Search Results - "Silvis, J M"

Short-term effect of low-dose colchicine on inflammatory biomarkers, lipids, blood count and renal function in chronic coronary artery disease and elevated high-sensitivity C-reactive protein by Fiolet, Aernoud T.L, Silvis, Max J.M, Opstal, Tjerk S.J, Bax, Willem A, van der Horst, Frans A.L, Mosterd, Arend, de Kleijn, Dominique, Cornel, Jan H

“…Aims Inflammation plays a pivotal role in atherothrombosis. Colchicine is an anti-inflammatory drug that may attenuate this process. Cardiovascular protective…”
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Extracellular Vesicle cystatin c is associated with unstable angina in troponin negative patients with acute chest pain by Dekker, Mirthe, Waissi, Farahnaz, van Bennekom, Joelle, Silvis, Max J M, Timmerman, Nathalie, Schoneveld, Arjan H, Grobbee, Diederick E, de Winter, Robbert J, Mosterd, Arend, Timmers, Leo, de Kleijn, Dominique P V

“…Despite the use of high-sensitive cardiac troponin there remains a group of high-sensitive cardiac troponin negative patients with unstable angina with a…”
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High levels of osteoprotegerin are associated with coronary artery calcification in patients suspected of a chronic coronary syndrome by Dekker, Mirthe, Waissi, Farahnaz, Silvis, Max J. M., Bennekom, Joelle V., Schoneveld, Arjan H., de Winter, Robbert J., Isgum, Ivana, Lessmann, Nikolas, Velthuis, Birgitta K., Pasterkamp, Gerard, Mosterd, Arend, Timmers, Leo, de Kleijn, Dominique P. V.

“…Plasma osteoprotegerin (OPG) and vascular smooth muscle cell (VSMC) derived extracellular vesicles (EVs) are important regulators in the process of vascular…”
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Plasma extracellular vesicle proteins are associated with stress-induced myocardial ischemia in women presenting with chest pain by Dekker, Mirthe, Waissi, Farahnaz, van Bennekom, Joelle, Silvis, Max J. M., Timmerman, Nathalie, Bank, Ingrid E. M., Walter, Joan E., Mueller, Christian, Schoneveld, A. H., Schiffelers, Raymond M., Pasterkamp, Gerard, Grobbee, Diederick E., de Winter, Robbert J., Mosterd, A., de Kleijn, Dominique P. V., Timmers, Leo

“…Diagnosing stable ischemic heart disease (IHD) is challenging, especially in females. Currently, no blood test is available. Plasma extracellular vesicles (EV)…”
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S/WAVES: The Radio and Plasma Wave Investigation on the STEREO Mission by Bougeret, J. L., Goetz, K., Kaiser, M. L., Bale, S. D., Kellogg, P. J., Maksimovic, M., Monge, N., Monson, S. J., Astier, P. L., Davy, S., Dekkali, M., Hinze, J. J., Manning, R. E., Aguilar-Rodriguez, E., Bonnin, X., Briand, C., Cairns, I. H., Cattell, C. A., Cecconi, B., Eastwood, J., Ergun, R. E., Fainberg, J., Hoang, S., Huttunen, K. E. J., Krucker, S., Lecacheux, A., MacDowall, R. J., Macher, W., Mangeney, A., Meetre, C. A., Moussas, X., Nguyen, Q. N., Oswald, T. H., Pulupa, M., Reiner, M. J., Robinson, P. A., Rucker, H., Salem, C., Santolik, O., Silvis, J. M., Ullrich, R., Zarka, P., Zouganelis, I.

“…This paper introduces and describes the radio and plasma wave investigation on the STEREO Mission: STEREO/WAVES or S/WAVES. The S/WAVES instrument includes a…”
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Targeting residual inflammatory risk in coronary disease: to catch a monkey by its tail by Fiolet, A. T. L., Opstal, T. S. J., Silvis, M. J. M., Cornel, J. H., Mosterd, A.

“…Patients with coronary disease remain at high risk for future cardiovascular events, even with optimal risk factor modification, lipid-lowering drugs and…”
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The Coronary Sinus Reducer; 5-year Dutch experience by Silvis, M. J. M., Dekker, M., Zivelonghi, C., Agostoni, P., Stella, P. R., Doevendans, P. A., de Kleijn, D. P. V., van Kuijk, J. P., Leenders, G. E., Timmers, L.

