Search Results - "Silvio A. Vasconcellos"

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  1. 1

    Leptospira interrogans Lsa23 protein recruits plasminogen, factor H and C4BP from normal human serum and mediates C3b and C4b degradation by Siqueira, Gabriela H, Atzingen, Marina V, de Souza, Gisele O, Vasconcellos, Silvio A, Nascimento, Ana L T O

    “…It has been reported that pathogenic Leptospira are resistant to normal human serum (NHS) due to their ability to evade the complement immune system by…”
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  2. 2

    OmpL1 Is an Extracellular Matrix- and Plasminogen-Interacting Protein of Leptospira spp by FERNANDES, Luis G. V, VIEIRA, Monica L, KIRCHGATTER, Karin, ALVES, Ivy J, DE MORAIS, Zenaide M, VASCONCELLOS, Silvio A, ROMERO, Eliete C, NASCIMENTO, Ana L. T. O

    Published in Infection and Immunity (01-10-2012)
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  3. 3

    New strategies for Leptospira vaccine development based on LPS removal by Lauretti-Ferreira, Fabiana, Silva, Paloma L D, Alcântara, Naiara M, Silva, Bruna F, Grabher, Isabele, Souza, Gisele O, Nakajima, Erika, Akamatsu, Milena A, Vasconcellos, Silvio A, Abreu, Patricia A E, Carvalho, Eneas, Martins, Elizabeth A L, Ho, Paulo L, da Silva, Josefa B

    Published in PloS one (27-03-2020)
    “…Pathogenic spirochetes from genus Leptospira are etiologic agents of leptospirosis. Cellular vaccines against Leptospira infection often elicit mainly response…”
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  4. 4

    Immunoprotective Activity Induced by Leptospiral Outer Membrane Proteins in Hamster Model of Acute Leptospirosis by Teixeira, Aline F, Cavenague, Maria F, Kochi, Leandro T, Fernandes, Luis G, Souza, Gisele O, de Souza Filho, Antonio Francisco, Vasconcellos, Silvio A, Heinemann, Marcos Bryan, Nascimento, Ana L T O

    Published in Frontiers in immunology (30-10-2020)
    “…Leptospirosis is a zoonotic disease of worldwide distribution, affecting both humans and animals. The development of an effective vaccine against leptospirosis…”
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  5. 5

    Immune response and protective profile elicited by a multi-epitope chimeric protein derived from Leptospira interrogans by Fernandes, Luis G.V, Teixeira, Aline F, Filho, Antonio F.S, Souza, Gisele O, Vasconcellos, Silvio A, Heinemann, Marcos B, Romero, Eliete C, Nascimento, Ana L.T.O

    “…Summary Introduction Pathogenic Leptospira is the causative agent of leptospirosis, a widely disseminated disease of human and veterinary concern. The…”
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  6. 6

    Features of two new proteins with OmpA-like domains identified in the genome sequences of Leptospira interrogans by Teixeira, Aline F, de Morais, Zenaide M, Kirchgatter, Karin, Romero, Eliete C, Vasconcellos, Silvio A, Nascimento, Ana Lucia T O

    Published in PloS one (07-04-2015)
    “…Leptospirosis is an acute febrile disease caused by pathogenic spirochetes of the genus Leptospira. It is considered an important re-emerging infectious…”
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    Adhesins of Leptospira interrogans mediate the interaction to fibrinogen and inhibit fibrin clot formation in vitro by Oliveira, Rosane, Domingos, Renan F, Siqueira, Gabriela H, Fernandes, Luis G, Souza, Natalie M, Vieira, Monica L, de Morais, Zenaide M, Vasconcellos, Silvio A, Nascimento, Ana L T O

    Published in PLoS neglected tropical diseases (01-08-2013)
    “…We report in this work that Leptospira strains, virulent L. interrogans serovar Copenhageni, attenuated L. interrogans serovar Copenhageni and saprophytic L…”
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  9. 9

    Plasminogen Acquisition and Activation at the Surface of Leptospira Species Lead to Fibronectin Degradation by Vieira, Monica L, Vasconcellos, Silvio A, Gonçales, Amane P, de Morais, Zenaide M, Nascimento, Ana L.T.O

    Published in Infection and Immunity (01-09-2009)
    “…Pathogenic Leptospira species are the etiological agents of leptospirosis, a widespread disease of human and veterinary concern. In this study, we report that…”
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  10. 10

