Search Results - "Sim, Iain"

Predicting Atrial Fibrillation Recurrence by Combining Population Data and Virtual Cohorts of Patient-Specific Left Atrial Models by Roney, Caroline H., Sim, Iain, Yu, Jin, Beach, Marianne, Mehta, Arihant, Alonso Solis-Lemus, Jose, Kotadia, Irum, Whitaker, John, Corrado, Cesare, Razeghi, Orod, Vigmond, Edward, Narayan, Sanjiv M., O’Neill, Mark, Williams, Steven E., Niederer, Steven A.

“…Current ablation therapy for atrial fibrillation is suboptimal, and long-term response is challenging to predict. Clinical trials identify bedside properties…”
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Quantifying atrial anatomy uncertainty from clinical data and its impact on electro-physiology simulation predictions by Corrado, Cesare, Razeghi, Orod, Roney, Caroline, Coveney, Sam, Williams, Steven, Sim, Iain, O’Neill, Mark, Wilkinson, Richard, Oakley, Jeremy, Clayton, Richard H., Niederer, Steven

“…•Quantification of the left atrial shape uncertainty.•Probabilistic approach.•Quantify the impact of the shape uncertainty on numerical simulations.•Medical…”
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In silico Comparison of Left Atrial Ablation Techniques That Target the Anatomical, Structural, and Electrical Substrates of Atrial Fibrillation by Roney, Caroline H, Beach, Marianne L, Mehta, Arihant M, Sim, Iain, Corrado, Cesare, Bendikas, Rokas, Solis-Lemus, Jose A, Razeghi, Orod, Whitaker, John, O'Neill, Louisa, Plank, Gernot, Vigmond, Edward, Williams, Steven E, O'Neill, Mark D, Niederer, Steven A

“…Catheter ablation therapy for persistent atrial fibrillation (AF) typically includes pulmonary vein isolation (PVI) and may include additional ablation lesions…”
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OpenEP: A Cross-Platform Electroanatomic Mapping Data Format and Analysis Platform for Electrophysiology Research by Williams, Steven E, Roney, Caroline H, Connolly, Adam, Sim, Iain, Whitaker, John, O'Hare, Daniel, Kotadia, Irum, O'Neill, Louisa, Corrado, Cesare, Bishop, Martin, Niederer, Steven A, Wright, Matt, O'Neill, Mark, Linton, Nick W F

“…Electroanatomic mapping systems are used to support electrophysiology research. Data exported from these systems is stored in proprietary formats which are…”
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Secondary Stroke Prevention Following Embolic Stroke of Unknown Source in the Absence of Documented Atrial Fibrillation: A Clinical Review by Kotadia, Irum D., Sim, Iain, Mukherjee, Rahul, O’Hare, Daniel, Chiribiri, Amedeo, Birns, Jonathan, Bhalla, Ajay, O’Neill, Mark, Williams, Steven E.

“…Abstract Approximately one‐third of ischemic strokes are classified as cryptogenic strokes. The risk of stroke recurrence in these patients is significantly…”
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Marked enhancement of the immune response to BioThrax® (Anthrax Vaccine Adsorbed) by the TLR9 agonist CPG 7909 in healthy volunteers by Rynkiewicz, Dianna, Rathkopf, Melinda, Sim, Iain, Waytes, A. Thomas, Hopkins, Robert J, Giri, Lallan, DeMuria, Deborah, Ransom, Janet, Quinn, James, Nabors, Gary S, Nielsen, Carl J

“…Abstract Immunization with BioThrax® (Anthrax Vaccine Adsorbed) is a safe and effective means of preventing anthrax. Animal studies have demonstrated that the…”
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High Prevalence of New Clinically Significant Findings in Patients With Embolic Stroke of Unknown Source Evaluated by Cardiac Magnetic Resonance Imaging by Kotadia, Irum D, O'Dowling, Robert, Aboagye, Akosua, Crawley, Richard J, Bodagh, Neil, Gharaviri, Ali, O'Hare, Daniel, Solis-Lemus, Jose Alonso, Roney, Caroline H, Sim, Iain, Ramsey, Deborah, Newby, David, Chiribiri, Amedeo, Plein, Sven, Sztriha, Laszlo, Scott, Paul, Masci, Pier-Giorgio, Harrison, James, Williams, Michelle C, Birns, Jonathan, Somerville, Peter, Bhalla, Ajay, Niederer, Steven, O'Neill, Mark, Williams, Steven E

