Search Results - "Silveira, Paulo Flavio"

Differential efficiency of simvastatin and lipoic acid treatments on Bothrops jararaca envenomation-induced acute kidney injury in mice by Barone, Juliana Marton, Alponti, Rafaela Fadoni, Frezzatti, Rodrigo, Zambotti-Villela, Leonardo, Silveira, Paulo Flávio

“…Snake bite accidents by Bothrops genus is an important public health issue in Brazil and one of its most serious complications is the acute kidney injury…”
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Allopurinol reduces the lethality associated with acute renal failure induced by Crotalus durissus terrificus snake venom: comparison with probenecid by Frezzatti, Rodrigo, Silveira, Paulo Flavio

“…Acute renal failure is one of the most serious complications of envenoming resulting from Crotalus durissus terrificus bites. This study evaluated the…”
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Lipoic acid effects on renal function, aminopeptidase activities and oxidative stress in Crotalus durissus terrificus envenomation in mice by Alegre, Valter de Sousa, Barone, Juliana Marton, Yamasaki, Simone Cristina, Zambotti-Villela, Leonardo, Silveira, Paulo Flavio

“…Crotalus durissus terrificus envenomation has been associated with direct nephrotoxicity, rhabdomyolysis, hyperuricemia, urinary hypoosmolality, alterations in…”
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Basic aminopeptidase activity is an emerging biomarker in collagen-induced rheumatoid arthritis by Mendes, Mariana Trivilin, Murari-do-Nascimento, Stephanie, Torrigo, Isis Rossetti, Alponti, Rafaela Fadoni, Yamasaki, Simone Cristina, Silveira, Paulo Flavio

“…The objective of this study was to investigate the catalytic activity of basic aminopeptidase (APB) and its association with periarticular edema and…”
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APM/CD13 and FOS in the hypothalamus of monosodium glutamate obese and food deprived rats by Alponti, Rafaela Fadoni, Nogueira, Maria Inês, Mendes, Mariana Trivilin, de Abreu, Cintya, Silveira, Paulo Flavio

“…Protein (western blotting) and gene (PCR) expressions, catalytic activity of puromycin-insensitive membrane-bound neutral aminopeptidase (APM/CD13) and in situ…”
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Aminopeptidase activities, oxidative stress and renal function in Crotalus durissus terrificus envenomation in mice by Yamasaki, Simone Cristina, Villarroel, Joyce Siqueira, Barone, Juliana Marton, Zambotti-Villela, Leonardo, Silveira, Paulo Flávio

“…Acute renal failure is a serious condition of Crotalus bites, which could be treated with statins. The effects of Crotalus durissus terrificus venom ( vCdt)…”
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Peptidase activities in Crotalus durissus terrificus semen by Marinho, Camila Eduardo, Almeida-Santos, Selma Maria, Carneiro, Sylvia Mendes, Yamasaki, Simone Cristina, Silveira, Paulo Flavio

“…AbstractTo understand the role of peptidases in seminal physiology of Crotalus durissus terrificus, activity levels of representative enzymes in semen and…”
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Representative aminopeptidases and prolyl endopeptidase from murine macrophages: Comparative activity levels in resident and elicited cells by Olivo, Renata do Amaral, Teixeira, Catarina de Fátima Pereira, Silveira, Paulo Flávio

“…Macrophages are considered the main effector cells of immune system. Under stimulation these cells are known to be activated by a process involving…”
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Adipocyte aminopeptidases in obesity and fasting by Alponti, Rafaela Fadoni, Silveira, Paulo Flavio

“…This study checked the existence of a diverse array of aminopeptidase (AP) enzymes in high (HDM) and low (LDM) density microsomal and plasma membrane (MF)…”
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Identification of insulin-regulated aminopeptidase (IRAP) in the rat pineal gland and the modulation of melatonin synthesis by angiotensin IV by Abrahão, Mariana Vieira, dos Santos, Natália Fernanda Teixeira, Kuwabara, Wilson Mitsuo Tatagiba, do Amaral, Fernanda Gaspar, do Carmo Buonfiglio, Daniella, Peres, Rafael, Vendrame, Rafaela Fadoni Alponti, Flávio da Silveira, Paulo, Cipolla-Neto, José, Baltatu, Ovidiu Constantin, Afeche, Solange Castro

