Search Results - "Silva, Pedro Henrique Imenez"

Kidney metabolism and acid–base control: back to the basics by Imenez Silva, Pedro Henrique, Mohebbi, Nilufar

“…Kidneys are central in the regulation of multiple physiological functions, such as removal of metabolic wastes and toxins, maintenance of electrolyte and fluid…”
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Insights from Systems Biology in Physiological Studies: Learning from Context by Imenez Silva, Pedro Henrique, Melo, Diogo, de Mendonça, Pedro Omori Ribeiro 

“…Systems biology presents an integrated view of biological systems, focusing on the relations between elements, whether functional or evolutionary, and…”
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Alkali therapy protects renal function, suppresses inflammation, and improves cellular metabolism in kidney disease by Pastor Arroyo, Eva Maria, Yassini, Nima, Sakiri, Elif, Russo, Giancarlo, Bourgeois, Soline, Mohebbi, Nilufar, Amann, Kerstin, Joller, Nicole, Wagner, Carsten A, Imenez Silva, Pedro Henrique

“…Chronic kidney disease (CKD) affects approximately 10-13% of the population worldwide and halting its progression is a major clinical challenge. Metabolic…”
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Ovarian cancer G protein-coupled receptor 1 deficiency exacerbates crystal deposition and kidney injury in oxalate nephropathy in female mice by Yassini, Nima, Sprenger, Janine, Pastor Arroyo, Eva Maria, Krudewig, Christiane, Pellegrini, Giovanni, Joller, Nicole, Wagner, Carsten A, Imenez Silva, Pedro Henrique

“…Ovarian cancer G protein-coupled receptor 1 (OGR1) (Gpr68) and G protein-coupled receptor 4 (GPR4) (Gpr4) are proton-activated G protein-coupled receptors that…”
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Expression of NaPi-IIb in rodent and human kidney and upregulation in a model of chronic kidney disease by Motta, Sarah E., Imenez Silva, Pedro Henrique, Daryadel, Arezoo, Haykir, Betül, Pastor-Arroyo, Eva Maria, Bettoni, Carla, Hernando, Nati, Wagner, Carsten A.

“…Na + -coupled phosphate cotransporters from the SLC34 and SLC20 families of solute carriers mediate transepithelial transport of inorganic phosphate (Pi)…”
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The proton-activated ovarian cancer G protein-coupled receptor 1 (OGR1) is responsible for renal calcium loss during acidosis by Imenez Silva, Pedro Henrique, Katamesh-Benabbas, Chahira, Chan, Kessara, Pastor Arroyo, Eva Maria, Knöpfel, Thomas, Bettoni, Carla, Ludwig, Marie-Gabrielle, Gasser, Jürg A, Brandao-Burch, Andrea, Arnett, Timothy R, Bonny, Olivier, Seuwen, Klaus, Wagner, Carsten Alexander

“…Hypercalciuria is a common feature during metabolic acidosis and associates to nephrolithiasis and nephrocalcinosis. The mechanisms sensing acidosis and…”
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The mechanisms of alkali therapy in targeting renal diseases by Imenez Silva, Pedro Henrique, Wesson, Donald E, Wagner, Carsten A

“…Chronic kidney disease (CKD) is characterized by progressive reduction in kidney function and treatments aiming at stabilizing or slowing its progression may…”
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The Effect of Thiazide Diuretics on Urinary Prostaglandin E2 Excretion and Serum Sodium in the General Population by Geurts, Frank, Rudolphi, Crissy F, Pelouto, Anissa, van der Burgh, Anna C, Salih, Mahdi, Imenez Silva, Pedro Henrique, Fenton, Robert A, Chaker, Layal, Hoorn, Ewout J

“…Abstract Context Thiazide-induced hyponatremia is one of the most common forms of hyponatremia, but its pathogenesis is incompletely understood. Recent…”
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Serum sclerostin is associated with recurrent kidney stone formation independent of hypercalciuria by Rodríguez, Daniel, Gurevich, Ekaterina, Mohammadi Jouabadi, Soroush, Pastor Arroyo, Eva Maria, Ritter, Alexander, Estoppey Younes, Sandrine, Wagner, Carsten A, Imenez Silva, Pedro Henrique, Seeger, Harald, Mohebbi, Nilufar

