Search Results - "Silva Castanheira, Fernanda Vargas e"

ICAMs are dispensable for influenza clearance and anti-viral humoral and cellular immunity by Kozlovski, Stav, Regev, Ofer, Sapoznikov, Anita, Kizner, Marina, Achdout, Hagit, Petrovich-Kopitman, Ekaterina, Elkahal, Jacob, Addadi, Yoseph, Silva Castanheira, Fernanda Vargas E, Feigelson, Sara W, Kubes, Paul, Erez, Noam, Garbi, Natalio, Alon, Ronen

“…αLβ2 (LFA-1) mediated interactions with ICAM-1 and ICAM-2 predominate leukocyte-vascular interactions, but their functions in extravascular cell-cell…”
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Patrolling Alveolar Macrophages Conceal Bacteria from the Immune System to Maintain Homeostasis by Neupane, Arpan Sharma, Willson, Michelle, Chojnacki, Andrew Krzysztof, Vargas E Silva Castanheira, Fernanda, Morehouse, Christopher, Carestia, Agostina, Keller, Ashley Elaine, Peiseler, Moritz, DiGiandomenico, Antonio, Kelly, Margaret Mary, Amrein, Matthias, Jenne, Craig, Thanabalasuriar, Ajitha, Kubes, Paul

“…During respiration, humans breathe in more than 10,000 liters of non-sterile air daily, allowing some pathogens access to alveoli. Interestingly, alveoli…”
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Macrophage galactose lectin is critical for Kupffer cells to clear aged platelets by Deppermann, Carsten, Kratofil, Rachel M, Peiseler, Moritz, David, Bruna A, Zindel, Joel, Castanheira, Fernanda Vargas E Silva, van der Wal, Fardau, Carestia, Agostina, Jenne, Craig N, Marth, Jamey D, Kubes, Paul

“…Every day, megakaryocytes produce billions of platelets that circulate for several days and eventually are cleared by the liver. The exact removal mechanism,…”
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Neutrophil Extracellular Traps Induce Organ Damage during Experimental and Clinical Sepsis by Czaikoski, Paula Giselle, Mota, José Maurício Segundo Correia, Nascimento, Daniele Carvalho, Sônego, Fabiane, Castanheira, Fernanda Vargas e Silva, Melo, Paulo Henrique, Scortegagna, Gabriela Trentin, Silva, Rangel Leal, Barroso-Sousa, Romualdo, Souto, Fabrício Oliveira, Pazin-Filho, Antonio, Figueiredo, Florencio, Alves-Filho, José Carlos, Cunha, Fernando Queiróz

“…Organ dysfunction is a major concern in sepsis pathophysiology and contributes to its high mortality rate. Neutrophil extracellular traps (NETs) have been…”
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Paradoxical Roles of the Neutrophil in Sepsis: Protective and Deleterious by Sônego, Fabiane, Castanheira, Fernanda Vargas E Silva, Ferreira, Raphael Gomes, Kanashiro, Alexandre, Leite, Caio Abner Vitorino Gonçalves, Nascimento, Daniele Carvalho, Colón, David Fernando, Borges, Vanessa de Fátima, Alves-Filho, José Carlos, Cunha, Fernando Queiróz

“…Sepsis, an overwhelming inflammatory response syndrome secondary to infection, is one of the costliest and deadliest medical conditions worldwide. Neutrophils…”
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CCR2‐deficient mice are protected to sepsis by the disruption of the inflammatory monocytes emigration from the bone marrow by Cebinelli, Guilherme Cesar Martelossi, Lima, Kalil Alves, Silva Castanheira, Fernanda Vargas e, Hiroki, Carlos Hiroji, Monteiro, Valter Vinícius Silva, Lima, Mikhael Haruo Fernandes, Nascimento, Daniele Carvalho Bernardo, Alves Filho, José Carlos, Cunha, Thiago Mattar, Cunha, Fernando de Queiroz

“…Sepsis is defined as life‐threatening organ dysfunction caused by a dysregulated host response to infection. Inflammatory monocytes are recruited to both the…”
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A Functional Assessment of Fetal Liver and Monocyte-Derived Macrophages in the Lung Alveolar Environment by Zhang, Wen Xuan, Neupane, Arpan Sharma, David, Bruna Araujo, Ginhoux, Florent, Vargas E Silva Castanheira, Fernanda, Kubes, Paul

“…It is becoming clear that every organ is seeded by a population of fetal liver-derived macrophages that are replaced at different rates by monocyte-derived…”
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CCR5-Positive Inflammatory Monocytes are Crucial for Control of Sepsis by Castanheira, Fernanda Vargas e Silva, de Lima, Kalil Alves, Cebinelli, Guilherme Cesar Martelossi, Sônego, Fabiane, Kanashiro, Alexandre, Colon, David-Fernando, Borges, Vanessa, Czaikoski, Paula Giselle, Mota, José Mauricio, Cunha, Thiago Mattar, Alves-Filho, José Carlos, Liew, Foo Y, Cunha, Fernando Queiroz

“…ABSTRACTNeutrophils and inflammatory monocytes control sepsis by migration to the site of infection via their chemokine receptors. CCR5 is a chemokine receptor…”
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FK506 impairs neutrophil migration that results in increased polymicrobial sepsis susceptibility by Borges, Vanessa de Fátima, Galant, Leticia Selinger, Kanashiro, Alexandre, Castanheira, Fernanda Vargas e Silva, Monteiro, Valter Vinícius Silva, Duarte, Diego Ângelo, Rodrigues, Filipe Camargo, Silva, Camila Meirelles de Souza, Schneider, Ayda Henriques, Cebinelli, Guilherme Cesar Martelossi, de Lima, Mikhael Haruo Fernandes, Viola, João Paulo de Biaso, Cunha, Thiago Mattar, da Costa Neto, Claudio Miguel, Alves-Filho, José Carlos Farias, Pupo, André Sampaio, Cunha, Fernando de Queiroz

“…Objective This study aimed to investigate the effects of FK506 on experimental sepsis immunopathology. It investigated the effect of FK506 on leukocyte…”
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Intravital imaging of 3 different microvascular beds in SARS-CoV-2-infected mice by Vargas E Silva Castanheira, Fernanda, Nguyen, Rita, Willson, Michelle, Davoli-Ferreira, Marcela, Araujo David, Bruna, M Kelly, Margaret, Lee, Woo-Yong, Kratofil, Rachel M, Zhang, Wen Xuan, Bui-Marinos, Maxwell P, Corcoran, Jennifer A, Kubes, Paul

“…SARS-CoV-2 enters the respiratory tract where it infects the alveoli epithelial lining. However, patients have sequelae that extend well beyond the alveoli…”
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