“…Background Refractory angina is a growing and major health-care problem affecting millions of patients with coronary artery disease worldwide. The Coronary…”
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Experimental parameters and infarct size in closed chest pig LAD ischemia reperfusion models; lessons learned by Silvis, Max J M, van Hout, Gerardus P J, Fiolet, Aernoud T L, Dekker, Mirthe, Bosch, Lena, van Nieuwburg, Martijn M J, Visser, Joyce, Jansen, Marlijn S, Timmers, Leo, de Kleijn, Dominique P V

“…Preclinical models that resemble the clinical setting as closely as possible are essential in translating promising therapies for the treatment of acute…”
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Immunomodulation of the NLRP3 Inflammasome in Atherosclerosis, Coronary Artery Disease, and Acute Myocardial Infarction by Silvis, Max J. M., Demkes, Evelyne J., Fiolet, Aernoud T. L., Dekker, Mirthe, Bosch, Lena, van Hout, Gerardus P. J., Timmers, Leo, de Kleijn, Dominique P. V.

“…Cardiovascular disease (CVD) remains the leading cause of mortality and morbidity worldwide. Atherosclerosis is responsible for the majority of cardiovascular…”
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Damage-Associated Molecular Patterns in Myocardial Infarction and Heart Transplantation: The Road to Translational Success by Silvis, Max J M, Kaffka Genaamd Dengler, Selma E, Odille, Clémence A, Mishra, Mudit, van der Kaaij, Niels P, Doevendans, Pieter A, Sluijter, Joost P G, de Kleijn, Dominique P V, de Jager, Saskia C A, Bosch, Lena, van Hout, Gerardus P J

“…In the setting of myocardial infarction (MI), ischemia reperfusion injury (IRI) occurs due to occlusion (ischemia) and subsequent re-establishment of blood…”
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NLRP3-Inflammasome Inhibition with IZD334 Does Not Reduce Cardiac Damage in a Pig Model of Myocardial Infarction by Silvis, Max J M, Demkes, Evelyne J, Timmers, Leo, Arslan, Fatih, de Jager, Saskia C A, Sluijter, Joost P G, Mosterd, Arend, de Kleijn, Dominique P V, Bosch, Lena, van Hout, Gerardus P J

“…NLRP3-inflammasome-mediated signaling is thought to significantly contribute to the extent of myocardial damage after myocardial infarction (MI). The purpose…”
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Extracellular Vesicles in Diagnosing Chronic Coronary Syndromes the Bumpy Road to Clinical Implementation by Dekker, Mirthe, Waissi, Farahnaz, Timmerman, Nathalie, Silvis, Max J M, Timmers, Leo, de Kleijn, Dominique P V

“…Coronary artery disease (CAD), comprising both acute coronary syndromes (ACS) and chronic coronary syndromes (CCS), remains one of the most important killers…”
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Neutral Effects of Combined Treatment With GLP-1R Agonist Exenatide and MR Antagonist Potassium Canrenoate on Cardiac Function in Porcine and Murine Chronic Heart Failure Models by Demkes, Evelyne J., Wenker, Steven, Silvis, Max J. M., van Nieuwburg, Martijn M. J., Visser, M. Joyce, Jansen, Marlijn S., Brans, Maike A. D., Velema, Evelyn, Sluijter, Joost P. G., Hoefer, Imo E., de Kleijn, Dominique P. V., Timmers, Leo, de Jager, Saskia C. A.

“…Background: Ischemia-reperfusion and cardiac remodeling is associated with cardiomyocyte death, excessive fibrosis formation, and functional decline,…”
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Staphylococcus lugdunensis infective endocarditis with perforation of the sinus of Valsalva: a case report by Silvis, M J M, van den Heuvel, F M A, van Garsse, L, Nijveldt, R

“…Abstract Background Staphylococcus lugdunensis endocarditis is a rare but fulminant disease. Case summary A 74-year-old female with a history of asymptomatic…”
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Colchicine Attenuates Inflammation Beyond the Inflammasome in Chronic Coronary Artery Disease: A LoDoCo2 Proteomic Substudy by Opstal, Tjerk S.J., Hoogeveen, Renate M., Fiolet, Aernoud T.L., Silvis, Max J.M., The, Salem H.K., Bax, Willem A., de Kleijn, Dominique P.V., Mosterd, Arend, Stroes, Erik S.G., Cornel, Jan H.