    Characterization of three novel adhesins of Leptospira interrogans by Siqueira, Gabriela H, Atzingen, Marina V, Alves, Ivy J, de Morais, Zenaide M, Vasconcellos, Silvio A, Nascimento, Ana L T O

    “…We report cloning, expression, purification, and characterization of three predicted leptospiral membrane proteins (LIC11360, LIC11009, and LIC11975). In…”
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  11. 11

    In vitro identification of novel plasminogen-binding receptors of the pathogen Leptospira interrogans by Vieira, Monica L, Atzingen, Marina V, Oliveira, Tatiane R, Oliveira, Rosane, Andrade, Daniel M, Vasconcellos, Silvio A, Nascimento, Ana L T O

    Published in PloS one (22-06-2010)
    “…Leptospirosis is a multisystem disease caused by pathogenic strains of the genus Leptospira. We have reported that Leptospira are able to bind plasminogen…”
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  12. 12

    Leptospira interrogans reduces fibrin clot formation by modulating human thrombin activity via exosite I by Fernandes, Luis G., de Morais, Zenaide M., Vasconcellos, Silvio A., Nascimento, Ana L. T. O.

    Published in Pathogens and disease (01-06-2015)
    “…Pathogenic bacteria of the genus Leptospira are the etiological agents of leptospirosis, a disease that affects humans and animals worldwide. Although there…”
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  13. 13

    Features of two proteins of Leptospira interrogans with potential role in host-pathogen interactions by Domingos, Renan F, Vieira, Monica L, Romero, Eliete C, Gonçales, Amane Paldes, de Morais, Zenaide M, Vasconcellos, Silvio A, Nascimento, Ana L T O

    Published in BMC microbiology (30-03-2012)
    “…Leptospirosis is considered a re-emerging infectious disease caused by pathogenic spirochaetes of the genus Leptospira. Pathogenic leptospires have the ability…”
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  14. 14

    Interaction of Leptospira interrogans with Human Proteolytic Systems Enhances Dissemination through Endothelial Cells and Protease Levels by Vieira, Monica L, Alvarez-Flores, Miryam P, Kirchgatter, Karin, Romero, Eliete C, Alves, Ivy J, de Morais, Zenaide M, Vasconcellos, Silvio A, Chudzinski-Tavassi, Ana M, Nascimento, Ana L T O

    Published in Infection and Immunity (01-05-2013)
    “…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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  15. 15

    Lsa30, a novel adhesin of Leptospira interrogans binds human plasminogen and the complement regulator C4bp by Souza, Natalie M., Vieira, Monica L., Alves, Ivy J., de Morais, Zenaide M., Vasconcellos, Silvio A., Nascimento, Ana L.T.O.

    Published in Microbial pathogenesis (01-09-2012)
    “…Pathogenic Leptospira is the etiological agent of leptospirosis, a life-threatening disease that affects populations worldwide. Surface proteins have the…”
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    Lsa21, a novel leptospiral protein binding adhesive matrix molecules and present during human infection by Atzingen, Marina V, Barbosa, Angela S, De Brito, Thales, Vasconcellos, Silvio A, de Morais, Zenáide M, Lima, Dirce Mc, Abreu, Patricia Ae, Nascimento, Ana Lto

    Published in BMC microbiology (29-04-2008)
    “…It has been well documented over past decades that interaction of pathogens with the extracellular matrix (ECM) plays a primary role in host cell attachment…”
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    Role of Murine Complement Component C5 in Acute in Vivo Infection by Pathogenic Leptospira interrogans by de Castro, Íris A, Bavia, Lorena, Fraga, Tatiana R, Amano, Mariane T, Breda, Leandro C D, Granados-Martinez, Adriana P, da Silva, Ana M G, Vasconcellos, Silvio A, Isaac, Lourdes

    “…Leptospirosis is considered one of the most important zoonosis worldwide. The activation of the Complement System is important to control dissemination of…”
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  20. 20

    Leptospira interrogans serovar copenhageni harbors two lexA genes involved in SOS response by Fonseca, Luciane S, da Silva, Josefa B, Milanez, Juliana S, Monteiro-Vitorello, Claudia B, Momo, Leonardo, de Morais, Zenaide M, Vasconcellos, Silvio A, Marques, Marilis V, Ho, Paulo L, da Costa, Renata M A

    Published in PloS one (03-10-2013)
    “…Bacteria activate a regulatory network in response to the challenges imposed by DNA damage to genetic material, known as the SOS response. This system is…”
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