Search Results - "Sim, B K"

Live Attenuated Malaria Vaccine Designed to Protect Through Hepatic CD8⁺ T Cell Immunity by Epstein, J. E., Tewari, K., Lyke, K. E., Sim, B. K. L., Billingsley, P. F., Laurens, M. B., Gunasekera, A., Chakravarty, S., James, E. R., Sedegah, M., Richman, A., Velmurugan, S., Reyes, S., Li, M., Tucker, K., Ahumada, A., Ruben, A. J., Li, T., Stafford, R., Eappen, A. G., Tamminga, C., Bennett, J. W., Ockenhouse, C. F., Murphy, J. R., Komisar, J., Thomas, N., Loyevsky, M., Birkett, A., Plowe, C. V., Loucq, C., Edelman, R., Richie, T. L., Seder, R. A., Hoffman, S. L.

“…Our goal is to develop a vaccine that sustainably prevents Plasmodium falciparum (Pf) malaria in ≥80% of recipients. Pf sporozoites (PfSPZ) administered by…”
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Receptor and Ligand Domains for Invasion of Erythrocytes by Plasmodium falciparum by Sim, B. K. L., Chitnis, C. E., Wasniowska, K., Hadley, T. J., Miller, L. H.

“…A 175-kilodalton erythrocyte binding protein, EBA-175, of the parasite Plasmodium falciparum mediates the invasion of erythrocytes. The erythrocyte receptor…”
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Safety and Immunogenicity of a Recombinant Nonglycosylated Erythrocyte Binding Antigen 175 Region II Malaria Vaccine in Healthy Adults Living in an Area Where Malaria Is Not Endemic by El Sahly, H M, Patel, S M, Atmar, R L, Lanford, T A, Dube, T, Thompson, D, Sim, B K L, Long, C, Keitel, W A

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Protection of Aotus Monkeys by Plasmodium falciparum EBA-175 Region II DNA Prime—Protein Boost Immunization Regimen by Jones, Trevor R., Narum, David L., Gozalo, Alfonso S., Aguiar, Joao, Fuhrmann, Steven R., Liang, Hong, Haynes, J. David, Moch, J. Kathleen, Lucas, Carmen, Luu, Tin, Magill, Alan J., Hoffman, Stephen L., Sim, B. K. L.

“…Aotus monkeys received 4 doses of Plasmodium falciparum EBA-175 region II vaccine as plasmid DNA (Dv-Dv) or recombinant protein in adjuvant (Pv-Pv) or as 3…”
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A Nodular Calcification of the Alar Ligament Simulating a Fracture in the Craniovertebral Junction by Sim, K.-B, Park, J.K

“…We report a case of an incidental nodular calcification of the alar ligament simulating a fracture in the craniovertebral junction of a previously healthy…”
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Dose-Dependent Infectivity of Aseptic, Purified, Cryopreserved Plasmodium falciparum 7G8 Sporozoites in Malaria-Naive Adults by Laurens, Matthew B, Berry, Andrea A, Travassos, Mark A, Strauss, Kathy, Adams, Matthew, Shrestha, Biraj, Li, Tao, Eappen, Abraham, Manoj, Anita, Abebe, Yonas, Murshedkar, Tooba, Gunasekera, Anusha, Richie, Thomas L, Lyke, Kirsten E, Plowe, Christopher V, Kennedy, Jessie K, Potter, Gail E, Deye, Gregory A, Sim, B K L, Hoffman, Stephen L

“…Abstract Direct venous inoculation of 3.2 × 103 aseptic, purified, cryopreserved, vialed Plasmodium falciparum (Pf) strain NF54 sporozoites, PfSPZ Challenge…”
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Feasibility of direct venous inoculation of the radiation-attenuated Plasmodium falciparum whole sporozoite vaccine in children and infants in Siaya, western Kenya by Oneko, M., Cherop, Y.R., Sang, T., Gutman, J.R., Wiegand, R., Nyang'au, E.M., Odila, A.D., Akach, D., Hamel, M.J., Samuels, A.M., Kariuki, S., Abebe, Y., Nzuu, E.L., Wijayalath, W., James, E.R., Sim, B.K.L., Billingsley, P.F., Richie, T.L., Hoffman, S.L., Seder, R.A., Steinhardt, L.C.

“…PfSPZ Vaccine, composed of radiation-attenuated, aseptic, purified, cryopreserved Plasmodium falciparum sporozoites, is administered by direct venous…”
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A Family of Erythrocyte Binding Proteins of Malaria Parasites by Adams, John H., B. Kim Lee Sim, Dolan, Stephen A., Fang, Xiangdong, Kaslow, David C., Miller, Louis H.

