Search Results - "Silverstein, Douglas M."

Inflammation in chronic kidney disease: role in the progression of renal and cardiovascular disease by Silverstein, Douglas M.

“…Inflammation is the response of the vasculature or tissues to various stimuli. An acute and chronic pro-inflammatory state exists in patients with chronic…”
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Growth and Nutrition in Pediatric Chronic Kidney Disease by Silverstein, Douglas M

“…Children with chronic kidney disease (CKD) feature significant challenges to the maintenance of adequate nutrition and linear growth. Moreover, the impaired…”
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Presenting Features and Short-Term Outcome According to Pathologic Variant in Childhood Primary Focal Segmental Glomerulosclerosis by Silverstein, Douglas M, Craver, Randall

“…This was a retrospective analysis of children in one center who had primary (idiopathic) FSGS. There were 41 patients: 34.1% female, 65.9% male, 80.5% black,…”
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High incidence of initial and late steroid resistance in childhood nephrotic syndrome by Kim, Jung Sue, Bellew, Christine A., Silverstein, Douglas M., Aviles, Diego H., Boineau, Frank G., Vehaskari, V. Matti

“…High incidence of initial and late steroid resistance in childhood nephrotic syndrome. Conventional wisdom states that greater than 80% of children with…”
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Pro- and Anti-Inflammatory Cytokines in Chronic Pediatric Dialysis Patients: Effect of Aspirin by Goldstein, Stuart L, Leung, Jocelyn C, Silverstein, Douglas M

“…Dialysis provides effective and safe treatment of ESRD in children, but patients who are maintained on chronic dialysis are at risk for cardiovascular disease…”
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Renal development: a complex process dependent on inductive interaction by Upadhyay, Kiran K, Silverstein, Douglas M

“…Renal development begins in-utero and continues throughout childhood. Almost one-third of all developmental anomalies include structural or functional…”
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Cinacalcet is efficacious in pediatric dialysis patients by Silverstein, Douglas M., Kher, Kanwal K., Moudgil, Asha, Khurana, Mona, Wilcox, Jennifer, Moylan, Kathleen

“…Secondary hyperparathyroidism (high-turnover bone disease, or HTBD) is manifested by elevated parathyroid hormone (PTH) levels. Control of HTBD may be achieved…”
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Frequent hemodialysis: history of the modality and assessment of outcomes by Silverstein, Douglas M.

“…About 660,000 individuals have end-stage renal disease in the USA, the vast majority of whom are receiving standard, in-center, thrice-weekly hemodialysis…”
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Etiology and management of dyslipidemia in children with chronic kidney disease and end-stage renal disease by Khurana, Mona, Silverstein, Douglas M.

“…Lipids are essential components of cell membranes, contributing to cell fuel, myelin formation, subcellular organelle function, and steroid hormone synthesis…”
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Effect of age, ethnicity, and glucocorticoid use on tacrolimus pharmacokinetics in pediatric renal transplant patients by Kim, Jung Sue, Aviles, Diego H., Silverstein, Douglas M., LeBlanc, Pamela L., Matti Vehaskari, V.

“…:  Tacrolimus has become an effective alternative to cyclosporine as a component of primary immunosuppression in pediatric renal transplant patients, but the…”
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Regulatory Considerations for Hemodiafiltration in the United States by Ward, Richard A, Vienken, Jörg, Silverstein, Douglas M, Ash, Stephen, Canaud, Bernard

“…Online hemodiafiltration provides greater removal of higher molecular weight uremic retention solutes than conventional high-flux hemodialysis. However, online…”
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Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction by Silverstein, Douglas M., Travis, Brett R., Thornhill, Barbara A., Schurr, Jill S., Kolls, Jay K., Leung, Jocelyn C., Chevalier, Robert L.

“…Altered expression of immune modulator and structural genes in neonatal unilateral ureteral obstruction. Congenital obstructive nephropathy is a condition…”
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Clinical and Regulatory Considerations for Central Venous Catheters for Hemodialysis by Silverstein, Douglas M, Trerotola, Scott O, Clark, Timothy, James, Garth, Ng, Wing, Dwyer, Amy, Florescu, Marius C, Shingarev, Roman, Ash, Stephen R

“…Central venous catheters remain a vital option for access for patients receiving maintenance hemodialysis. There are many important and evolving clinical and…”
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Expression and developmental regulation of the NMDA receptor subunits in the kidney and cardiovascular system by Leung, Jocelyn C, Travis, Brett R, Verlander, Jill W, Sandhu, Satinder K, Yang, Song-Gui, Zea, Arnold H, Weiner, I David, Silverstein, Douglas M

“…Antagonists to the N-methyl-D-aspartate (NMDA) receptor bind to various extraneuronal tissues. We therefore assessed the expression of the main NMDA subunit,…”
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Barriers to medication adherence and its relationship with outcomes in pediatric dialysis patients by Silverstein, Douglas M., Fletcher, Angela, Moylan, Kathleen

“…Background Medication adherence is a major factor determining outcome in children with chronic disease. Children with end-stage renal disease are challenged…”
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Elevated FGF 23 and phosphorus are associated with coronary calcification in hemodialysis patients by Srivaths, Poyyapakkam R., Goldstein, Stuart L., Silverstein, Douglas M., Krishnamurthy, Rajesh, Brewer, Eileen D.

“…Increased mortality of adult chronic hemodialysis (HD) patients is associated with coronary calcifications (CC), increased serum phosphorus (P), use of calcium…”
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FDA Regulatory Perspectives for Studies on Hemodialysis Vascular Access by Hurst, Frank P, Lee, Robert E, Thompson, Aliza M, Pullin, Brian D, Silverstein, Douglas M

“…In an effort to foster innovation and new product development, the American Society of Nephrology and the US Food and Drug Administration partnered to form the…”
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Non-infected hemodialysis catheters are associated with increased inflammation compared to arteriovenous fistulas by Goldstein, Stuart L., Ikizler, T. Alp, Zappitelli, Michael, Silverstein, Douglas M., Ayus, Juan C.

“…Although hemodialysis catheters predispose to infection which, in turn, causes inflammation, we studied whether they induce inflammation independent of…”
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Management of anemia with erythropoietic-stimulating agents in children with chronic kidney disease by Warady, Bradley A., Silverstein, Douglas M.

“…Anemia management is an important component of the care provided to children with chronic kidney disease (CKD) and influences both morbidity and mortality…”
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High serum phosphorus and FGF 23 levels are associated with progression of coronary calcifications by Srivaths, Poyyapakkam R., Goldstein, Stuart L., Krishnamurthy, Rajesh, Silverstein, Douglas M.

“…Background Coronary calcifications (CC) portend increased mortality in adults receiving hemodialysis (HD), however the risk factors associated with CC…”
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