“…Embolic stroke of unknown source (ESUS) accounts for 1 in 6 ischemic strokes. Current guidelines do not recommend routine cardiac magnetic resonance (CMR)…”
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Time-Averaged Wavefront Analysis Demonstrates Preferential Pathways of Atrial Fibrillation, Predicting Pulmonary Vein Isolation Acute Response by Roney, Caroline H, Child, Nicholas, Porter, Bradley, Sim, Iain, Whitaker, John, Clayton, Richard H, Laughner, Jacob I, Shuros, Allan, Neuzil, Petr, Williams, Steven E, Razavi, Reza S, O'Neill, Mark, Rinaldi, Christopher A, Taggart, Peter, Wright, Matt, Gill, Jaswinder S, Niederer, Steven A

“…Electrical activation during atrial fibrillation (AF) appears chaotic and disorganised, which impedes characterisation of the underlying substrate and…”
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Standardised computed tomographic assessment of left atrial morphology and tissue thickness in humans by Whitaker, John, Karády, Júlia, Karim, Rashed, Tobon-Gomez, Catalina, Fastl, Thomas, Razeghi, Orod, O'Neill, Louisa, Decroocq, Marie, Williams, Steven, Corrado, Cesare, Mukherjee, Rahul K., Sim, Iain, O'Hare, Daniel, Kotadia, Irum, Kolossváry, Márton, Merkely, Bela, Littvay, Levente, Tarnoki, Adam D., Tarnoki, David L., Voros, Szilard, Razavi, Reza, O'Neill, Mark, Rajani, Ronak, Maurovich Horvat, Pál, Niederer, Steven

“…Left atrial (LA) remodelling is a common feature of many cardiovascular pathologies and is a sensitive marker of adverse cardiovascular outcomes. The aim of…”
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Left atrial voltage mapping: defining and targeting the atrial fibrillation substrate by Sim, Iain, Bishop, Martin, O’Neill, Mark, Williams, Steven E.

“…Low atrial endocardial bipolar voltage, measured during catheter ablation for atrial fibrillation (AF), is a commonly used surrogate marker for the presence of…”
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Impact of catheter ablation versus medical therapy on cognitive function in atrial fibrillation: a systematic review by Bodagh, Neil, Yap, Reuben, Kotadia, Irum, Sim, Iain, Bhalla, Ajay, Somerville, Peter, O’Neill, Mark, Williams, Steven E.

“…Purpose Atrial fibrillation is associated with an increased risk of cognitive impairment. It is unclear whether the restoration of sinus rhythm with catheter…”
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PO-01-215 ATRIAL FIBRILLATION OUTCOME IS IMPROVED BY BIATRIAL SUBSTRATE ABLATION IN A LARGE VIRTUAL TRIAL by Roney, Caroline H., Solis-Lemus, Jose Alonso, Honarbakhsh, Shohreh, Sim, Iain, Rodero, Cristobal, Strocchi, Marina, Kotadia, Irum, Narayan, Sanjiv M., Plank, Gernot, Vigmond, Edward J., Williams, Steven E., Niederer, Steven A.

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A technique for measuring anisotropy in atrial conduction to estimate conduction velocity and atrial fibre direction by Roney, Caroline H., Whitaker, John, Sim, Iain, O'Neill, Louisa, Mukherjee, Rahul K., Razeghi, Orod, Vigmond, Edward J., Wright, Matthew, O'Neill, Mark D., Williams, Steven E., Niederer, Steven A.

