Search Results - "Silverman, Lawrence A"

A review of the genetics and epigenetics of central precocious puberty by Moise-Silverman, Joshua, Silverman, Lawrence A

“…Gonadotrophin dependent sexual precocity, commonly referred to as central precocious puberty (CPP), results from a premature reactivation of the…”
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Gonadotropin-releasing hormone analog therapies for children with central precocious puberty in the United States by Popovic, Jadranka, Geffner, Mitchell E., Rogol, Alan D., Silverman, Lawrence A., Kaplowitz, Paul B., Mauras, Nelly, Zeitler, Philip, Eugster, Erica A., Klein, Karen O.

“…Gonadotropin-releasing hormone agonists (GnRHa's) are the standard treatment for children with central precocious puberty (CPP). We aim to present data on…”
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Comparing the efficacy and safety of weekly somatrogon with daily somatropin to treat children with growth hormone deficiency: a plain language summary of publication by Deal, Cheri L., Steelman, Joel, Vlachopapadopoulou, Elpis, Stawerska, Renata, Silverman, Lawrence A., Phillip, Moshe, Kim, Ho-Seong, Ko, CheolWoo, Malievskiy, Oleg, Cara, Jose F., Roland, Carl L., Taylor, Carrie Turich, Valluri, Srinivas Rao, Wajnrajch, Michael P., Pastrak, Aleksandra, Miller, Bradley S.

“…• The efficacy of weekly somatrogon injections was no different from that of daily somatropin injections to treat children who don’t make enough growth hormone…”
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Diagnosis of Central Precocious Puberty by Bangalore Krishna, Kanthi, Silverman, Lawrence A.

“…A thorough history and physical examination including Tanner staging and growth assessments can guide differential diagnosis and aid in the evaluation of…”
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Veganism as a cause of iodine deficient hypothyroidism by Yeliosof, Olga, Silverman, Lawrence A

“…Iodine deficiency is the most common cause of acquired hypothyroidism worldwide. Although uncommon in the Western world, the incidence of iodine deficiency may…”
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Efficacy and Safety of Weekly Somatrogon vs Daily Somatropin in Children With Growth Hormone Deficiency: A Phase 3 Study by Deal, Cheri L, Steelman, Joel, Vlachopapadopoulou, Elpis, Stawerska, Renata, Silverman, Lawrence A, Phillip, Moshe, Kim, Ho-Seong, Ko, CheolWoo, Malievskiy, Oleg, Cara, Jose F, Roland, Carl L, Taylor, Carrie Turich, Valluri, Srinivas Rao, Wajnrajch, Michael P, Pastrak, Aleksandra, Miller, Bradley S

“…Somatrogon is a long-acting recombinant human growth hormone (rhGH) in development for once-weekly treatment of children with growth hormone deficiency (GHD)…”
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Ease of use and preference for a new disposable self-injection pen compared with a reusable pen for administering recombinant human growth hormone: A multicenter, 2-Month, single-arm, open-label clinical trial in patient-caregiver dyads by Hey-Hadavi, Judith, MD, Pleil, Andreas, PhD, Deeb, Larry C., MD, Fuqua, John S., MD, Silverman, Lawrence A., MD, Reiner, Barry, MD, Newfield, Ron, MD, Rajicic, Natasa, ScD, Wajnrajch, Michael P., MD, Cara, Jose F., MD

“…Abstract Background: Improved ease of use of drug-delivery devices may enhance compliance. Development of an easier-to-use device for administration of…”
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Long-Term Continuous Suppression With Once-Yearly Histrelin Subcutaneous Implants for the Treatment of Central Precocious Puberty: A Final Report of a Phase 3 Multicenter Trial by Silverman, Lawrence A, Neely, E. Kirk, Kletter, Gad B, Lewis, Katherine, Chitra, Surya, Terleckyj, Oksana, Eugster, Erica A

“…Context and Objective: The histrelin implant has proven to be an effective method of delivering GnRH analog (GnRHa) therapy to children with central precocious…”
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Clinical characteristics and treatment patterns with histrelin acetate subcutaneous implants vs. leuprolide injections in children with precocious puberty: a real-world study using a US claims database by Silverman, Lawrence A, Han, Xu, Huang, Huan, Near, Aimee M, Hu, Yiqun

“…Gonadotropin-releasing hormone analogs are the treatment of choice for central precocious puberty (CPP). This study characterizes patients treated with…”
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Suboptimal adherence to prescribed daily growth hormone regimen among medicaid beneficiaries in the United States by Loftus, Jane, Chen, Yong, Gupta, Anu, Wajnrajch, Michael P., Alvir, Jose Ma. J., Silverman, Lawrence A., Jhingran, Priti, Kumar, Mahesh, Prasad, Sapna

“…The objective of this retrospective cohort study was to describe the adherence and discontinuation patterns of somatropin over 3 years among children with pGHD…”
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Y chromosome gene copy number and lack of autism phenotype in a male with an isodicentric Y chromosome and absent NLGN4Y expression by Ross, Judith L., Bloy, Luke, Roberts, Timothy P. L., Miller, Judith, Xing, Chao, Silverman, Lawrence A., Zinn, Andrew R.

