Search Results - "Silverman, Bernard"

Multiple‐systems analysis for the quantification of modern slavery: classical and Bayesian approaches by Silverman, Bernard W.

“…Summary Multiple‐systems estimation is a key approach for quantifying hidden populations such as the number of victims of modern slavery. The UK Government…”
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Multiple Systems Estimation for Sparse Capture Data: Inferential Challenges When There Are Nonoverlapping Lists by Chan, Lax, Silverman, Bernard W., Vincent, Kyle

“…Multiple systems estimation strategies have recently been applied to quantify hard-to-reach populations, particularly when estimating the number of victims of…”
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Injectable extended-release naltrexone for opioid dependence: a double-blind, placebo-controlled, multicentre randomised trial by Krupitsky, Evgeny, Prof, Nunes, Edward V, Prof, Ling, Walter, Prof, Illeperuma, Ari, MA, Gastfriend, David R, MD, Silverman, Bernard L, MD

“…Summary Background Opioid dependence is associated with low rates of treatment-seeking, poor adherence to treatment, frequent relapse, and major societal…”
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Efficacy and Safety of a Combination of Olanzapine and Samidorphan in Adult Patients With an Acute Exacerbation of Schizophrenia: Outcomes From the Randomized, Phase 3 ENLIGHTEN-1 Study by Potkin, Steven G, Kunovac, Jelena, Silverman, Bernard L, Simmons, Adam, Jiang, Ying, DiPetrillo, Lauren, McDonnell, David

“…To assess the antipsychotic efficacy and safety of a combination of olanzapine and samidorphan (OLZ/SAM). This 4-week, phase 3, randomized, double-blind,…”
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Mitigation of Olanzapine-Induced Weight Gain With Samidorphan, an Opioid Antagonist: A Randomized Double-Blind Phase 2 Study in Patients With Schizophrenia by Martin, William F, Correll, Christoph U, Weiden, Peter J, Jiang, Ying, Pathak, Sanjeev, DiPetrillo, Lauren, Silverman, Bernard L, Ehrich, Elliot W

“…Objective:Preclinical evidence and data from a proof-of-concept study in healthy volunteers suggest that samidorphan, an opioid antagonist, mitigates weight…”
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Bootstrapping multiple systems estimates to account for model selection by Silverman, Bernard W., Chan, Lax, Vincent, Kyle

“…Multiple systems estimation using a Poisson loglinear model is a standard approach to quantifying hidden populations where data sources are based on lists of…”
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A randomized, double-blind, placebo-controlled trial of aripiprazole lauroxil in acute exacerbation of schizophrenia by Meltzer, Herbert Y, Risinger, Robert, Nasrallah, Henry A, Du, Yangchun, Zummo, Jacqueline, Corey, Lisa, Bose, Anjana, Stankovic, Srdjan, Silverman, Bernard L, Ehrich, Elliot W

“…This study evaluated the efficacy, safety, and tolerability of aripiprazole lauroxil, a novel long-acting injectable atypical antipsychotic, for the treatment…”
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A randomized, double-blind, placebo-controlled proof of concept study to evaluate samidorphan in the prevention of olanzapine-induced weight gain in healthy volunteers by Silverman, Bernard L., Martin, William, Memisoglu, Asli, DiPetrillo, Lauren, Correll, Christoph U., Kane, John M.

“…Antipsychotic medications are associated with weight gain and adverse metabolic effects that complicate the treatment and management of schizophrenia…”
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A phase 3, multicenter study to assess the 1-year safety and tolerability of a combination of olanzapine and samidorphan in patients with schizophrenia: Results from the ENLIGHTEN-2 long-term extension by Kahn, René S., Silverman, Bernard L., DiPetrillo, Lauren, Graham, Christine, Jiang, Ying, Yin, Jiani, Simmons, Adam, Bhupathi, Vasudev, Yu, Bei, Yagoda, Sergey, Hopkinson, Craig, McDonnell, David

“…A combination of olanzapine and samidorphan (OLZ/SAM) is in development for the treatment of patients with schizophrenia or bipolar I disorder and is intended…”
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Covid-19 and child criminal exploitation in the UK: implications of the pandemic for county lines by Brewster, Ben, Robinson, Grace, Silverman, Bernard W., Walsh, Dave

“…In March 2020, the UK was placed in lockdown following the spread of the Covid-19 virus. Just as legitimate workplaces made changes to enable their employees…”
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Globalization and Modern Slavery by Landman, Todd, Silverman, Bernard W.

