Search Results - "Silva Prado, Douglas"

Neutrophil extracellular traps mediate bone erosion in rheumatoid arthritis by enhancing RANKL‐induced osteoclastogenesis by Schneider, Ayda Henriques, Taira, Thaise Mayumi, Públio, Gabriel Azevedo, Silva Prado, Douglas, Donate Yabuta, Paula Barbim, Santos, Jéssica Cristina, Machado, Caio Cavalcante, Souza, Flávio Falcão Lima, Rodrigues Venturini, Lucas Gabriel, Oliveira, Renê Donizeti Ribeiro, Cunha, Thiago Mattar, Alves‐Filho, José Carlos, Louzada‐Júnior, Paulo, Aparecida da Silva, Tarcília, Fukada, Sandra Yasuyo, Cunha, Fernando Queiróz

“…Background and Purpose Rheumatoid arthritis (RA) is a chronic autoimmune disease that can cause bone erosion due to increased osteoclastogenesis. Neutrophils…”
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PKM2 promotes Th17 cell differentiation and autoimmune inflammation by fine-tuning STAT3 activation by Damasceno, Luis Eduardo Alves, Prado, Douglas Silva, Veras, Flavio Protasio, Fonseca, Miriam M, Toller-Kawahisa, Juliana E, Rosa, Marcos Henrique, Públio, Gabriel Azevedo, Martins, Timna Varela, Ramalho, Fernando S, Waisman, Ari, Cunha, Fernando Queiroz, Cunha, Thiago Mattar, Alves-Filho, José Carlos

“…Th17 cell differentiation and pathogenicity depend on metabolic reprogramming inducing shifts toward glycolysis. Here, we show that the pyruvate kinase M2…”
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Inhalation of the prodrug PI3K inhibitor CL27c improves lung function in asthma and fibrosis by Campa, Carlo C., Silva, Rangel L., Margaria, Jean P., Pirali, Tracey, Mattos, Matheus S., Kraemer, Lucas R., Reis, Diego C., Grosa, Giorgio, Copperi, Francesca, Dalmarco, Eduardo M., Lima-Júnior, Roberto C. P., Aprile, Silvio, Sala, Valentina, Dal Bello, Federica, Prado, Douglas Silva, Alves-Filho, Jose Carlos, Medana, Claudio, Cassali, Geovanni D., Tron, Gian Cesare, Teixeira, Mauro M., Ciraolo, Elisa, Russo, Remo C., Hirsch, Emilio

“…PI3K activation plays a central role in the development of pulmonary inflammation and tissue remodeling. PI3K inhibitors may thus offer an improved therapeutic…”
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NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus by Ferreira, Nathanne Santos, Bruder-Nascimento, Thiago, Pereira, Camila André, Zanotto, Camila Zillioto, Prado, Douglas Silva, Silva, Josiane Fernandes, Rassi, Diane Meyre, Foss-Freitas, Maria Cristina, Alves-Filho, Jose Carlos, Carlos, Daniela, Tostes, Rita de Cássia

“…Aldosterone excess aggravates endothelial dysfunction in diabetes and hypertension by promoting the increased generation of reactive oxygen species,…”
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S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity by Silva de Melo, Bruno Marcel, Veras, Flávio Protásio, Zwicky, Pascale, Lima, Diógenes, Ingelfinger, Florian, Martins, Timna Varela, da Silva Prado, Douglas, Schärli, Stefanie, Publio, Gabriel, Hiroki, Carlos Hiroji, Melo, Paulo Henrique, Saraiva, André, Norbiato, Thainá, Lima, Leonardo, Ryffel, Bernhard, Vogl, Thomas, Roth, Johannes, Waisman, Ari, Nakaya, Helder I., da Silva Souza, Cacilda, Cunha, Fernando Q., Cunha, Thiago M., Becher, Burkhard, Alves-Filho, José C.

“…Psoriasis is a chronic inflammatory skin disorder driven by the IL-23/type 3 immune response. However, molecular mechanisms sustaining the chronicity of…”
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PI3Kγ controls IL-17A expression and attenuates alveolar bone loss in an experimental periodontitis model by Franchin, Marcelo, Taira, Thaise Mayumi, da Silva Prado, Douglas, Hernandez, Cesar Augusto Speck, de Andrade, Fabio Bonifácio, Abdalla, Henrique Ballassini, Napimoga, Marcelo Henrique, Cunha, Thiago Mattar, Fukada, Sandra Yasuyo, Rosalen, Pedro Luiz

“…Objective In this study, we investigated the modulatory effects of PI3Kγ on IL-17A expression and the progression of experimental periodontitis in vivo…”
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Galectin-3 aggravates experimental polymicrobial sepsis by impairing neutrophil recruitment to the infectious focus by Ferreira, Raphael G., Rodrigues, Lilian C., Nascimento, Daniele C., Kanashiro, Alexandre, Melo, Paulo H., Borges, Vanessa F., Gozzi, Aline, da Silva Prado, Douglas, Borges, Marcos C., Ramalho, Fernando S., Stowell, Sean R., Cummings, Richard D., Dias-Baruffi, Marcelo, Cunha, Fernando Q., Alves-Filho, Jose C.

