - "Simões, Sérgio N"
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Alteration of circulating ACE2-network related microRNAs in patients with COVID-19
Published in Scientific reports (12-06-2024)“…Angiotensin converting enzyme 2 (ACE2) serves as the primary receptor for the SARS-CoV-2 virus and has implications for the functioning of the cardiovascular…”
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Thrombosis-related circulating miR-16-5p is associated with disease severity in patients hospitalised for COVID-19
Published in RNA biology (31-12-2022)“…SARS-CoV-2 tropism for the ACE2 receptor, along with the multifaceted inflammatory reaction, is likely to drive the generalized hypercoagulable and thrombotic…”
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ACE2 Interaction Networks in COVID-19: A Physiological Framework for Prediction of Outcome in Patients with Cardiovascular Risk Factors
Published in Journal of clinical medicine (21-11-2020)“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection (coronavirus disease 2019; COVID-19) is associated with adverse outcomes in patients…”
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NERI: network-medicine based integrative approach for disease gene prioritization by relative importance
Published in BMC bioinformatics (16-12-2015)“…Complex diseases are characterized as being polygenic and multifactorial, so this poses a challenge regarding the search for genes related to them. With the…”
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Maternal immune response during pregnancy and neurodevelopmental outcomes: A longitudinal approach
Published in Brain, behavior, & immunity. Health (01-10-2024)“…The neurodevelopment of the offspring is suggested to be influenced by the maternal immune system's responses throughout pregnancy, which in turn is also…”
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Abstract 625: Alteration Of Circulating Ace2-network Related Micrornas In Patients With Covid-19
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2023)“…Abstract only ACE2 interaction network caused by virus infection can affect the expression levels of miRNAs and influence severity of COVID19. This study aimed…”
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Network-Based Disease Gene Prioritization by Hitting Time Analysis
Published in 2014 IEEE International Conference on Bioinformatics and Bioengineering (01-11-2014)“…Many methods have been published to prioritize genes using network theory. By using protein-protein interaction (PPI) data, it is possible to use mathematical…”
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