Search Results - "Silver, Wayne L"

Nasal Chemosensory Cells Use Bitter Taste Signaling to Detect Irritants and Bacterial Signals by Tizzano, Marco, Gulbransen, Brian D., Vandenbeuch, Aurelie, Clapp, Tod R., Herman, Jake P., Sibhatu, Hiruy M., Churchill, Mair E. A., Silver, Wayne L., Kinnamon, Sue C., Finger, Thomas E., Hildebrand, John G.

“…The upper respiratory tract is continually assaulted with harmful dusts and xenobiotics carried on the incoming airstream. Detection of such irritants by the…”
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A TRPA1-dependent mechanism for the pungent sensation of weak acids by Wang, Yuanyuan Y, Chang, Rui B, Allgood, Sallie D, Silver, Wayne L, Liman, Emily R

“…Acetic acid produces an irritating sensation that can be attributed to activation of nociceptors within the trigeminal ganglion that innervate the nasal or…”
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Solitary Chemoreceptor Cells in the Nasal Cavity Serve as Sentinels of Respiration by Finger, Thomas E., Böttger, Bärbel, Hansen, Anne, Anderson, Karl T., Alimohammadi, Hessamedin, Silver, Wayne L.

“…Inhalation of irritating substances leads to activation of the trigeminal nerve, triggering protective reflexes that include apnea or sneezing. Receptors for…”
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Dendrobaena veneta avoids ethyl pentanoate and ethyl hexanoate, two compounds produced by the soil fungus Geotrichum candidum by Reed, Eileen M.S, O'Connor, Mariel O, Johnson, Ione C, Silver, Wayne L, Saunders, Cecil J

“…Earthworms shape the biological and physicochemical qualities of the soil they choose to reside in, but our understanding of the specific chemicals that…”
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Behavioral Aversion to AITC Requires Both Painless and dTRPA1 in Drosophila by Mandel, Samantha J, Shoaf, Madison L, Braco, Jason T, Silver, Wayne L, Johnson, Erik C

“…There has been disagreement over the functional roles of the gene product in the detection and subsequent behavioral aversion to the active ingredient in…”
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Trigeminal collaterals in the nasal epithelium and olfactory bulb: A potential route for direct modulation of olfactory information by trigeminal stimuli by Schaefer, Michele L., Böttger, Bärbel, Silver, Wayne L., Finger, Thomas E.

“…The nasal epithelium is richly invested with peptidergic (substance P and calcitonin gene‐related peptide [CGRP]) trigeminal polymodal nociceptors, which…”
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Four Irritating Odorants Target the Trigeminal Chemoreceptor TRPA1 by Richards, Paige M., Johnson, Erik C., Silver, Wayne L.

“…The trigeminal nerve responds to a variety of nociceptive stimuli, including many chemicals that activate the olfactory system at lower concentrations…”
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Dissecting the role of TRPV1 in detecting multiple trigeminal irritants in three behavioral assays for sensory irritation [version 1; peer review: 2 approved] by Saunders, CJ, Li, Winston Y, Patel, Tulsi D, Muday, Jeffrey A, Silver, Wayne L

“…Polymodal neurons of the trigeminal nerve innervate the nasal cavity, nasopharynx, oral cavity and cornea. Trigeminal nociceptive fibers express a diverse…”
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The Anatomical and Electrophysiological Basis of Peripheral Nasal Trigeminal Chemoreception by Silver, Wayne L., Finger, Thomas E.

“…The trigeminal nerve (TN) provides sensory information from the eyes, nose, and mouth. A subset of trigeminal nerve fibers, particularly those containing the…”
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Mechanisms of carbon dioxide detection in the earthworm Dendrobaena veneta by Smith, Emily Jordan, Ryan, Jennifer L., Lopresti, Sofia A., Haghnazari, Dastan B. S., Anderson, Karleigh A. S., Lipson, Sarah J., Johnson, Erik C., Silver, Wayne L., Saunders, Cecil J.

“…Introduction Carbon dioxide (CO 2 ) is a critical biological signal that is noxious to many animals at high concentrations. The earthworm Dendrobaena veneta…”
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Naturally Produced Defensive Alkenal Compounds Activate TRPA1 by Blair, Nathaniel T, Philipson, Benjamin I, Richards, Paige M, Doerner, Julia F, Segura, Abraham, Silver, Wayne L, Clapham, David E

“…(E)-2-alkenals are aldehydes containing an unsaturated bond between the alpha and beta carbons. 2-alkenals are produced by many organisms for defense against…”
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Nasal Chemesthesis: Similarities Between Humans and Rats Observed in In Vivo Experiments by Alimohammadi, Hessamedin, Silver, Wayne L

“…INTRODUCTION: Recent advancements in the study of nasal chemesthesis have primarily been achieved through in vitro, cellular, and molecular techniques, with a…”
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TRPV1 Receptors and Nasal Trigeminal Chemesthesis by Silver, Wayne L., Clapp, Tod R., Stone, Leslie M., Kinnamon, Sue C.

“…The trigeminal nerve responds to a wide variety of irritants. Trigeminal nerve fibers express several receptors that respond to chemicals, including TRPV1…”
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Evidence for Nicotinic Acetylcholine Receptors on Nasal Trigeminal Nerve Endings of the Rat by Alimohammadi, Hessamedin, Silver, Wayne L.

“…The peripheral chemoreceptors of the trigeminal system in the nasal cavity are presumed to be free nerve endings arising from Aδ and C fibers. These fibers…”
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SYNAPSE, Symposium for Young Neuroscientists and Professors of the Southeast: A One-day, Regional Neuroscience Meeting Focusing on Undergraduate Research by Hurd, Mark W, Lom, Barbara, Silver, Wayne L

“…The Symposium for Young Neuroscientists and Professors of the Southeast (SYNAPSE; synapse.cofc.edu) was designed to encourage contacts among faculty and…”
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A novel T-maze assay to evaluate chemical irritants on Lumbricus terrestris by Silver, Wayne L., Kim, Albert H., Kim, Eui Y., Saunders, Cecil J.

“…•This soil T-maze is a useful tool to study the chemical avoidance behavior of individual earthworms.•Most animals detect irritating chemicals via the…”
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Ultrastructure of substance P- and CGRP-immunoreactive nerve fibers in the nasal epithelium of rodents by Finger, T E, St Jeor, V L, Kinnamon, J C, Silver, W L

“…The respiratory and olfactory mucosae of rats and mice were examined at ultrastructural levels for the presence of intraepithelial nerve endings…”
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Odorants presented to the rat nasal cavity increase cortical blood flow by MAJOR, D. A, SILVER, W. L

“…Complaints about unpleasant environmental odorants, both outdoor and indoor, are increasingly being reported. The main complaints of health symptoms from…”
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Introduction to Papers for the AChemS Symposium ‘Short-Term Effects of Environmental Chemicals’ by Walker, James C., Kendal-Reed, Martin, Silver, Wayne L.

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Inhibition by amiloride of chorda tympani responses evoked by monovalent salts by Brand, J G, Teeter, J H, Silver, W L

“…The diuretic, amiloride, is a potent yet reversible inhibitor of passive sodium transport in many epithelia. It has been shown to inhibit sodium transport in…”
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