“…Sepsis is an overwhelming systemic inflammation resulting from an uncontrolled infection that causes extensive tissue damage, organ dysfunction and eventually…”
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RESENHA DA TESE DE DOUTORADO “SABERES E FAZERES DE MULHERES CAMPONESAS E QUILOMBOLAS NAS AGRICULTURAS: PRODUZINDO FORMAS DE RESISTÊNCIAS E EXISTÊNCIAS”/Review of doctoral thesis “Knowledge and activities of peasant and quilombola women in agriculture: producing forms of resistance and existence” by Silva do Prado, Douglas, De Mello, Nilvania Aparecida

“…A tese de doutorado “Saberes e fazeres de mulheres camponesas e quilombolas nas agriculturas: produzindo formas de resistências e existências”, desenvolvida…”
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NLRP12 controls arthritis severity by acting as a checkpoint inhibitor of Th17 cell differentiation by Prado, Douglas Silva, Veras, Flavio P., Ferreira, Raphael Gomes, Damasceno, Luis Eduardo Alves, Melo, Paulo Henrique, Zamboni, Dario Simões, Cunha, Thiago Mattar, Cunha, Fernando Queiroz, Alves‐Filho, José Carlos

“…Nucleotide oligomerization domain (NOD)‐like receptor‐12 (NLRP12) has emerged as a negative regulator of inflammation. It is well described that the Th17 cell…”
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Cinnamoyloxy-mammeisin, a coumarin from propolis of stingless bees, attenuates Th17 cell differentiation and autoimmune inflammation via STAT3 inhibition by Franchin, Marcelo, Luiz Rosalen, Pedro, da Silva Prado, Douglas, César Paraluppi, Murilo, Leal Silva, Rangel, Damasceno, Luis Eduardo Alves, Morelo, David Fernando Colon, Napimoga, Marcelo Henrique, Cunha, Fernando Q., Alves-Filho, José C., Cunha, Thiago M.

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PPARγ receptors are involved in the effects of cannabidiol on orofacial dyskinesia and cognitive dysfunction induced by typical antipsychotic in mice by Sonego, Andreza Buzolin, Prado, Douglas da Silva, Guimarães, Francisco Silveira

“…Tardive dyskinesia (TD) is a movement disorder that appears after chronic use of drugs that block dopaminergic receptors such as antipsychotics. Besides the…”
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Abstract 770: Negative regulation of the CCL22/CCR4 axis by TNFR1 improves melanoma outcome by Leite, Caio Abner, Melo, Paulo Henrique, Mota, Jose Mauricio, Prado, Douglas Silva, Viacava, Paula Ramos, Cunha, Fernando Queiroz, Alves Filho, Jose Carlos

“…Purpose: Immunotherapy for melanoma skin cancer is mainly focused on preventing T cell deactivation through PD1 or CTLA4 inhibition. Another proposed mechanism…”
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História da Educação Profissional e Tecnológica: um panorama das dissertações e produtos educacionais defendidos no ProfEPT do IFPR entre 2020 e 2022 by Lemos Junior, Wilson, Prado, Douglas Silva do, Krugel, Vanessa Cauê, Costa, Juliane Aparecida Matos da

“…Utilizando como metodologia o estudo de caso, este artigo objetiva analisar as dissertações e produtos educacionais relacionados com a história da Educação…”
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Wound healing activity of (−)‐borneol complexed to chitosan bioactive film in rodents by de Souza Siqueira Barreto, Rosana, da Silva Prado, Douglas, Galvão, Juliana Gouveia, da Cunha Gonsalves, Joyce Kelly Marinheiro, de Souza Nunes, Rogéria, Albuquerque‐Júnior, Ricardo Luiz Cavalcanti, Soares, Rosilene Calazans, de Lucca, Waldecy, Quintans‐Junior, Lucindo

“…Abstract only…”
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Chemical composition, antinociceptive, anti-inflammatory and redox properties in vitro of the essential oil from Remirea maritima Aubl. (Cyperaceae) by Rabelo, Alessandra Silva, Serafini, Mairim Russo, Rabelo, Thallita Kelly, de Melo, Marcelia Garcez Dória, da Silva Prado, Douglas, Gelain, Daniel Pens, Moreira, José Claudio Fonseca, dos Santos Bezerra, Marília, da Silva, Thanany Brasil, Costa, Emmanoel Vilaça, de Lima Nogueira, Paulo Cesar, de Souza Moraes, Valéria Regina, do Nascimento Prata, Ana Paula, Quintans, Jr, Lucindo José, Araújo, Adriano Antunes Souza

“…The present study was carried out to evaluate antioxidant, antinociceptive and anti-inflammatory activities of essential oil from R. maritima (RMO) in…”
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