Search Results - "Sim, Hyungtai"
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Comprehensive molecular characterization of TFE3-rearranged renal cell carcinoma
Published in Experimental & molecular medicine (01-08-2024)“…TFE3 -rearranged renal cell cancer (tRCC) is a rare form of RCC that involves chromosomal translocation of the Xp11.2 TFE3 gene. Despite its early onset and…”
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Downregulation of PHGDH expression and hepatic serine level contribute to the development of fatty liver disease
Published in Metabolism, clinical and experimental (01-01-2020)“…Supplementation with serine attenuates alcoholic fatty liver by regulating homocysteine metabolism and lipogenesis. However, little is known about serine…”
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Impact of Evolutionary Changes in Nonalcoholic Fatty Liver Disease on Lung Function Decline
Published in Gut and liver (01-01-2023)“…A relationship between fatty liver and lung function impairment has been identified, and both are independently associated with metabolic dysfunction. However,…”
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Systematic analysis of inheritance pattern determination in genes that cause rare neurodevelopmental diseases
Published in Frontiers in genetics (12-09-2022)“…Despite recent advancements in our understanding of genetic etiology and its molecular and physiological consequences, it is not yet clear what genetic…”
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Disease-specific eQTL screening reveals an anti-fibrotic effect of AGXT2 in non-alcoholic fatty liver disease
Published in Journal of hepatology (01-09-2021)“…Non-alcoholic fatty liver disease (NAFLD) poses an increasing clinical burden. Genome-wide association studies have revealed a limited contribution of genomic…”
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Hepatic upregulation of fetuin-A mediates acetaminophen-induced liver injury through activation of TLR4 in mice
Published in Biochemical pharmacology (01-08-2019)“…[Display omitted] Acetaminophen (APAP)-induced liver injury (AILI) is initiated by the generation of a reactive metabolite and ultimately leads to hepatocyte…”
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Activation of SIRT1 by l-serine increases fatty acid oxidation and reverses insulin resistance in C2C12 myotubes (l-serine activates SIRT1 in C2C12 myotubes)
Published in Cell biology and toxicology (01-10-2019)“…Silent information regulator 1 (SIRT1) is a nicotinamide adenine dinucleotide (NAD + )-dependent deacetylase, and the function is linked to cellular metabolism…”
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Correction to: Activation of SIRT1 by L-serine increases fatty acid oxidation and reverses insulin resistance in C2C12 myotubes
Published in Cell biology and toxicology (01-12-2019)“…The original version of this article unfortunately contained a mistake in the article title…”
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Silencing of fetuin-A protects against acetaminophen-induced hepatotoxicity
Published in Journal of biotechnology (30-08-2017)Get full text
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