Evaluation of the resistance of Nellore, Curraleiro Pe-duro and Pantaneiro cattle breeds by experimental intoxication of Palicourea marcgravii

Evaluation of the resistance of Nellore, Curraleiro Pe-duro and Pantaneiro cattle breeds by experimental intoxication of Palicourea marcgravii

Palicourea marcgravii is the most important toxic plant in Brazil due to its acute toxicity (sudden death), palatability, cumulative effect and broad geographical distribution. The study aimed to evaluate the resistance between cattle of different breeds by experimental intoxication of Palicourea ma...

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Bibliographic Details
Published in:Toxicon (Oxford) Vol. 168; pp. 126 - 130
Main Authors: Serodio, Juliana J., Silva Castro, Luma T., Morais, Tábata L., Cunha, Roberta Dias da Silva, Ferreira de Sant’Ana, Fabiano J., Juliano, Raquel Soares, Junqueira Borges, José Renato, Soares Fioravanti, Maria C., Jorge da Cunha, Paulo H.
Format: Journal Article
Language:English
Published: England Elsevier Ltd 01-10-2019
Subjects:
Animals
Bovine
Cattle - genetics
Cattle Diseases - chemically induced
Genetic susceptibility
Kidney Diseases - chemically induced
Male
Plant Poisoning - veterinary
Rubiaceae - toxicity
Sodium monofluoroacetate
Species Specificity
Sudden death
Toxic plants
Sodium monofluoroacetate
Bovine
Genetic susceptibility
Toxic plants
Sudden death
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Summary:Palicourea marcgravii is the most important toxic plant in Brazil due to its acute toxicity (sudden death), palatability, cumulative effect and broad geographical distribution. The study aimed to evaluate the resistance between cattle of different breeds by experimental intoxication of Palicourea marcgravii. Eighteen males were randomly divided into three groups (Nellore, Curraleiro Pe-Duro and Pantaneiro), six animals in each group. All animals were experimentally intoxicated with P. marcgravii at 0.5 mg/kg of equivalent sodium monofluoracetate acid, receiving one single oral dose. All cattle presented symptoms and the toxic plant caused death in all cattle of the Nellore and Pantaneiro breeds and only three Curraleiro cattle. No changes were observed in the leukogram, fibrinogen, albumin, total protein and bilirubins. Hyperglycemia and increased of aspartate transaminase, creatinine kinase, urea and creatinine were detected in all breeds. Changes in the values of the gamma glutamyl transferase were individualized and did not follow a standard response. Fourteen cattle presented the histopathological findings of renal hydropic degeneration. The lower death rate of Curraleiro cattle indicates a higher resistance than cattle of the Nellore and Pantaneiro breeds. •All cattle of the Nellore, Pantaneiro and Curraleiro breeds presented symptoms.•The toxic plant caused death in all cattle of the Nellore and Pantaneiro breeds and only three Curraleiro cattle.•The lower death rate of Curraleiro cattle indicates a higher resistance than cattle of the Nellore and Pantaneiro breeds.•Selection of cattle resistant to Palicourea marcgravii poisoning could reduce cattle losses and improve rangeland utilization.
ISSN:0041-0101
1879-3150
DOI:10.1016/j.toxicon.2019.07.008