“…Cardiac conduction properties exhibit large variability, and affect patient-specific arrhythmia mechanisms. However, it is challenging to clinically measure…”
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B-PO02-137 OPEN-SOURCE PLATFORM FOR ANALYSIS OF FIBROSIS BEFORE AND AFTER A PULMONARY VEIN ISOLATION PROCEDURE by Solis-Lemus, Jose Alonso, Roney, Caroline H., Razeghi, Orod, Sim, Iain, Kotadia, Irum, Mukherjee, Rahul, Williams, Steven Edwin, O'Neill, Mark, Niederer, Steven A.

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B-PO03-022 INTEGRATING ATRIAL CARDIAC MAGNETIC RESONANCE IMAGING AND ELECTROANATOMIC MAPPING DATA USING UNIVERSAL ATRIAL CO-ORDINATES AND OPENEP (AN OPEN-SOURCE FRAMEWORK FOR ELECTROPHYSIOLOGY RESEARCH) by Williams, Steven Edwin, Roney, Caroline H., Sim, Iain, Kotadia, Irum, Solis-Lemus, Jose Alonso, Razeghi, Orod, Corrado, Cesare, Wright, Matthew James, Niederer, Steven A., O'Neill, Mark D.

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Fully Automatic Atrial Fibrosis Assessment Using a Multilabel Convolutional Neural Network by Razeghi, Orod, Sim, Iain, Roney, Caroline H., Karim, Rashed, Chubb, Henry, Whitaker, John, O’Neill, Louisa, Mukherjee, Rahul, Wright, Matthew, O’Neill, Mark, Williams, Steven E., Niederer, Steven

“…Pathological atrial fibrosis is a major contributor to sustained atrial fibrillation. Currently, late gadolinium enhancement (LGE) scans provide the only…”
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Applications of multimodality imaging for left atrial catheter ablation by Roney, Caroline H, Sillett, Charles, Whitaker, John, Lemus, Jose Alonso Solis, Sim, Iain, Kotadia, Irum, O'Neill, Mark, Williams, Steven E, Niederer, Steven A

“…Abstract Atrial arrhythmias, including atrial fibrillation and atrial flutter, may be treated through catheter ablation. The process of atrial arrhythmia…”
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CA-537-02 MARKED DISCREPANCY IN LEFT ATRIAL LATE GADOLINIUM ENHANCMENT QUANTIFICATION BETWEEN TWO COMMONLY USED TECHNIQUES by Valli, Haseeb, Boyalla, Vennela, Cantor, Emily-Jane, Mohamed Amin Riad, Omar Hatem, Shi, Rui, Sim, Iain, Chen, Zhong, Hussain, Wajid, Jarman, Julian W.E., Jones, David Gareth, Markides, Vias, Mohiaddin, Raad, Wong, Tom, Haldar, Shouvik

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Evaluation of an open-source pipeline to create patient-specific left atrial models: A reproducibility study by Solís-Lemus, José Alonso, Baptiste, Tiffany, Barrows, Rosie, Sillett, Charles, Gharaviri, Ali, Raffaele, Giulia, Razeghi, Orod, Strocchi, Marina, Sim, Iain, Kotadia, Irum, Bodagh, Neil, O’Hare, Daniel, O’Neill, Mark, Williams, Steven E., Roney, Caroline, Niederer, Steven

“…This work presents an open-source software pipeline to create patient-specific left atrial models with fibre orientations and a fibrDEFAULTosis map, suitable…”
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Patient-specific simulations predict efficacy of ablation of interatrial connections for treatment of persistent atrial fibrillation by Roney, Caroline H, Williams, Steven E, Cochet, Hubert, Mukherjee, Rahul K, O'Neill, Louisa, Sim, Iain, Whitaker, John, Razeghi, Orod, Klein, George J, Vigmond, Edward J, O'Neill, Mark, Niederer, Steven A

“…Treatments for persistent atrial fibrillation (AF) offer limited efficacy. One potential strategy aims to return the right atrium (RA) to sinus rhythm (SR) by…”
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