Search Results - "Silverman, M. A."

Eliciting the impacts of cellular noise on metabolic trade-offs by quantitative mass imaging by Vasdekis, A. E., Alanazi, H., Silverman, A. M., Williams, C. J., Canul, A. J., Cliff, J. B., Dohnalkova, A. C., Stephanopoulos, G.

“…Optimal metabolic trade-offs between growth and productivity are key constraints in strain optimization by metabolic engineering; however, how cellular noise…”
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KIF1A is the primary anterograde motor protein required for the axonal transport of dense-core vesicles in cultured hippocampal neurons by Lo, K.Y., Kuzmin, A., Unger, S.M., Petersen, J.D., Silverman, M.A.

“…► Dense core vesicles and KIF1A co-transport in a bidirectional manner in axons. ► Knockdown of KIF1A reduces bidirectional axonal transport of dense-core…”
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Dynactin regulates bidirectional transport of dense-core vesicles in the axon and dendrites of cultured hippocampal neurons by Kwinter, D.M, Lo, K, Mafi, P, Silverman, M.A

“…Abstract A critical aspect of nerve cell function is peptidergic secretion involving the packaging, transport, and processing of a large group of peptide…”
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Sorting and Directed Transport of Membrane Proteins during Development of Hippocampal Neurons in Culture by Silverman, M. A., Kaech, S., Jareb, M., Burack, M. A., Vogt, L., Sonderegger, P., Banker, G.

“…Hippocampal neurons in culture develop morphological polarity in a sequential pattern; axons form before dendrites. Molecular differences, particularly those…”
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Susceptibility genes for nicotine dependence : a genome scan and followup in an independent sample suggest that regions on chromosomes 2, 4, 10, 16, 17 and 18 merit further study by STRAUB, R. E, SULLIVAN, P. F, NEALE, M. C, BULIK, C. M, JOYCE, P. R, KENDLER, K. S, MA, Y, MYAKISHEV, M. V, HARRIS-KERR, C, WORMLEY, B, KADAMBI, B, SADEK, H, SILVERMAN, M. A, WEBB, B. T

“…Cigarette smoking is associated with considerable morbidity, mortality, and public health costs. Genetic factors influence both smoking initiation and nicotine…”
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Origins of Cell-to-Cell Bioprocessing Diversity and Implications of the Extracellular Environment Revealed at the Single-Cell Level by Vasdekis, A. E., Silverman, A. M., Stephanopoulos, G.

“…Bioprocess limitations imposed by microbial cell-to-cell phenotypic diversity remain poorly understood. To address this, we investigated the origins of such…”
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Inappropriate Medication Prescribing in Homebound Older Adults by Golden, Adam G., Preston, Richard A., Barnett, Scott D., Llorente, Maria, Hamdan, Kamal, Silverman, Michael A.

“…OBJECTIVES Little is known about the prescribing of medications in the growing population of homebound older adults. We report on the prevalence and pattern of…”
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Axonal Transport of Lysosomes Is Unaffected in Glucocerebrosidase-Inhibited iPSC-Derived Forebrain Neurons by Keefe, A. J., Gabrych, D. R., Zhu, Y., Vocadlo, D. J., Silverman, M. A.

“…Lysosomes are acidic organelles that traffic throughout neurons delivering catabolic enzymes to distal regions of the cell and maintaining degradative demands…”
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Motifs that mediate dendritic targeting in hippocampal neurons: A comparison with basolateral targeting signals by Silverman, M.A., Peck, R., Glover, G., He, C., Carlin, C., Banker, G.

“…One model for dendritic protein sorting in neurons is based on parallels with basolateral targeting in Madin–Darby Canine Kidney (MDCK) epithelial cells. The…”
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GSK3β Impairs KIF1A Transport in a Cellular Model of Alzheimer's Disease but Does Not Regulate Motor Motility at S402 by Gan, K J, Akram, A, Blasius, T L, Ramser, E M, Budaitis, B G, Gabrych, D R, Verhey, K J, Silverman, M A

“…Impairment of axonal transport is an early pathologic event that precedes neurotoxicity in Alzheimer's disease (AD). Soluble amyloid-β oligomers (AβOs), a…”
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Expression of kinesin superfamily genes in cultured hippocampal neurons by Silverman, M. A., Kaech, S., Ramser, E. M., Lu, X., Lasarev, M. R., Nagalla, S., Banker, G.

“…The nature of the different kinesin family members that function in a single, specific neuron type has not been systematically investigated. Here, we used…”
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Use of Antipsychotic Drugs in Nursing Homes: Current Compliance with OBRA Regulations by Llorente, Maria D., Olsen, Edwin J., Leyva, Oscar, Silverman, Michael A., Lewis, John E., Rivero, Jesus

“…OBJECTIVE: To examine the degree and patterns of compliance with the Omnibus Budget Reconciliation Act (OBRA) regulations regarding the use of antipsychotic…”
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Characterization of Caenorhabditis elegans Lectin-Binding Mutants by Link, C. D, Silverman, M. A, Breen, M, Watt, K. E, Dames, S. A

“…We have identified 45 mutants of Caenorhabditis elegans that show ectopic surface binding of the lectins wheat germ agglutinin (WGA) and soybean agglutinin…”
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The Role of Selective Transport in Neuronal Protein Sorting by Burack, Michelle A., Silverman, Michael A., Banker, Gary

“…To assess whether selective microtubule-based vesicle transport underlies the polarized distribution of neuronal proteins, we expressed green fluorescent…”
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Regulation of Peptidergic Vesicle Mobility by Secretagogues by Washburn, C. L., Bean, J. E., Silverman, M. A., Pellegrino, M. J., Yates, P. A., Allen, R. G.

“…Neuropeptides are released into the extracellular space from large secretory granules. In order to reach their release sites, these granules are translocated…”
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Erratum: Intracellular amyloid β oligomers impair organelle transport and induce dendritic spine loss in primary neurons by Umeda, T, Ramser, E M, Yamashita, M, Nakajima, K, Mori, H, Silverman, M A, Tomiyama, T

“…The original version of this article unfortunately contained a mistake in the presentation of Fig. 1 in both the PDF and HTML versions of this manuscript [1]…”
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MOOD AND BEHAVIOUR PROBLEMS FOLLOWING THE RELOCATION OF ELDERLY PATIENTS WITH MENTAL ILLNESS by ANTHONY, KIM, PROCTER, ANDREW W., SILVERMAN, A. M., MURPHY, ELAINE

“…A prospective case-controlled study was carried out to evaluate the effect of an enforced move of elderly dementia sufferers from a large psychiatric hospital…”
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Medical readiness training exercise in El Salvador, Central America, 1996 by SILVERMAN, M. A, BARNES, D, ZLAMAL, R, SOUTHWORTH, S, MCKINNEY, R, LAUBACH, H, DILEO, I. D, BERGER, M

“…Medical Readiness Training Exercises (MEDRETEs) can be a valuable training tool for U.S. Army personnel in remote areas of deployment. We report our experience…”
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A case presentation of Sweet's syndrome and discussion of life-threatening dermatoses by Silverman, Michael A, Datner, Elizabeth M, Jolly, B.Tilman

“…Sweet first described acute febrile neutrophilic dermatosis in 1964. Since then, more than 425 cases of this typically benign, steroid-responsive disease have…”
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Cholecystokinin receptor antagonists: a review by Silverman, M A, Greenberg, R E, Bank, S

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