“…Malaria erythrocyte binding proteins use the Duffy blood group antigen (Plasmodium vivax and Plasmodium knowlesi) and sialic acid (Plasmodium falciparum) on…”
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Identification of an Erythrocyte Binding Peptide from the Erythrocyte Binding Antigen, EBA-175, Which Blocks Parasite Multiplication and Induces Peptide-Blocking Antibodies by JAKOBSEN, P. H, HEEGAARD, P. M. H, KOCH, C, WASNIOWSKA, K, LEMNGE, M. M, JENSEN, J. B, SIM, B. K. L

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Anemia in parasite- and recombinant protein-immunized aotus monkeys infected with Plasmodium falciparum by Jones, Trevor R, Stroncek, David F, Gozalo, Alfonso S, Obaldia, 3rd, Nicanor, Andersen, Ellen M, Lucas, Carmen, Narum, David L, Magill, Alan J, Sim, B K L, Hoffman, Stephen L

“…Plasmodium falciparum-induced anemia was characterized in Aotus monkeys repeatedly immunized by infection with P. falciparum (FVO strain) parasites, then…”
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Expression and potential role of phospholipase D1 in cryoinjured cerebral cortex of rats by Kim, M D, Min, D S, Sim, K B, Cho, H-J, Shin, T

“…The expression and potential role of phospholipase D1 (PLD1) were studied in the cerebral cortex of rats after freeze injury. Histopathologically, cryoinjury,…”
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Maternal persistent vegetative state with successful fetal outcome by Sim, K B

“…A woman suffered from massive blunt injuries in a motor vehicle accident at a presumed 4 weeks' gestation, but she successfully carried the fetus for an…”
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Multiple Forms of Angiostatin Induce Apoptosis in Endothelial Cells by Lucas, R., Holmgren, L., Garcia, I., Jimenez, B., Mandriota, S.J., Borlat, F., Sim, B.K.L., Wu, Z., Grau, G.E., Shing, Y., Soff, G.A., Bouck, N., Pepper, M.S.

“…Angiostatin is a circulating inhibitor of angiogenesis generated by proteolytic cleavage of plasminogen. In this study we have used recombinant human and…”
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Multicentric juvenile pilocytic astrocytoma occurring primarily in the trigone of the lateral ventricle by SIM, K.-B, HONG, S.-K

“…The authors report a juvenile pilocytic astrocytoma (JPA) in the trigone of an 11-year-old girl, apparently with disseminated lesions that disappeared…”
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Temporal expression of osteopontin and CD44 in rat brains with experimental cryolesions by Shin, Taekyun, Ahn, Meejung, Kim, Heechul, Moon, Changjong, Kang, Tae-Young, Lee, Joo-Myoung, Sim, Ki-Bum, Hyun, Jin-Won

“…Expression of osteopontin and CD44 in the brain was studied after cryolesioning to understand how osteopontin and its receptor, CD44, are involved in processes…”
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Temporal patterns of the embryonic intermediate filaments nestin and vimentin expression in the cerebral cortex of adult rats after cryoinjury by Moon, Changjong, Ahn, Meejung, Kim, Seungjoon, Jin, Jae-Kwang, Sim, Ki-Bum, Kim, Hyung-Min, Lee, Mun-Yong, Shin, Taekyun

“…The expression of two embryonic intermediate filaments, nestin and vimentin, in the rat brain at days 0 (control), 1, 4, 7 and 14 post-cryoinjury was studied…”
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Morphological study of surgically induced open neural tube defect in old (14 and 21 days) chick embryos by Sim, Ki-Bum, Cho, Byung-Kyu, Chi, Je G., Wang, Kyu-Chang

“…As an experimental model for the research of open neural tube defect (NTD), the surgical model has several advantages over others, in spite of the fact that…”
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Primary Structure of the 175K Plasmodium falciparum Erythrocyte Binding Antigen and Identification of a Peptide Which Elicits Antibodies That Inhibit Malaria Merozoite Invasion by B. Kim Lee Sim, Orlandi, Palmer A., Haynes, J. David, Klotz, Francis W., Carter, J. Mark, Camus, Daniel, Zegans, Michael E., Chulay, Jeffrey D.

“…The Plasmodium falciparum gene encoding erythrocyte binding antigen-175 (EBA-175), a putative receptor for red cell invasion (Camus, D., and T. J. Hadley…”
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Zinc ligand-disrupted recombinant human endostatin : Potent inhibition of tumor growth, safety and pharmacokinetic profile by SIM, B. K. L, FOGLER, W. E, XIN HUA ZHOU, HONG LIANG, MADSEN, J. W, KIEU LUU, O'REILLY, M. S, TOMASZEWSKI, J. E, FORTIER, A. H

“…Endostatin, a potent endogenous inhibitor of angiogenesis, inhibits the growth of primary tumors without induction of acquired drug resistance in mice. We…”
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Induction of biologically active antibodies in mice, rabbits, and monkeys by Plasmodium falciparum EBA-175 region II DNA vaccine by Sim, B K, Narum, D L, Liang, H, Fuhrmann, S R, Obaldia, 3rd, N, Gramzinski, R, Aguiar, J, Haynes, J D, Moch, J K, Hoffman, S L

“…Plasmodium falciparum merozoites bind to and invade human erythrocytes via specific erythrocyte receptors. This establishes the erythrocytic stage of the…”
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