Search Results - "Silva, Teresa P."
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Structural and Optical Characterization of Mechanochemically Synthesized CuSbS2 Compounds
Published in Materials (27-05-2022)“…One of the areas of research on materials for thin-film solar cells focuses on replacing In and Ga with more earth-abundant elements. In that respect,…”
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Scalable culture of human induced pluripotent cells on microcarriers under xeno‐free conditions using single‐use vertical‐wheel™ bioreactors
Published in Journal of chemical technology and biotechnology (1986) (01-12-2018)“…BACKGROUND Human induced pluripotent stem cells (hiPSC) are expected to become powerful tools for disease modelling, for the discovery and testing of new drugs…”
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Modeling Rett syndrome with human patient-specific forebrain organoids
Published in Frontiers in cell and developmental biology (10-12-2020)“…Copyright © 2020 Gomes, Fernandes, Vaz, Silva, Bekman, Xapelli, Duarte, Ghazvini, Gribnau, Muotri, Trujillo, Sebastião, Cabral and Diogo. This is an…”
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Maturation of Human Pluripotent Stem Cell-Derived Cerebellar Neurons in the Absence of Co-culture
Published in Frontiers in bioengineering and biotechnology (14-02-2020)“…The cerebellum plays a critical role in all vertebrates, and many neurological disorders are associated with cerebellum dysfunction. A major limitation in…”
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Design Principles for Pluripotent Stem Cell-Derived Organoid Engineering
Published in Stem cells international (01-01-2019)“…Human morphogenesis is a complex process involving distinct microenvironmental and physical signals that are manipulated in space and time to give rise to…”
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A Dynamic 3D Aggregate-Based System for the Successful Expansion and Neural Induction of Human Pluripotent Stem Cells
Published in Frontiers in cellular neuroscience (03-03-2022)“…The demand for large cell numbers for cellular therapies and drug screening applications requires the development of scalable platforms capable of generating…”
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Mesenchymal Stromal Cells’ Therapy for Polyglutamine Disorders: Where Do We Stand and Where Should We Go?
Published in Frontiers in cellular neuroscience (06-10-2020)“…Polyglutamine (polyQ) diseases are a group of inherited neurodegenerative disorders caused by expansion of the cytosine-adenine-guanine (CAG) repeat. This…”
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Cell Culture Process Scale-Up Challenges for Commercial-Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products
Published in Bioengineering (Basel) (25-02-2022)“…Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of…”
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Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation
Published in Stem cell research (01-05-2021)“…•Generation of human iPSCs carrying a BRCA2 c.156_157insAlu pathogenic mutation.•First human iPSCs carrying pathogenic mutations in the BRCA2 gene.•BRCA2…”
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Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c.3612delA
Published in Stem cell research (01-04-2021)“…How BRCA1 germline mutations predispose to cancer remains poorly understood. Induced pluripotent stem cells (iPSCs) represent an emerging model to investigate…”
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Unlocking the Secondary Critical Raw Material Potential of Historical Mine Sites, Lousal Mine, Southern Portugal
Published in Minerals (Basel) (01-02-2024)“…A steady supply of mineral raw materials is vital for the transition to a low-carbon, circular economy. The number of active mines in Europe has severely…”
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Challenges and Solutions for Commercial Scale Manufacturing of Allogeneic Pluripotent Stem Cell Products
Published in Bioengineering (Basel) (28-03-2020)“…Allogeneic cell therapy products, such as therapeutic cells derived from pluripotent stem cells (PSCs), have amazing potential to treat a wide variety of…”
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Orange Pickeringite from the Algares 30-Level Adit, Aljustrel Mine, Iberian Pyrite Belt, Portugal
Published in Minerals (Basel) (01-10-2021)“…The sheltered environment of the Algares +30 level adit (underground mine gallery) contributes to the preservation of secondary water-soluble minerals formed…”
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Contribution to the Understanding of the Colour Change in Bluish-Grey Limestones
Published in Heritage (01-09-2022)“…Bluish-grey limestones have been extensively used as ornamental stones for decoration purposes in buildings, as well as in works of art, and accordingly, have…”
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Mineral Inventory of the Algares 30-Level Adit, Aljustrel Mine, Iberian Pyrite Belt, Portugal
Published in Minerals (Basel) (01-10-2020)“…Mining activity in Algares (Aljustrel Mine, Portuguese sector of the Iberian Pyrite Belt, IPB) stems prior to Roman times. As the orebody is vertical and…”
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Models to study basic and applied aspects of lysosomal storage disorders
Published in Advanced drug delivery reviews (01-11-2022)“…© 2022 The Author(s). Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). The lack…”
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Transcriptome profiling of human pluripotent stem cell‐derived cerebellar organoids reveals faster commitment under dynamic conditions
Published in Biotechnology and bioengineering (01-07-2021)“…© 2021 Wiley Periodicals LLC Human-induced pluripotent stem cells (iPSCs) have great potential for disease modeling. However, generating iPSC-derived models to…”
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Glycosaminoglycan remodeling during chondrogenic differentiation of human bone marrow−/synovial-derived mesenchymal stem/stromal cells under normoxia and hypoxia
Published in Glycoconjugate journal (01-06-2020)“…Glycosaminoglycans (GAGs) are major components of cartilage extracellular matrix (ECM), which play an important role in tissue homeostasis not only by…”
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Physicochemical, morphological, thermal and pasting properties of a novel native starch obtained from annatto seeds
Published in Food hydrocolloids (01-04-2019)“…This work presents physicochemical, morphological, thermal, and pasting properties of a novel native starch obtained from defatted and depigmented annatto…”
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Ascertaining the degradation state of ceramic tiles: A preliminary non-destructive step in view of conservation treatments
Published in Applied clay science (01-09-2013)“…Conserving the cultural heritage is a general concern and the use of non-destructive techniques to characterize ancient materials is important. Serious…”
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