Search Results - "Silva, Pedro A."
-
1
Interplay between Mutations and Efflux in Drug Resistant Clinical Isolates of Mycobacterium tuberculosis
Published in Frontiers in microbiology (27-04-2017)“…Numerous studies show efflux as a universal bacterial mechanism contributing to antibiotic resistance and also that the activity of the antibiotics subject to…”
Get full text
Journal Article -
2
Optimization approaches to Supervised Classification
Published in European journal of operational research (01-09-2017)“…•A review of optimization models for Supervised Classification.•Covers models based on geometrical arguments and Support Vector Machines.•Considers two-group…”
Get full text
Journal Article -
3
Streptomycin Resistance and Lineage-Specific Polymorphisms in Mycobacterium tuberculosis gidB Gene
Published in Journal of Clinical Microbiology (01-07-2011)“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text
Journal Article -
4
A novel algorithm for simultaneous SNP selection in high-dimensional genome-wide association studies
Published in BMC bioinformatics (31-10-2012)“…Identification of causal SNPs in most genome wide association studies relies on approaches that consider each SNP individually. However, there is a strong…”
Get full text
Journal Article -
5
Acetabular retroversion: Diagnosis and treatment
Published in EFORT Open Reviews (01-11-2018)“…Acetabular retroversion (AR) consists of a malorientation of the acetabulum in the sagittal plane. AR is associated with changes in load transmission across…”
Get full text
Journal Article -
6
Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains
Published in Antibiotics (Basel) (03-03-2018)“…With the growing body of knowledge on the contribution of efflux activity to drug resistance, increased attention has been given to the use of efflux…”
Get full text
Journal Article -
7
Modelling interval data with Normal and Skew-Normal distributions
Published in Journal of applied statistics (01-01-2012)“…A parametric modelling for interval data is proposed, assuming a multivariate Normal or Skew-Normal distribution for the midpoints and log-ranges of the…”
Get full text
Journal Article -
8
Antibiotics, cancer risk and oncologic treatment efficacy: a practical review of the literature
Published in Ecancermedicalscience (21-09-2020)“…Antibiotics have been extensively used to treat infectious diseases over the past century and have largely contributed to increased life expectancy over time…”
Get full text
Journal Article -
9
Proton Pump Inhibitors and Oncologic Treatment Efficacy: A Practical Review of the Literature for Oncologists
Published in Current oncology (Toronto) (03-02-2021)“…Proton pump inhibitors (PPIs) are the most commonly used anti-acid drugs worldwide, including among cancer patients. However, drug-drug interactions between…”
Get full text
Journal Article -
10
The multidrug transporters belonging to major facilitator superfamily in Mycobacterium tuberculosis
Published in Molecular medicine (Cambridge, Mass.) (01-11-2002)“…Both intrinsic and acquired multidrug resistance play an important role in the insurgence of tuberculosis. Detailed knowledge of the molecular basis of drug…”
Get full text
Journal Article -
11
Detection of Helicobacter pylori by Phenotypic and Genotypic Methods
Published in Digestive diseases and sciences (01-06-2010)“…Aims This research evaluated the utilization of a urease in-house test, culture and molecular method (ureA PCR) as a diagnostic tool for Helicobacter pylori…”
Get full text
Journal Article -
12
Learning curve and complications of minimally invasive transforaminal lumbar interbody fusion
Published in Neurosurgical focus (01-08-2013)“…Minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) has the potential advantage of minimizing soft-tissue damage and reducing recovery time…”
Get full text
Journal Article -
13
Parameter estimation for grouped data using EM and MCEM algorithms
Published in Communications in statistics. Simulation and computation (02-08-2024)“…Nowadays, the confidentiality of data and information is of great importance for many companies and organizations. For this reason, they may prefer not to…”
Get full text
Journal Article -
14
Discriminant Analysis of Interval Data: An Assessment of Parametric and Distance-Based Approaches
Published in Journal of classification (01-10-2015)“…Building on probabilistic models for interval-valued variables, parametric classification rules, based on Normal or Skew-Normal distributions, are derived for…”
Get full text
Journal Article -
15
Variability in electrophysiological properties and conducting obstacles controls re-entry risk in heterogeneous ischaemic tissue
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (12-06-2020)“…Ischaemia, in which inadequate blood supply compromises and eventually kills regions of cardiac tissue, can cause many types of arrhythmia, some…”
Get full text
Journal Article -
16
Estimation of Three-Phase Induction Motor Equivalent Circuit Parameters from Manufacturer Catalog Data
Published in Journal of Microwaves, Optoelectronics and Electromagnetic Applications (01-03-2017)“…Abstract The single phase equivalent circuit is largely used to model the three-phase induction motors in steady-state operation and under sinusoidal balanced…”
Get full text
Journal Article -
17
Enhancement of antibiotic activity by efflux inhibitors against multidrug resistant Mycobacterium tuberculosis clinical isolates from Brazil
Published in Frontiers in microbiology (2015)“…Drug resistant tuberculosis continues to increase and new approaches for its treatment are necessary. The identification of M. tuberculosis clinical isolates…”
Get full text
Journal Article -
18
Naphthoquinone Derivatives as Scaffold to Develop New Drugs for Tuberculosis Treatment
Published in Frontiers in microbiology (09-04-2018)“…Despite being a curable disease, tuberculosis (TB) remains a public health problem worldwide mainly due to lengthy treatment, as well as its toxic effects,…”
Get full text
Journal Article -
19
57Fe Mössbauer Analysis of Meteorites and Tektites
Published in Minerals (Basel) (12-06-2021)“…This review presents studies on iron meteorites (Campo del Cielo fall and an unregistered iron meteorite), an unregistered stony meteorite from Northwest…”
Get full text
Journal Article -
20
Synthesis and antimycobacterial activity of isoniazid derivatives from renewable fatty acids
Published in Bioorganic & medicinal chemistry (15-11-2013)“…This work describes the synthesis of a series of fatty acid hydrazide derivatives of isoniazid (INH). The compounds were tested against Mycobacterium…”
Get full text
Journal Article