“…We describe a unique male with a dicentric Y chromosome whose phenotype was compared to that of males with 47,XYY (XYY). The male Y‐chromosome aneuploidy XYY…”
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Review of outcomes after cessation of gonadotropin-releasing hormone agonist treatment of girls with precocious puberty by Thornton, Paul, Silverman, Lawrence A, Geffner, Mitchell E, Neely, E Kirk, Gould, Errol, Danoff, Theodore M

“…Although gonadotropin-releasing hormone agonists (GnRHa) have been the standard of care of central precocious puberty (CPP) management for many years, there…”
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A 4-Year, Open-Label, Multicenter, Randomized Trial of Genotropin® Growth Hormone in Patients with Idiopathic Short Stature: Analysis of 4-Year Data Comparing Efficacy, Efficiency, and Safety between an Individualized, Target-Driven Regimen and Standard Dosing by Counts, Debra R, Silverman, Lawrence A, Rajicic, Natasa, Geffner, Mitchell E, Newfield, Ron S, Thornton, Paul, Carakushansky, Mauri, Escobar, Oscar, Rapaport, Robert, Levitsky, Lynne, Rotenstein, Deborah, Hey-Hadavi, Judith, Wajnrajch, Michael P

“…Growth hormone (GH) treatment regimens for children with non-GH-deficient, idiopathic short stature (ISS) have not been optimized. To compare the efficacy,…”
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9. Two and a half years of clinical experience with six month subcutaneous leuprolide acetate treatment for pubertal suppression in three boys by Sabanosh, Kristin, Atkinson, Stuart N., Boldt-Houle, Deborah M., Daugherty, Rhea, O'Brien, Mark, Silverman, Lawrence A.

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THU004 Impact Of Continuous Medical Education At Improving Knowledge And Confidence Related To New And Emerging Pediatric Growth Hormone Deficiency Treatment Options by Larkin, Amy, Capparelli, Catherine, Miller, Bradley Scott, Geffner, Mitchell E, Silverman, Lawrence A

“…Abstract Disclosure: A. Larkin: None. C. Capparelli: None. B.S. Miller: Advisory Board Member; Self; Abbvie, Vertice, Ascendis, Bristol-Myers Squibb, Biomarin,…”
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Suboptimal adherence to prescribed daily growth hormone regimen among medicaid beneficiaries in the United States by Loftus, Jane, Chen, Yong, Gupta, Anu, Wajnrajch, Michael P, Alvir, Jose Ma J, Silverman, Lawrence A, Jhingran, Priti, Kumar, Mahesh, Prasad, Sapna

“…The objective of this retrospective cohort study was to describe the adherence and discontinuation patterns of somatropin over 3 years among children with pGHD…”
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OR10-06 Somatrogon Growth Hormone in the Treatment of Pediatric Growth Hormone Deficiency: Results of the Pivotal Pediatric Phase 3 Clinical Trial by Deal, Cheri L, Pastrak, Aleksandra, Silverman, Lawrence A, Valluri, Srinivas Rao, Wajnrajch, Michael Paul, Cara, Jose Francisco

“…Abstract Background: Somatrogon (hGH-CTP) is a long acting recombinant human growth hormone (rhGH; somatropin) in development for once weekly treatment of…”
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Switch Data From the Open-Label Extension of the Pivotal Phase 3 Study of Once Weekly Somatrogon Compared to Daily Somatropin in Pediatric Patients With Growth Hormone Deficiency (pGHD) by Wajnrajch, Michael, Miller, Bradley Scott, Steelman, Joel, Silverman, Lawrence A, Phillip, Moshe, Vlachopapadopoulou, Elpis, Stawerska, Renata, Kim, Ho-Seong, Malievskiy, Oleg, Ko, Cheol Woo, Valluri, Srinivas Rao, Taylor, Carrie Turich, Roland, Carl L, Choe, John, Pastrak, Aleksandra, Deal, Cheri L

“…Abstract Objectives: Somatrogon (hGH-CTP) is a long acting recombinant human growth hormone, consisting of the amino acid sequence of hGH and three copies of…”
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Continuous Hormone Suppression and Improved Auxology Outcomes in Children With Central Precocious Puberty Who Received a Once-Yearly Histrelin Subcutaneous Implant for 4 Consecutive Years by Silverman, Lawrence A., Kletter, Gad B., Neely, E. Kirk, Chita, Surya, Chan, Arthur

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Random unstimulated pediatric luteinizing hormone levels are not reliable in the assessment of pubertal suppression during histrelin implant therapy by Neely, E Kirk, Silverman, Lawrence A, Geffner, Mitchell E, Danoff, Theodore M, Gould, Errol, Thornton, Paul S

“…Gonadotropin-releasing hormone agonist (GnRHa)-stimulated luteinizing hormone (LH) is the standard hormonal assessment for both diagnosis and therapeutic…”
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