“…[Display omitted] •Ang IV potentiates NE-stimulated melatonin production in pinealocytes.•The (IRAP)/AT4 receptor is present in the rat pineal gland.•Ang IV…”
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Effects of obesity induced by high-calorie diet and its treatment with exenatide on muscarinic acetylcholine receptors in rat hippocampus by Silva, Marcelo Florencio Passos, Alves, Patricia Lucio, Alponti, Rafaela Fadoni, Silveira, Paulo Flavio, Abdalla, Fernando Maurício Francis

“…[Display omitted] Here, we described the effects of obesity induced by high-calorie diet and its treatment with exenatide, an anti-diabetogenic and potential…”
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Novel adipocyte aminopeptidases are selectively upregulated by insulin in healthy and obese rats by Alponti, Rafaela Fadoni, Alves, Patricia Lucio, Silveira, Paulo Flavio

“…The lack of a complete assembly of the sensitivity of subcellular aminopeptidase (AP) activities to insulin in different pathophysiological conditions has…”
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The Interrelationship between Leukotriene B4 and Leukotriene-A4-Hydrolase in Collagen/Adjuvant-Induced Arthritis in Rats by Mendes, Mariana Trivilin, Silveira, Paulo Flavio

“…This study aimed to check the involvement of lipid mediator leukotriene (LT) B4 and the activity of LTA4 hydrolase (LTA4H) in the development of arthritis…”
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Anti-obesogenic and hypolipidemic effects of a glucagon-like peptide-1 receptor agonist derived from the saliva of the Gila monster by Alves, Patricia Lucio, Abdalla, Fernando Mauricio Francis, Alponti, Rafaela Fadoni, Silveira, Paulo Flavio

“…Glucagon-like peptide-1 (GLP-1) receptor (R) agonists are a class of incretin mimetic drugs that have been used for the treatment of type 2 diabetes mellitus…”
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Effects of N-acetyl-l-cysteine on redox status and markers of renal function in mice inoculated with Bothrops jararaca and Crotalus durissus terrificus venoms by Barone, Juliana Marton, Frezzatti, Rodrigo, Silveira, Paulo Flavio

“…Renal dysfunction is an important aggravating factor in accidents caused by Crotalus durissus terrificus (Cdt) and Bothrops jararaca (Bj) bites…”
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Insulin-regulated aminopeptidase in adipocyte is Cys-specific and affected by obesity by Alponti, Rafaela Fadoni, Viana, Luciana Godoy, Yamanouye, Norma, Silveira, Paulo Flavio

“…Insulin-regulated aminopeptidase (IRAP, EC 3.4.11.3) in adipocytes is well known to traffic between high (HDM) and low (LDM) density microsomal fractions…”
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Neutral aminopeptidase and dipeptidyl peptidase IV in the development of collagen II-induced arthritis by Yamasaki, Simone Cristina, Murari-do-Nascimento, Stephanie, Silveira, Paulo Flavio

“…This study evaluated the hypothesis that neutral (APN) and dipeptidyl-IV (DPPIV) aminopeptidase activity levels would be critical for the susceptibility to…”
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Dipeptidyl peptidase IV in the hypothalamus and hippocampus of monosodium glutamate obese and food-deprived rats by Alponti, Rafaela Fadoni, Frezzatti, Rodrigo, Barone, Juliana Marton, Alegre, Valter de Sousa, Silveira, Paulo Flavio

“…Abstract Proline-specific dipeptidyl peptidases are emerging as a protease family with important roles in the regulation of signaling by peptide hormones…”
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Fluorometric assay using naphthylamide substrates for assessing novel venom peptidase activities by Gasparello-Clemente, Elaine, Silveira, Paulo Flávio

“…In the present study we examined the feasibility of using the fluorometry of naphthylamine derivatives for revealing peptidase activities in venoms of the…”
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Aminopeptidases in visceral organs during alterations in body fluid volume and osmolality by Gasparello-Clemente, Elaine, Casis, Luis, Varona, Adolfo, Gil, Javier, Irazusta, Jon, Silveira, Paulo Flávio

“…Enzymatic cleavage of some peptides in the local environment could be included among the mechanisms related to the regulation of hydrosaline balance. In order…”
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