“…Background Kidney stones are frequent in industrialized countries with a lifetime risk of 10 to 15%. A high percentage of individuals experience recurrence…”
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Distinct mechanisms underlie adaptation of proximal tubule Na+/H+ exchanger isoform 3 in response to chronic metabolic and respiratory acidosis by Silva, Pedro Henrique Imenez, Girardi, Adriana Castello Costa, Neri, Elida Adalgisa, Rebouças, Nancy Amaral

“…The Na +/ H + exchanger isoform 3 (NHE3) is essential for HCO 3 − reabsorption in renal proximal tubules. The expression and function of NHE3 must adapt to…”
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1430 Acid excretion is disturbed in calcium oxalate and calcium phosphate stone formers in the Swiss kidney stone cohort by Silva, Pedro Henrique Imenez, Aliaga, Isabel Rubio, Fuster, Daniel, Seeger, Harald, Ernandez, Thomas, Buchkremer, Florian, Dhayat, Nasser, Ritter, Alexander, Segerer, Stephan, Roth, Beat, Bonny, Olivier, Wagner, Carsten

“…Abstract Background and Aims Kidney stone is a highly prevalent disease worldwide that causes high morbidity and may increase the risk for chronic kidney…”
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The Effect of Thiazide Diuretics on Urinary Prostaglandin E2 Excretion and Serum Sodium in the General Population: SA-OR38 by Rudolphi, Crissy F., Geurts, Frank, Pelouto, Anissa, Burgh, Anna C. van der, Silva, Pedro Henrique Imenez, Salih, Mahdi, Chaker, Layal, Hoorn, Ewout J.

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FC 001ACIDOSIS AND ALKALI THERAPY ARE ASSOCIATED WITH TRANSCRIPTIONAL CHANGES AND ALTERED ABUNDANCE OF GENES INVOLVED IN CELL METABOLISM AND BICARBONATE TRANSPORT IN KIDNEY TRANSPLANT RECIPIENTS by Imenez Silva, Pedro Henrique, Wiegand, Anna, Daryadel, Arezoo, Gaspert, Ariana, Russo, Giancarlo, Wuthrich, Rudolf Peter, Wagner, Carsten, Mohebbi, Nilufar

“…Abstract Background and Aims Metabolic acidosis is a common event in kidney transplant recipients and has been associated to a higher risk of graft loss and…”
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Calcineurin inhibitor effects on kidney electrolyte handling and blood pressure: tacrolimus versus voclosporin by Wei, Kuang-Yu, van Heugten, Martijn H, van Megen, Wouter H, van Veghel, Richard, Rehaume, Linda M, Cross, Jennifer L, Viel, John J, van Willigenburg, Hester, Silva, Pedro Henrique Imenez, Danser, A H Jan, de Baaij, Jeroen H F, Hoorn, Ewout J

“…Calcineurin inhibitors affect kidney electrolyte handling and blood pressure through an effect on the distal tubule. The second generation calcineurin…”
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Intestinal epithelial ablation of Pit‐2/Slc20a2 in mice leads to sustained elevation of vitamin D3 upon dietary restriction of phosphate by Pastor‐Arroyo, Eva M., Knöpfel, Thomas, Imenez Silva, Pedro H., Schnitzbauer, Udo, Poncet, Nadège, Biber, Jürg, Wagner, Carsten A., Hernando, Nati

“…Aim Several Na+‐dependent phosphate cotransporters, namely NaPi‐IIb/SLC34A2, Pit‐1/SLC20A1 and Pit‐2/SLC20A2, are expressed at the apical membrane of…”
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862 – Intestinal Acidification Sensed by Ph-Sensing Receptor Gpr4 Contributes to Fibrogenesis by Weder, Bruce, van Haaften, Wouter Tobias, Baebler, Katharina, Rogler, Gerhard, Dijkstra, Gerard, Silva, Pedro Henrique Imenez, Wang, Yu, de Valliere, Cheryl, Wagner, Carsten, Frey-Wagner, Isabelle, Seuwen, Klaus, Ruiz-Castro, Pedro, Hausmann, Martin