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Colchicine reduces extracellular vesicle NLRP3 inflammasome protein levels in chronic coronary disease: A LoDoCo2 biomarker substudy by Silvis, Max J.M., Fiolet, Aernoud T.L., Opstal, Tjerk S.J., Dekker, Mirthe, Suquilanda, Daniel, Zivkovic, Minka, Duyvendak, Michiel, The, Salem H.K., Timmers, Leo, Bax, Willem A., Mosterd, Arend, Cornel, Jan H., de Kleijn, Dominique P.V.

“…Colchicine reduces the risk of cardiovascular events in patients with coronary disease. Colchicine has broad anti-inflammatory effects and part of the…”
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Safety and efficacy of coronary sinus narrowing in chronic refractory angina: Insights from the RESOURCE study by Ponticelli, Francesco, Khokhar, Arif A., Leenders, Geert, Konigstein, Maayan, Zivelonghi, Carlo, Agostoni, Pierfrancesco, van Kuijk, Jan-Peter, Ajmi, Issameddine, Lindsay, Steven, Bunc, Matjaž, Tebaldi, Matteo, Cafaro, Alessandro, Cheng, Kevin, Ielasi, Alfonso, Patterson, Tiffany, Wolter, Jan Sebastian, Sgura, Fabio, De Marco, Federico, Ioanes, Dan, D'Amico, Gianpiero, Ciardetti, Marco, Berti, Sergio, Guarracini, Stefano, Di Mauro, Michele, Gallone, Guglielmo, Dekker, Mirthe, Silvis, Max J.M., Tarantini, Giuseppe, Redwood, Simon, Colombo, Antonio, Liebetrau, Christoph, de Silva, Ranil, Rapezzi, Claudio, Ferrari, Roberto, Campo, Gianluca, Schnupp, Steffen, Timmers, Leo, Verheye, Stefan, Stella, Pieter, Banai, Shmuel, Giannini, Francesco

“…Refractory angina (RA) is considered the end-stage of coronary artery disease, and often has no interventional treatment options. Coronary sinus Reducer (CSR)…”
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The Effect of Years-Long Exposure to Low-Dose Colchicine on Renal and Liver Function and Blood Creatine Kinase Levels: Safety Insights from the Low-Dose Colchicine 2 (LoDoCo2) Trial by van Broekhoven, Amber, Mohammadnia, Niekbachsh, Silvis, Max J. M., Los, Jonathan, Fiolet, Aernoud T. L., Opstal, Tjerk S. J., Mosterd, Arend, Eikelboom, John W., Nidorf, Stefan M., Budgeon, Charley A., Byrnes, Elizabeth, Bax, Willem A., Tijssen, Jan G. P., de Kleijn, Dominique P. V., Thompson, Peter L., El Messaoudi, Saloua, Cornel, Jan H.

“…Background and Objective The Low-Dose Colchicine-2 (LoDoCo2) trial showed that 2–4 years exposure to colchicine 0.5 mg once daily reduced the risk of…”
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End-of-trial inflammatory biomarkers, lipid levels, creatine kinase and markers of renal and liver function in the LoDoCo2 trial by Van Broekhoven, A, Mohammadnia, N, Silvis, M J M, Los, J, Fiolet, A T L, Opstal, T S J, Mosterd, A, Eikelboom, J W, Nidorf, S M, Bax, W A, Tijssen, J G P, De Kleijn, D P V, Thompson, P L, El Messaoudi, S, Cornel, J H

“…Abstract Background The Low-Dose Colchicine 2 (LoDoCo2) trial demonstrated that colchicine reduced major cardiovascular events in patients with chronic…”
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Staphylococcus lugdunensis infective endocarditis with perforation of the sinus of Valsalva: a case report by Silvis, M J M, van den Heuvel, F M A, van Garsse, L, Nijveldt, R

“…BackgroundStaphylococcus lugdunensis endocarditis is a rare but fulminant disease. Case summaryA 74-year-old female with a history of asymptomatic severe…”
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