“…This article presents a cross-national comparative analysis of the relationship between different dimensions of globalization and modern slavery. It argues…”
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Injectable extended-release naltrexone (XR-NTX) for opioid dependence: long-term safety and effectiveness by Krupitsky, Evgeny, Nunes, Edward V., Ling, Walter, Gastfriend, David R., Memisoglu, Asli, Silverman, Bernard L.

“…Aims To describe drug use and safety with intramuscular injectable extended‐release naltrexone (XR‐NTX) in opioid dependence during a 1‐year open‐label…”
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The contribution of species richness and composition to bacterial services by Lilley, Andrew K, Bell, Thomas, Newman, Jonathan A, Silverman, Bernard W, Turner, Sarah L

“…Bacterial communities provide important services. They break down pollutants, municipal waste and ingested food, and they are the primary means by which…”
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Effect of patient age on treatment response in a study of the acute exacerbation of psychosis in schizophrenia by Targum, Steven D, Risinger, Robert, Du, Yangchun, Pendergrass, J. Cara, Jamal, Hassan H, Silverman, Bernard. L

“…Abstract Younger patients with schizophrenia have most likely experienced fewer adverse consequences of the illness than older patients who may have…”
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Key questions for modelling COVID-19 exit strategies by Thompson, Robin N, Hollingsworth, T Déirdre, Isham, Valerie, Arribas-Bel, Daniel, Ashby, Ben, Britton, Tom, Challenor, Peter, Chappell, Lauren H K, Clapham, Hannah, Cunniffe, Nik J, Dawid, A Philip, Donnelly, Christl A, Eggo, Rosalind M, Funk, Sebastian, Gilbert, Nigel, Glendinning, Paul, Gog, Julia R, Hart, William S, Heesterbeek, Hans, House, Thomas, Keeling, Matt, Kiss, István Z, Kretzschmar, Mirjam E, Lloyd, Alun L, McBryde, Emma S, McCaw, James M, McKinley, Trevelyan J, Miller, Joel C, Morris, Martina, O'Neill, Philip D, Parag, Kris V, Pearson, Carl A B, Pellis, Lorenzo, Pulliam, Juliet R C, Ross, Joshua V, Tomba, Gianpaolo Scalia, Silverman, Bernard W, Struchiner, Claudio J, Tildesley, Michael J, Trapman, Pieter, Webb, Cerian R, Mollison, Denis, Restif, Olivier

“…Combinations of intense non-pharmaceutical interventions (lockdowns) were introduced worldwide to reduce SARS-CoV-2 transmission. Many governments have begun…”
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Needles and Straw in Haystacks: Empirical Bayes Estimates of Possibly Sparse Sequences by Johnstone, Iain M., Silverman, Bernard W.

“…An empirical Bayes approach to the estimation of possibly sparse sequences observed in Gaussian white noise is set out and investigated. The prior considered…”
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Opioid use and dropout from extended‐release naltrexone in a controlled trial: implications for mechanism by Nunes, Edward V., Bisaga, Adam, Krupitsky, Evgeny, Nangia, Narinder, Silverman, Bernard L., Akerman, Sarah C., Sullivan, Maria A.

“…Background and aims Extended‐release formulations of naltrexone have emerged as effective treatment options for opioid use disorder. This post‐hoc analysis…”
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Effects of the Opioid System Modulator, Samidorphan, on Measures of Alcohol Consumption and Patient‐Reported Outcomes in Adults with Alcohol Dependence by O'Malley, Stephanie S., Todtenkopf, Mark S., Du, Yangchun, Ehrich, Elliot, Silverman, Bernard L.

“…Background Demonstrating clinically meaningful benefits of alcohol use disorder treatments is challenging. Methods We report findings from a 12‐week, phase 2,…”
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Insulin and glucose metabolism with olanzapine and a combination of olanzapine and samidorphan: exploratory phase 1 results in healthy volunteers by Toledo, Frederico G S, Martin, William F, Morrow, Linda, Beysen, Carine, Bajorunas, Daiva, Jiang, Ying, Silverman, Bernard L, McDonnell, David, Namchuk, Mark N, Newcomer, John W, Graham, Christine

“…A combination of olanzapine and samidorphan (OLZ/SAM) received US Food and Drug Administration approval in May 2021 for the treatment of adults with…”
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Empirical Bayes Selection of Wavelet Thresholds by Johnstone, Iain M., Silverman, Bernard W.

“…This paper explores a class of empirical Bayes methods for level-dependent threshold selection in wavelet shrinkage. The prior considered for each wavelet…”
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