Search Results - "Silva, S. M"
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Lectin biosensors in cancer glycan biomarker detection
Published in Advances in clinical chemistry (2019)“…Cancer has high incidence and it will continue to increase over the next decades. Detection and quantification of cancer-associated biomarkers is frequently…”
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Chromones: A Promising Ring System for New Anti-inflammatory Drugs
Published in ChemMedChem (19-10-2016)“…The quest for safer anti‐inflammatory drugs is still the focus of several medicinal chemistry programs. Chromones (4H‐chromen‐4‐ones) are a group of naturally…”
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Special Issue "Recent Advances in the Synthesis, Functionalization and Applications of Pyrazole-Type Compounds II"
Published in Molecules (Basel, Switzerland) (01-08-2023)“…Pyrazole and its derivatives are considered privileged -heterocycles with immense therapeutic potential [...]…”
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4
Plant Flavonoids: Chemical Characteristics and Biological Activity
Published in Molecules (Basel, Switzerland) (04-09-2021)“…In recent years, more attention has been paid to natural sources of antioxidants. Flavonoids are natural substances synthesized in several parts of plants that…”
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Cancer serum biomarkers based on aberrant post-translational modifications of glycoproteins: Clinical value and discovery strategies
Published in Biochimica et biophysica acta (01-12-2015)“…Due to the increase in life expectancy in the last decades, as well as changes in lifestyle, cancer has become one of the most common diseases both in…”
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Macroalgae Specialized Metabolites: Evidence for Their Anti-Inflammatory Health Benefits
Published in Marine drugs (01-12-2022)“…Inflammation is an organism's response to chemical or physical injury. It is split into acute and chronic inflammation and is the last, most significant cause…”
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Effects of health at every size® interventions on health‐related outcomes of people with overweight and obesity: a systematic review
Published in Obesity reviews (01-12-2018)“…Summary Context The growing use of interventions based on the Health at Every Size® (HAES®) in obesity management. Objective This study aimed to summarize the…”
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Severe brain involvement in 5q spinal muscular atrophy type 0
Published in Annals of neurology (01-09-2019)“…Spinal muscular atrophy (SMA) type 0 is the most severe form of SMA, associated with the SMN1 gene and manifesting at birth. Most patients die in the first…”
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Zap1 is required for Candida glabrata response to fluconazole
Published in FEMS yeast research (27-01-2022)“…ABSTRACT The increasing prevalence of fluconazole-resistant clinical isolates of Candida spp. strongly hinders the widespread use of the drug. To tackle this…”
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Myasthenia Gravis and COVID-19: Clinical Characteristics and Outcomes
Published in Frontiers in neurology (11-09-2020)“…Myasthenia gravis (MG), an autoimmune neuromuscular disorder, may be a risk factor for severe COVID-19. We conducted an observational retrospective study with…”
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Genetic Diversity of Brazilian Bovine Pestiviruses Detected Between 1995 and 2014
Published in Transboundary and emerging diseases (01-04-2017)“…Summary Pestivirus infections in ruminants result in significant economic losses worldwide. The aetiological agents are three species from the genus…”
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De novo identification of satellite DNAs in the sequenced genomes of Drosophila virilis and D. americana using the RepeatExplorer and TAREAN pipelines
Published in PloS one (19-12-2019)“…Satellite DNAs are among the most abundant repetitive DNAs found in eukaryote genomes, where they participate in a variety of biological roles, from being…”
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Detection of the cancer-associated T antigen using an Arachis hypogaea agglutinin biosensor
Published in Biosensors & bioelectronics (15-09-2019)“…An impedimetric biosensor was developed for the selective detection of the cancer-associated T antigen, using the lectin from Arachis hypogaea (peanut…”
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Overview of phlorotannins’ constituents in Fucales
Published in Marine drugs (30-11-2022)“…Fucales are an order within the Phaeophyceae that include most of the common littoral seaweeds in temperate and subtropical coastal regions. Many species of…”
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Targeting neutrophils extracellular traps (NETs) reduces multiple organ injury in a COVID-19 mouse model
Published in Respiratory research (02-03-2023)“…COVID-19 is characterized by severe acute lung injury, which is associated with neutrophil infiltration and the release of neutrophil extracellular traps…”
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Monoterpene Hydroxy Lactones Isolated from Thalassiosira sp. Microalga and Their Antibacterial and Antioxidant Activities
Published in Molecules (Basel, Switzerland) (31-10-2024)“…Two monoterpenoid lactones, loliolide (1) and epi-loliolide (2), were isolated from the crude dichloromethane extract of a microalga, Thalassiosira sp.). The…”
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Flavonoids as Therapeutic Compounds Targeting Key Proteins Involved in Alzheimer’s Disease
Published in ACS chemical neuroscience (19-02-2014)“…Alzheimer’s disease is characterized by pathological aggregation of protein tau and amyloid-β peptides, both of which are considered to be toxic to neurons…”
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Age and sex influence the response in lipid metabolism of dehydrated Wistar rats
Published in Scientific reports (02-06-2022)“…Aging is associated a decrease in thirst sensation, which makes old people more susceptible to dehydration. Dehydration produces energy metabolism alterations…”
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Bioprospecting of Nitrogenous Heterocyclic Scaffolds with Potential Action for Neglected Parasitosis: A Review
Published in Current pharmaceutical design (01-01-2020)“…Neglected parasitic diseases are a group of infections currently considered as a worldwide concern. This fact can be attributed to the migration of these…”
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Whole‐Body MRI in Limb Girdle Muscular Dystrophy Type R1/2A: Correlation With Clinical Scores
Published in Muscle & nerve (01-10-2022)“…Introduction/Aim The most common limb girdle muscular dystrophy (LGMD) worldwide is LGMD type R1 (LGMDR1). The aim of this study was to correlate the MRI…”
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