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Cognitive impairment in CKD patients: a guidance document by the CONNECT network by Bolignano, Davide, Simeoni, Mariadelina, Hafez, Gaye, Pepin, Marion, Gallo, Antonio, Altieri, Manuela, Liabeuf, Sophie, Giannakou, Konstantinos, De, Ananya, Capasso, Giovambattista, Capasso, Giovambattista, Andrade, Alexandre, Arici, Mustafa, Bachmann, Maie, Bailey, Matthew, Barbieri, Michelangela, Bobot, Mickaël, Bruchfeld, Annette, Arune-Bumblyte, Inga, Rastenytė, Daiva, Calcutta, Antonello, Capolongo, Giovanna, Carriazo, Sol, Ceccarelli, Michele, Covic, Adrian Constantin, De, Ananya, Delgado, Pilar, Endlich, Nicole, Endres, Matthias, Esposito, Fabrizio, Farisco, Michele, Faucher, Quentin, Ferreira, Ana Carina, Figurek, Andreja, Fouque, Denis, Franssen, Casper, Fridolin, Ivo, Frische, Sebastian, Garneata, Liliana, Gesualdo, Loreto, Giannakou, Konstantinos, Godefroy, Olivier, Golenia, Aleksandra, Goumenos, Dimitrios, Jiménez, Eugenio Gutiérrez, Hafez, Gaye, Hoorn, Ewout, Silva, Pedro Henrique Imenez, Izhar, Raafiah, Kelly, Dearbhla, Kesler, Shelli, Klimkowicz-Mrowiec, Aleksandra, Knauss, Samuel, Kurganaite, Justina, Levassort, Hélène, Liabeuf, Sophie, Malyszko, Jolanta, Mani, Laila-Yasmin, Martino, Gianvito, Massy, Ziad, Mayer, Christopher, Mucci, Armida, Mutevelic-Turkovic, Alma, Nielsen, Rikke, Nitsch, Dorothea, Ortiz, Alberto, Panagiotopoulos, Vasileios, Karasavvidou, Despoina, Paolisso, Giuseppe, Pejušković, Bojana, Pepin, Marion, Perna, Alessandra, Perrottelli, Andrea, Pešić, Vesna, Pezzella, Pasquale, Rroji (Molla), Merita, Rychlík, Ivan, Sakkas, Giorgos, Simeoni, Mariadelina, Romeo, Maria José Soler, Spasovski, Goce, Starčević, Ana, Tedeschi, Gioacchino, Trevisani, Francesco, Unwin, Robert, Vazelov, Evgueniy, Wagner, Carsten Alexander, Wagner, Franca, Wanner, Christoph, Wiecek, Andrzej, Xu, Hong, Zacchia, Miriam, Zacharia, Lefteris, Zecchino, Irene, Zoccali, Carmine, Mattace-Raso, Francesco, Endlich, Karl-Hans, Perico, Norberto, Remuzzi, Giuseppe, Trepiccione, Francesco

“…Abstract Cognitive impairment (CI) is a prevalent and debilitating complication in patients with chronic kidney disease (CKD). This position paper, developed…”
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Drugs with a negative impact on cognitive functions (part 3): antibacterial agents in patients with chronic kidney disease by Liabeuf, Sophie, Hafez, Gaye, Pešić, Vesna, Spasovski, Goce, Bobot, Mickaël, Mačiulaitis, Romaldas, Bumblyte, Inga Arune, Ferreira, Ana Carina, Farinha, Ana, Malyszko, Jolanta, Pépin, Marion, Massy, Ziad A, Unwin, Robert, Capasso, Giovambattista, Mani, Laila-Yasmin

“…The relationship between chronic kidney disease (CKD) and cognitive function has received increased attention in recent years. Antibacterial agents (ABs)…”
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Cognitive decline related to chronic kidney disease as an exclusion factor from kidney transplantation: results from an international survey by Farisco, Michele, Blumblyte, Inga A, Franssen, Casper, Nitsch, Dorothea, Zecchino, Irene, Capasso, Giovambattista, Hafez, Gaye

“…Background and hypothesis There seems to be a lack of consensus on the necessity and the modality of psychological and specifically cognitive assessment of…”
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Differential responses of proximal tubule Na+/H+ exchanger NHE3 to low pH: comparison between metabolic and respiratory acidosis by Silva, Pedro Henrique Imenez, Girardi, Adriana Castello Costa, Rebouças, Nancy Amaral

“…Abstract only The Na +/ H + exchanger isoform 3 (NHE3) is essential for HCO 3 − reabsorption in renal proximal tubules. The goal of this work was to evaluate…”
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