Search Results - "Silva, Patricia B."
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Progesterone modulates TNF receptors expression by Jurkat cells cultured with plasma from pregnant women with preeclampsia
Published in International immunopharmacology (30-03-2024)“…•Preeclamptic women showed high plasma levels of sTNFR1 and TNF.•Plasma from preeclamptic women induced high TNFR1 expression by Jurkat cells.•Progesterone…”
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Pozzolanic Reaction of Recycled Cementitious and Red Ceramic-Waste Aggregates with Hydrated Lime for Pavement Base Layer
Published in Journal of materials in civil engineering (01-02-2023)“…AbstractCement addition and pozzolanic reaction in construction and demolition waste recycled aggregates can stabilize the base of pavements chemically. A way…”
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Characterization and trypanocidal activity of a β-lapachone-containing drug carrier
Published in PloS one (04-03-2021)“…The treatment of Chagas disease (CD), a neglected parasitic condition caused by Trypanosoma cruzi, is still based on only two drugs, nifurtimox (Nif) and…”
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In Vitro Activity of Copper(II) Complexes, Loaded or Unloaded into a Nanostructured Lipid System, against Mycobacterium tuberculosis
Published in International journal of molecular sciences (17-05-2016)“…Tuberculosis (TB) is an infectious disease caused mainly by the bacillus Mycobacterium tuberculosis (Mtb), presenting 9.5 million new cases and 1.5 million…”
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In Vitro , In Silico , and In Vivo Analyses of Novel Aromatic Amidines against Trypanosoma cruzi
Published in Antimicrobial agents and chemotherapy (01-02-2018)“…Five bis-arylimidamides were assayed as anti- agents by , , and approaches. None were considered to be pan-assay interference compounds. They had a favorable…”
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Nanostructured lipid carriers for incorporation of copper(II) complexes to be used against Mycobacterium tuberculosis
Published in Drug design, development and therapy (01-01-2017)“…Tuberculosis (TB) is a disease caused by . Cessation of treatment before the recommended conclusion may lead to the emergence of multidrug-resistant strains…”
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Novel Zinc(II) Complexes [Zn(atc-Et)₂] and [Zn(atc-Ph)₂]: In Vitro and in Vivo Antiproliferative Studies
Published in International journal of molecular sciences (21-05-2016)“…Cisplatin and its derivatives are the main metallodrugs used in cancer therapy. However, low selectivity, toxicity and drug resistance are associated with…”
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A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis
Published in Frontiers in microbiology (06-12-2018)“…Tuberculosis (TB) is an infectious, airborne disease caused by the bacterium that mainly affects the lungs. Fortunately, tuberculosis is a curable disease, and…”
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A Nanostructured Lipid System as a Strategy to Improve the in Vitro Antibacterial Activity of Copper(II) Complexes
Published in Molecules (Basel, Switzerland) (16-12-2015)“…The aim of this study was to construct a nanostructured lipid system as a strategy to improve the in vitro antibacterial activity of copper(II) complexes. New…”
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In vitro analyses of the effect of aromatic diamidines upon Trypanosoma cruzi
Published in Journal of antimicrobial chemotherapy (01-10-2009)“…Objectives Aromatic diamidines (ADs) have been recognized as promising antiparasitic agents. Therefore, in the present work, the in vitro trypanocidal effect…”
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Corrigendum: A Nanostructured Lipid System to Improve the Oral Bioavailability of Ruthenium(II) Complexes for the Treatment of Infections Caused by Mycobacterium tuberculosis
Published in Frontiers in microbiology (31-05-2019)“…[This corrects the article DOI: 10.3389/fmicb.2018.02930.]…”
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Thermoactivated cement from construction and demolition waste for pavement base stabilization: A case study in Brazil
Published in Waste management & research (21-02-2024)“…Construction and demolition waste (CDW) worldwide generation accounts 10 billion tonnes yearly. The major fraction is landfilled requiring innovative recycling…”
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Synthesis, characterization, and investigation of the thermal behavior of Cu(II) pyrazolyl complexes
Published in Journal of thermal analysis and calorimetry (01-11-2011)“…This work reports the synthesis, characterization, and thermal behavior of three complexes of copper (II): [CuCl 2 (HPz) 4 ] ( 1 ), [CuCl 2 (HdmPz) 4 ] ( 2 ),…”
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Functional loss of a noncanonical BCOR-PRC1.1 complex accelerates SHH-driven medulloblastoma formation
Published in Genes & development (01-09-2020)“…Medulloblastoma is a malignant childhood brain tumor arising from the developing cerebellum. In Sonic Hedgehog (SHH) subgroup medulloblastoma, aberrant…”
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miR‐367 promotes proliferation and stem‐like traits in medulloblastoma cells
Published in Cancer science (01-09-2015)“…In medulloblastoma, abnormal expression of pluripotency factors such as LIN28 and OCT4 has been correlated with poor patient survival. The miR‐302/367 cluster…”
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Antifungal activity and toxicity of an octyl gallate-loaded nanostructured lipid system on cells and nonmammalian animals
Published in Future microbiology (01-03-2022)“…Octyl gallate (OG) loaded into a nanostructured lipid system (NLS) was tested for antifungal activity and and toxicity. The features of NLS-OG were analyzed by…”
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YAP1 subgroup supratentorial ependymoma requires TEAD and nuclear factor I-mediated transcriptional programmes for tumorigenesis
Published in Nature communications (02-09-2019)“…YAP1 fusion-positive supratentorial ependymomas predominantly occur in infants, but the molecular mechanisms of oncogenesis are unknown. Here we show…”
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In Vitro Phenotypic Activity and In Silico Analysis of Natural Products from Brazilian Biodiversity on Trypanosoma cruzi
Published in Molecules (Basel, Switzerland) (18-09-2021)“…Chagas disease (CD) affects more than 6 million people worldwide. The available treatment is far from ideal, creating a demand for new alternative therapies…”
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A Novel Antifungal System With Potential for Prolonged Delivery of Histatin 5 to Limit Growth of Candida albicans
Published in Frontiers in microbiology (30-07-2019)“…Currently 75-88% of fungal infections are caused by species, and is the main microorganism that causes these infections, especially oral candidiasis. An option…”
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